Compile Data Set for Download or QSAR
Found 44 Enz. Inhib. hit(s) with Target = 'Lactoperoxidase'
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM217355(4-benzyl-2-hydroxybenzenecarbohydroxamic acid (HX2...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:The halogenation activities of LPO (EC 1.11.1.7) and TPO (EC 1.11.1.8) were determined using a modified method of that described previously [Ferrari ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K27DHPubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM50015089(2,N-Dihydroxy-benzamide | CHEMBL309339 | N,2-dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:The halogenation activities of LPO (EC 1.11.1.7) and TPO (EC 1.11.1.8) were determined using a modified method of that described previously [Ferrari ...More data for this Ligand-Target Pair
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM50238831(CHEMBL251689)copy SMILEScopy InChI
Affinity DataIC50: 800nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2XD7PubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM81461(CAS_86-54-4 | Hydralazine | Hydralazine (HZN) | NS...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2XD7PubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM217356(2-(benzylamino)-6-oxo-3H-pyrimidine-5-carbohydroxa...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:The halogenation activities of LPO (EC 1.11.1.7) and TPO (EC 1.11.1.8) were determined using a modified method of that described previously [Ferrari ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K27DHPubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM50238837(CHEMBL581893 | GNF-Pf-3346)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of cathepsin D.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2XD7PubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM50238832(CHEMBL4080413)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2XD7PubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM50238841(CHEMBL4098162)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:In vitro antagonist activity against rat prostatic androgen receptor (AR)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2XD7PubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM48320(4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-metho...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2XD7PubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM50238827(CHEMBL4064328)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2XD7PubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM50489048(CHEMBL2299190)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055GB
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM50489044(CHEMBL2299191)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055GB
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)copy SMILEScopy InChI
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2XD7PubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM50489043(CHEMBL2299192)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055GB
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM217354(2-(3,5-bistrifluoromethylbenzylamino)-6-oxo-1H-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 6.30E+3nMAssay Description:The halogenation activities of LPO (EC 1.11.1.7) and TPO (EC 1.11.1.8) were determined using a modified method of that described previously [Ferrari ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K27DHPubMed
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50507390(CHEMBL4482878 | US10981879, Example 3)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of human LPO assessed as reduction in H2O2 catalyzed 3,5-iodo tyrosine formation from 3-iodotyrosine and potassium iodide preincubated for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W0997ZPubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM50241361(CHEMBL1515 | METHIMAZOLE | US9138393, Methimazole ...)copy SMILEScopy InChI
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM50489045(CHEMBL2299193)copy SMILEScopy InChI
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055GB
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50275890(CHEMBL457523 | ethyl 2,3-dihydro-3-methyl-2-seleno...)copy SMILEScopy InChI
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31ZGKPubMed
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50275889(CHEMBL508102 | carbimazole)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31ZGKPubMed
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50275891(CHEMBL444464 | methyl 3-methyl-2-thioxo-2,3-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31ZGKPubMed
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50241361(CHEMBL1515 | METHIMAZOLE | US9138393, Methimazole ...)copy SMILEScopy InChI
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31ZGKPubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM50489042(CHEMBL2295876)copy SMILEScopy InChI
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055GB
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM50489049(CHEMBL2299195)copy SMILEScopy InChI
Affinity DataIC50: 1.43E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055GB
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM50489046(CHEMBL2299198)copy SMILEScopy InChI
Affinity DataIC50: 1.74E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055GB
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM50489041(CHEMBL2299196)copy SMILEScopy InChI
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055GB
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM7458(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)copy SMILEScopy InChI
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of bovine milk LPO assessed as reduction in NaOSCN production in presence of H2O2/NaSCN after 5 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2XD7PubMed
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50275895(CHEMBL469530 | methyl 3-ethyl-2-thioxo-2,3-dihydro...)copy SMILEScopy InChI
Affinity DataIC50: 1.96E+4nMAssay Description:Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31ZGKPubMed
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50275892(CHEMBL507966 | methyl 3-methyl-2-selenoxo-2,3-dihy...)copy SMILEScopy InChI
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31ZGKPubMed
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50275893(CHEMBL469529 | ethyl 3-ethyl-2-thioxo-2,3-dihydro-...)copy SMILEScopy InChI
Affinity DataIC50: 2.05E+4nMAssay Description:Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31ZGKPubMed
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50275894(CHEMBL446332 | ethyl 3-ethyl-2-selenoxo-2,3-dihydr...)copy SMILEScopy InChI
Affinity DataIC50: 2.13E+4nMAssay Description:Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31ZGKPubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM50489039(CHEMBL2299199)copy SMILEScopy InChI
Affinity DataIC50: 2.19E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055GB
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50275944(CHEMBL459114 | methyl 3-ethyl-2-selenoxo-2,3-dihyd...)copy SMILEScopy InChI
Affinity DataIC50: 2.53E+4nMAssay Description:Inhibition of lactoperoxidase (unknown origin)-catalyzed iodination of L-tyrosine assessed as 3,5-diiodo-L-tyrosine formation by HPLCMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z31ZGKPubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM50489047(CHEMBL2299194)copy SMILEScopy InChI
Affinity DataIC50: 2.64E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055GB
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM50489040(CHEMBL2299197)copy SMILEScopy InChI
Affinity DataIC50: 2.65E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055GB
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM50489038(CHEMBL2299200)copy SMILEScopy InChI
Affinity DataIC50: 3.46E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055GB
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50554034(CHEMBL4747269)copy SMILES
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of LPO (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4829PubMed
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50554035(CHEMBL4790231)copy SMILES
Affinity DataIC50: 6.20E+4nMAssay Description:Inhibition of LPO (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4829PubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM50489050(CHEMBL2299201)copy SMILEScopy InChI
Affinity DataIC50: 9.38E+4nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055GB
TargetLactoperoxidase(Homo sapiens (Human))
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50106515(7-Benzyloxy-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-y...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human LPO assessed as reduction in H2O2 catalyzed 3,5-iodo tyrosine formation from 3-iodotyrosine and potassium iodide preincubated for...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W0997ZPubMed
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM50489036(CHEMBL2299202)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+5nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055GB
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM50207306(CHEMBL2140153)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055GB
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM114830(3-(4-methoxyphenyl)-1H-isochromen-1-one | 3-(4-met...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055GB
TargetLactoperoxidase(Bos taurus (Bovine))
University of Otago Christchurch

LigandPNGBDBM50489037(CHEMBL2299203)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of Bos taurus (bovine) milk lactoperoxidase-catalyzed iodination of L-tyrosine substrate by reverse phase HPLC analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28055GB