Compile Data Set for Download or QSAR
Found 308 Enz. Inhib. hit(s) with Target = 'MAP kinase-activated protein kinase 5'
TargetMAP kinase-activated protein kinase 5(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe) Ltd.

Curated by ChEMBL
LigandPNGBDBM50341519((S)-3-(4-(2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of PRAKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KH0NPWPubMed
TargetMAP kinase-activated protein kinase 5(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe) Ltd.

Curated by ChEMBL
LigandPNGBDBM50224883(7-chloro-3-oxo-8-[(thiazol-5-ylmethyl)-amino]-11,1...)copy SMILEScopy InChI
Affinity DataKi: >1.53E+3nMAssay Description:Inhibition of PRAKMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X067WTPubMed
TargetMAP kinase-activated protein kinase 5(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe) Ltd.

Curated by ChEMBL
LigandPNGBDBM50463484(CHEMBL4248525)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of PRAK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC85HXPubMed
TargetMAP kinase-activated protein kinase 5(Homo sapiens (Human))
Vertex Pharmaceuticals (Europe) Ltd.

Curated by ChEMBL
LigandPNGBDBM50463479(CHEMBL4249925)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of PRAK (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZC85HXPubMed
LigandPNGBDBM605909(US11680056, Example 53A | US11680056, Example 53B)copy SMILES
Affinity DataIC50: 0.126nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605939(US11680056, Example 68B)copy SMILES
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605929(US11680056, Example 63B)copy SMILES
Affinity DataIC50: 0.316nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605911(US11680056, Example 54A | US11680056, Example 54B)copy SMILES
Affinity DataIC50: 0.631nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605920(US11680056, Example 59A | US11680056, Example 59B)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605918(US11680056, Example 58A)copy SMILES
Affinity DataIC50: 1.26nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605916(US11680056, Example 57A | US11680056, Example 57B)copy SMILES
Affinity DataIC50: 1.26nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605844(US11680056, Example 24A | US11680056, Example 24B)copy SMILES
Affinity DataIC50: 1.58nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605926(US11680056, Example 62A)copy SMILES
Affinity DataIC50: 1.58nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605936(US11680056, Example 67A)copy SMILES
Affinity DataIC50: 1.58nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605738(US11680056, Example 4 | US11680056, Example 4A | U...)copy SMILES
Affinity DataIC50: 1.58nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605930(US11680056, Example 64A | US11680056, Example 64B)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605914(US11680056, Example 56A | US11680056, Example 56B)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605897(US11680056, Example 47A | US11680056, Example 47B)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605838(US11680056, Example 21A | US11680056, Example 21B)copy SMILES
Affinity DataIC50: 3.16nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605842(US11680056, Example 23A | US11680056, Example 23B)copy SMILES
Affinity DataIC50: 3.16nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605924(US11680056, Example 61A | US11680056, Example 61B)copy SMILES
Affinity DataIC50: 3.16nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605932(US11680056, Example 65A | US11680056, Example 65B)copy SMILES
Affinity DataIC50: 3.98nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605824(US11680056, Example 9A)copy SMILES
Affinity DataIC50: 3.98nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605885(US11680056, Example 41A)copy SMILES
Affinity DataIC50: 5.01nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605877(US11680056, Example 37A | US11680056, Example 37B)copy SMILES
Affinity DataIC50: 5.01nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605873(US11680056, Example 36A)copy SMILES
Affinity DataIC50: 5.01nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605899(US11680056, Example 48A | US11680056, Example 48B)copy SMILES
Affinity DataIC50: 5.01nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605817(US11680056, Example 6 | US11680056, Example 6A | U...)copy SMILES
Affinity DataIC50: 5.01nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605935(US11680056, Example 66B)copy SMILES
Affinity DataIC50: 6.31nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605874(US11680056, Example 36B)copy SMILES
Affinity DataIC50: 6.31nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605901(US11680056, Example 49A | US11680056, Example 49B)copy SMILES
Affinity DataIC50: 6.31nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605854(US11680056, Example 29A | US11680056, Example 29B)copy SMILES
Affinity DataIC50: 7.94nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605916(US11680056, Example 57A | US11680056, Example 57B)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605881(US11680056, Example 39A | US11680056, Example 39B)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605732(US11680056, Example 3 | US11680056, Example 3A | U...)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605889(US11680056, Example 43A | US11680056, Example 43B)copy SMILES
Affinity DataIC50: 12.6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605848(US11680056, Example 26A | US11680056, Example 26B)copy SMILES
Affinity DataIC50: 12.6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605903(US11680056, Example 50A | US11680056, Example 50B)copy SMILES
Affinity DataIC50: 12.6nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605895(US11680056, Example 46A | US11680056, Example 46B)copy SMILES
Affinity DataIC50: 15.8nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605869(US11680056, Example 35A | US11680056, Example 35B ...)copy SMILES
Affinity DataIC50: 15.8nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605907(US11680056, Example 52A | US11680056, Example 52B)copy SMILES
Affinity DataIC50: 15.8nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605859(US11680056, Example 32A | US11680056, Example 32B ...)copy SMILES
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605865(US11680056, Example 34A)copy SMILES
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605923(US11680056, Example 60B)copy SMILES
Affinity DataIC50: 25.1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605891(US11680056, Example 44A | US11680056, Example 44B)copy SMILES
Affinity DataIC50: 25.1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605863(US11680056, Example 33A | US11680056, Example 33B)copy SMILES
Affinity DataIC50: 25.1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605869(US11680056, Example 35A | US11680056, Example 35B ...)copy SMILES
Affinity DataIC50: 50.1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605913(US11680056, Example 55)copy SMILES
Affinity DataIC50: 63.1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605905(US11680056, Example 51A)copy SMILES
Affinity DataIC50: 79.4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
LigandPNGBDBM605937(US11680056, Example 67B)copy SMILES
Affinity DataIC50: 79.4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5RXB
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