Compile Data Set for Download or QSAR
Found 18 Enz. Inhib. hit(s) with Target = 'Matrix metalloproteinase-26'
TargetMatrix metalloproteinase-26(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50365344(CHEMBL1956115)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP26More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VX0H0WPubMed
TargetMatrix metalloproteinase-26(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50305842(CHEMBL603656 | trans-4-((5-(2-(4-fluorobenzylcarba...)copy SMILEScopy InChI
Affinity DataKi: >2.50E+4nMAssay Description:Inhibition of MMP26More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9QHBPubMed
TargetMatrix metalloproteinase-26(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of matrix metalloproteinase-26 (MMP-26)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-26(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50062351((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibitory activity against MMP26More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ03C3PubMed
TargetMatrix metalloproteinase-26(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50137276(6-Hydroxy-7-methoxy-2-(4-methoxy-benzenesulfonyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 86nMAssay Description:Inhibition of matrix metalloproteinase-26 (MMP-26)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-26(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50137282(6-Hydroxy-2-(toluene-4-sulfonyl)-1,2,3,4-tetrahydr...)copy SMILEScopy InChI
Affinity DataIC50: 97nMAssay Description:Inhibition of matrix metalloproteinase-26 (MMP-26)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-26(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50137281(2-Benzenesulfonyl-6-hydroxy-7-methoxy-1,2,3,4-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 146nMAssay Description:Inhibition of matrix metalloproteinase-26 (MMP-26)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-26(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50137277(2-(4-Amino-benzenesulfonyl)-6-hydroxy-1,2,3,4-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 492nMAssay Description:Inhibition of matrix metalloproteinase-26 (MMP-26)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-26(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50137283(6-(benzyloxy)-N-hydroxy-2-(4-methoxyphenylsulfonyl...)copy SMILEScopy InChI
Affinity DataIC50: 744nMAssay Description:Inhibition of matrix metalloproteinase-26 (MMP-26)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-26(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50137279(6-Hydroxy-2-(4-nitro-benzenesulfonyl)-1,2,3,4-tetr...)copy SMILEScopy InChI
Affinity DataIC50: 791nMAssay Description:Inhibition of matrix metalloproteinase-26 (MMP-26)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-26(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50137284(2-Benzenesulfonyl-6-hydroxy-1,2,3,4-tetrahydro-iso...)copy SMILEScopy InChI
Affinity DataIC50: 858nMAssay Description:Inhibition of matrix metalloproteinase-26 (MMP-26)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-26(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50137287(2-Benzenesulfonyl-6-benzyloxy-1,2,3,4-tetrahydro-i...)copy SMILEScopy InChI
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of matrix metalloproteinase-26 (MMP-26)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-26(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50137285(6-(benzyloxy)-N-hydroxy-2-tosyl-1,2,3,4-tetrahydro...)copy SMILEScopy InChI
Affinity DataIC50: 2.05E+3nMAssay Description:Inhibition of matrix metalloproteinase-26 (MMP-26)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-26(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50137286(6-Hydroxy-2-(4-methoxy-benzenesulfonyl)-1,2,3,4-te...)copy SMILEScopy InChI
Affinity DataIC50: 7.51E+3nMAssay Description:Inhibition of matrix metalloproteinase-26 (MMP-26)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-26(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50137278(2-(2,5-Dichloro-benzenesulfonyl)-6-hydroxy-1,2,3,4...)copy SMILEScopy InChI
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of matrix metalloproteinase-26 (MMP-26)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22J6B79PubMed
TargetMatrix metalloproteinase-26(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50137278(2-(2,5-Dichloro-benzenesulfonyl)-6-hydroxy-1,2,3,4...)copy SMILEScopy InChI
Affinity DataIC50: 7.90E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GB281XPubMed
TargetMatrix metalloproteinase-26(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50063917((2S,3R)-N(4)-[(2S)-3,3-dimethyl-1-(methylamino)-1-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length human recombinant MMP26 using MCA-Arg-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-Glu-Arg-NH2 as substrate preincubated for 60 mins followe...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20G3N0FPubMedDrugBank
TargetMatrix metalloproteinase-26(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50180601(3-(4-(2-phenylethynyl)benzoyl)pentanoic acid | CHE...)copy SMILEScopy InChI
Affinity DataIC50: 1.81E+4nMAssay Description:Inhibitory activity against MMP26More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WQ03C3PubMed