Compile Data Set for Download or QSAR
Found 54 Enz. Inhib. hit(s) with Target = 'Methyl-CpG-binding domain protein 2'
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM158508(US9034574, XVII)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:DNA binding assays using recombinant MBDs. To produce recombinant His6-tagged MBD polypeptides from human MBD2 (MBD2-MBD), MBD2-MBD cDNA was amplifie...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SSNUS Patent
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM158511(US9034574, XXI)copy SMILEScopy InChI
Affinity DataIC50: 210nMAssay Description:DNA binding assays using recombinant MBDs. To produce recombinant His6-tagged MBD polypeptides from human MBD2 (MBD2-MBD), MBD2-MBD cDNA was amplifie...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SSNUS Patent
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM158510(US9034574, XX)copy SMILEScopy InChI
Affinity DataIC50: 470nMAssay Description:DNA binding assays using recombinant MBDs. To produce recombinant His6-tagged MBD polypeptides from human MBD2 (MBD2-MBD), MBD2-MBD cDNA was amplifie...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SSNUS Patent
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM158512(US9034574, XXII)copy SMILEScopy InChI
Affinity DataIC50: 670nMAssay Description:DNA binding assays using recombinant MBDs. To produce recombinant His6-tagged MBD polypeptides from human MBD2 (MBD2-MBD), MBD2-MBD cDNA was amplifie...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SSNUS Patent
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM114637(7-Methoxy-3-phenyl-2-p-tolyl-3H-9-oxa-1,3-diaza-an...)copy SMILEScopy InChI
Affinity DataIC50: 988nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM50264020(CHEMBL489770 | GNF-PF-4773 | N-(4-(pyridin-2-yl)th...)copy SMILEScopy InChI
Affinity DataIC50: 1.55E+3nMAssay Description:DNA binding assays using recombinant MBDs. To produce recombinant His6-tagged MBD polypeptides from human MBD2 (MBD2-MBD), MBD2-MBD cDNA was amplifie...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SSNUS Patent
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM158506(US9034574, II)copy SMILEScopy InChI
Affinity DataIC50: 1.55E+3nMAssay Description:DNA binding assays using recombinant MBDs. To produce recombinant His6-tagged MBD polypeptides from human MBD2 (MBD2-MBD), MBD2-MBD cDNA was amplifie...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SSNUS Patent
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM83848(MLS002702310 | N-[2-(dimethylamino)ethyl]-1-methox...)copy SMILEScopy InChI
Affinity DataIC50: 3.25E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM114652(CHEMBL1706858 | MLS003178551 | N-[3-(1,3-benzothia...)copy SMILEScopy InChI
Affinity DataIC50: 4.07E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM79511(MLS001116571 | N-(2-chlorobenzyl)-3-[(3-keto-4H-1,...)copy SMILEScopy InChI
Affinity DataIC50: 4.41E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM50284797(7-Methyl-6,7,7a,8-tetrahydro-5H-benzo[g][1,3]dioxo...)copy SMILEScopy InChI
Affinity DataIC50: 4.70E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM50699((2Z,3Z)-2-[4-(3,4-dimethoxyphenyl)-3H-1,3-thiazol-...)copy SMILEScopy InChI
Affinity DataIC50: 4.78E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM53262(2-[4-[(4-chlorophenyl)sulfonylamino]-1-hydroxynaph...)copy SMILEScopy InChI
Affinity DataIC50: 4.87E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM114653(CHEMBL1719929 | MLS003178552 | N-[3-(1,3-benzothia...)copy SMILEScopy InChI
Affinity DataIC50: 5.86E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM158507(US9034574, Add | US9034574, III)copy SMILEScopy InChI
Affinity DataIC50: 6.14E+3nMAssay Description:DNA binding assays using recombinant MBDs. To produce recombinant His6-tagged MBD polypeptides from human MBD2 (MBD2-MBD), MBD2-MBD cDNA was amplifie...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SSNUS Patent
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM114643(1-[2-(dimethylamino)ethylamino]-4-(hydroxymethyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 6.61E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM83853(7-chloranyl-2,3-dihydroimidazo[1,2-f]phenanthridin...)copy SMILEScopy InChI
Affinity DataIC50: 6.69E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM79562(1,2,4,6-tetraphenylpyridin-1-ium;perchlorate | MLS...)copy SMILEScopy InChI
Affinity DataIC50: 6.92E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM89192(3-(diethylamino)-N-(9,10-diketo-1-anthryl)propiona...)copy SMILEScopy InChI
Affinity DataIC50: 7.01E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM83394(3-benzyl-4-chloro-7-methyl-1H-1,8-naphthyridine-2-...)copy SMILEScopy InChI
Affinity DataIC50: 8.02E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM83852(2,3-dihydroimidazo[1,2-f]phenanthridine | Imidazo[...)copy SMILEScopy InChI
Affinity DataIC50: 8.08E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM89488(MLS002702308 | N-[2-(dimethylamino)ethyl]-8-methox...)copy SMILEScopy InChI
Affinity DataIC50: 8.21E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM114645(1-[2-(dimethylamino)ethylamino]-4-methyl-7-oxidany...)copy SMILEScopy InChI
Affinity DataIC50: 9.44E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM114651(CHEMBL1716096 | MLS002607798 | N-[3-(1,3-benzothia...)copy SMILEScopy InChI
Affinity DataIC50: 9.59E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM114640(2-[2,4-diphenyl-6-(p-tolyl)pyridin-1-ium-1-yl]benz...)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM48851(2-[6-(2-fluorobenzyl)-4-keto-5,7-dimethyl-pyrrolo[...)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM114650(MLS002607797 | N-[3-(1,3-benzothiazol-2-yl)-5,6,7,...)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM72391(2-[2-(diethylamino)ethyl]indeno[1,2,3-de]phthalazi...)copy SMILEScopy InChI
Affinity DataIC50: 1.34E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM114642(2,3-dimethoxy-6-[2-[(2S)-1-methyl-2-pyrrolidinyl]e...)copy SMILEScopy InChI
Affinity DataIC50: 1.35E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM114634(MLS000402538 | N-[2-amino-3-(1,3-benzothiazol-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.46E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM114646(MLS002702314 | N-[2-(dimethylamino)ethyl]-2-(4-pyr...)copy SMILEScopy InChI
Affinity DataIC50: 1.54E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM114638(4-(3-Dimethylamino-propylamino)-benzo[h]quinoline-...)copy SMILEScopy InChI
Affinity DataIC50: 1.71E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM114644(1-hydroxy-10,12-dimethoxy-8-methyl-4-(3,4,5-trihyd...)copy SMILEScopy InChI
Affinity DataIC50: 1.74E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM47509(5-nitro-2-(2-pyrrolidin-1-ylethyl)benzo[de]isoquin...)copy SMILEScopy InChI
Affinity DataIC50: 2.02E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM114649(CHEMBL1698064 | MLS002607791 | N-[3-(1,3-benzothia...)copy SMILEScopy InChI
Affinity DataIC50: 2.42E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM97005(MLS001199163 | N',N'-diethyl-N-(2-pyridin-4-yl-[1,...)copy SMILEScopy InChI
Affinity DataIC50: 2.43E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM114641(MLS001097547 | N-(6-amino-1-butyl-2,4-diketo-pyrim...)copy SMILEScopy InChI
Affinity DataIC50: 3.05E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM114639(6,8-Dimethyl-4-(3-morpholin-4-yl-propylamino)-quin...)copy SMILEScopy InChI
Affinity DataIC50: 3.18E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM114636(1-[(4-methylphenyl)methyl]-4-oxidanyl-3-(phenylmet...)copy SMILEScopy InChI
Affinity DataIC50: 3.51E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM114635(4-chloranyl-8-methyl-N-(3-pyrrolidin-1-ylpropyl)th...)copy SMILEScopy InChI
Affinity DataIC50: 3.73E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM158509(US9034574, XVIII)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+4nMAssay Description:DNA binding assays using recombinant MBDs. To produce recombinant His6-tagged MBD polypeptides from human MBD2 (MBD2-MBD), MBD2-MBD cDNA was amplifie...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5SSNUS Patent
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM114648(5-(1-butyl-1,2,3,4-tetrazol-5-yl)-1-(3-imidazol-1-...)copy SMILEScopy InChI
Affinity DataIC50: 4.37E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM114647(3-[6-[2-(dimethylamino)phenyl]-8-formamido-3-imida...)copy SMILEScopy InChI
Affinity DataIC50: 4.38E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM46563(4-chloranyl-N-[1-(phenylmethyl)pyrrolo[3,2-b]quino...)copy SMILEScopy InChI
Affinity DataIC50: 4.38E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM50533(3,4,5-trihydroxy-N'-((1E)-{4-methoxy-3-[(4-nit...)copy SMILEScopy InChI
Affinity DataIC50: 4.38E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM82809(4-[[(Z)-[1-(2-furanylmethyl)-2,4,6-trioxo-1,3-diaz...)copy SMILEScopy InChI
Affinity DataIC50: 4.38E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM48428(3-(2-chlorophenyl)-N-(2-furanylmethyl)-5-methyl-4-...)copy SMILEScopy InChI
Affinity DataIC50: 4.38E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM76030(4-[(2-cyano-1-oxoethyl)amino]benzoic acid [2-oxo-2...)copy SMILEScopy InChI
Affinity DataIC50: 4.38E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM40004((4-oxidanylidenepyrimido[2,1-b][1,3]benzothiazol-2...)copy SMILEScopy InChI
Affinity DataIC50: 4.38E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
TargetMethyl-CpG-binding domain protein 2(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM54065(MLS000877953 | N-(6-amino-1-benzyl-2,4-diketo-pyri...)copy SMILEScopy InChI
Affinity DataIC50: 4.38E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2778PCBioAssay
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