Compile Data Set for Download or QSAR
Found 54 Enz. Inhib. hit(s) with Target = 'Non-receptor tyrosine-protein kinase TYK2 [888-1187]'
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM294911(US10112907, Example 00020 | US10766894, Compound T...)copy SMILES
Affinity DataIC50: 2nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM294911(US10112907, Example 00020 | US10766894, Compound T...)copy SMILES
Affinity DataIC50: 2nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50355501(INCB-018424 | RUXOLITINIB | RUXOLITINIB PHOSPHATE ...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50311017(CHEMBL1078178 | Momelotinib | N-(cyanomethyl)-4-(2...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50311017(CHEMBL1078178 | Momelotinib | N-(cyanomethyl)-4-(2...)copy SMILEScopy InChI
Affinity DataIC50: 30nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50021656(BARICITINIB | INCB-028050 | LY-3009104 | US1011290...)copy SMILEScopy InChI
Affinity DataIC50: 30nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50021656(BARICITINIB | INCB-028050 | LY-3009104 | US1011290...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM294916(US10112907, Example 00027 | US10206907, Compound 1...)copy SMILEScopy InChI
Affinity DataIC50: 110nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM294916(US10112907, Example 00027 | US10206907, Compound 1...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM147644(US10766894, Compound TABLE 1.6 | US11203595, TABLE...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM294912(US10112907, Example 00021)copy SMILEScopy InChI
Affinity DataIC50: 110nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM294915(US10112907, Example 00026)copy SMILEScopy InChI
Affinity DataIC50: 120nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM462294(US10766894, Compound TABLE 1.11 | US11203595, TABL...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410174(US10370375, Example 22)copy SMILES
Affinity DataIC50: 130nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50402074(CHEMBL2206059 | US10112907, Example 00024 | US1076...)copy SMILEScopy InChI
Affinity DataIC50: 140nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50402074(CHEMBL2206059 | US10112907, Example 00024 | US1076...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 230nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50332294(CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50332294(CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...)copy SMILEScopy InChI
Affinity DataIC50: 310nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410170(US10370375, Example 18)copy SMILES
Affinity DataIC50: 390nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM103727(US10112907, Example 00033 | US10206907, Compound 2...)copy SMILEScopy InChI
Affinity DataIC50: 780nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM103727(US10112907, Example 00033 | US10206907, Compound 2...)copy SMILEScopy InChI
Affinity DataIC50: 780nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410178(US10370375, Example 26)copy SMILES
Affinity DataIC50: 840nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410177(US10370375, Example 25)copy SMILES
Affinity DataIC50: 1.10E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50021655(DECERNOTINIB | US10112907, Example 00017 | US10766...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM50021655(DECERNOTINIB | US10112907, Example 00017 | US10766...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM462293(US10766894, Compound TABLE 1.10 | US11203595, TABL...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20K2CRNUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM147692(US10112907, Example 00025 | US8962608, 28-1)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMpH: 7.5Assay Description:A kinase selectivity panel which measures substrate peptide phosphorylation was set-up for recombinant human Jak1 (aa 866-1154), Jak2 (aa808-1132), J...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FX7CHWUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410180(US10370375, Example 28)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410154(US10370375, Example 2)copy SMILES
Affinity DataIC50: 4.59E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410153(US10370375, Example 1)copy SMILES
Affinity DataIC50: 5.51E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410165(US10370375, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410179(US10370375, Example 27)copy SMILEScopy InChI
Affinity DataIC50: 7.80E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410176(US10370375, Example 24)copy SMILEScopy InChI
Affinity DataIC50: 8.50E+3nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410162(US10370375, Example 10)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410161(US10370375, Example 9)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410160(US10370375, Example 8)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410159(US10370375, Example 7)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410158(US10370375, Example 6)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410157(US10370375, Example 5)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410156(US10370375, Example 4)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410155(US10370375, Example 3)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410167(US10370375, Example 15)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410163(US10370375, Example 11)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410175(US10370375, Example 23)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410164(US10370375, Example 12)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410173(US10370375, Example 21)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
TargetNon-receptor tyrosine-protein kinase TYK2 [888-1187](Homo sapiens (Human))
NOVARTIS AG

US Patent
LigandPNGBDBM410172(US10370375, Example 20)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:All four kinases of the JAK/TYK-kinase family were used as purified recombinant GST-fusion proteins, containing the active kinase domains. GST-JAK1(8...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC857BUS Patent
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