Compile Data Set for Download or QSAR
Found 6 Enz. Inhib. hit(s) with Target = 'Phosphatidylcholine-sterol acyltransferase'
TargetPhosphatidylcholine-sterol acyltransferase(Homo sapiens (Human))
Dalhousie University

LigandPNGBDBM92615(Difluoroketone phospholipid analogue, 3)copy SMILEScopy InChI
Affinity DataIC50: 28nMpH: 7.5 T: 2°CAssay Description:The phospholipase A2 activity of LCAT was assayed using lecithin and apoA-I containing [9,10-3H] dipalmitoylphosphatidylcholine (DPPC) and measuremen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M0441T
TargetPhosphatidylcholine-sterol acyltransferase(Homo sapiens (Human))
Dalhousie University

LigandPNGBDBM92614(Difluoroketone phospholipid analogue, 2)copy SMILEScopy InChI
Affinity DataIC50: 60nMpH: 7.5 T: 2°CAssay Description:The phospholipase A2 activity of LCAT was assayed using lecithin and apoA-I containing [9,10-3H] dipalmitoylphosphatidylcholine (DPPC) and measuremen...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M0441T
TargetPhosphatidylcholine-sterol acyltransferase(Homo sapiens (Human))
Dalhousie University

LigandPNGBDBM92616(Difluoroketone phospholipid analogue, 4)copy SMILEScopy InChI
Affinity DataIC50: 60nMpH: 7.5 T: 2°CAssay Description:The phospholipase A2 activity of LCAT was assayed using lecithin and apoA-I containing [9,10-3H] dipalmitoylphosphatidylcholine (DPPC) and measuremen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M0441T
TargetPhosphatidylcholine-sterol acyltransferase(Homo sapiens (Human))
Dalhousie University

LigandPNGBDBM92613(Difluoroketone phospholipid analogue, 1)copy SMILEScopy InChI
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:The phospholipase A2 activity of LCAT was assayed using lecithin and apoA-I containing [9,10-3H] dipalmitoylphosphatidylcholine (DPPC) and measuremen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M0441T
TargetPhosphatidylcholine-sterol acyltransferase(Homo sapiens (Human))
Dalhousie University

LigandPNGBDBM303817((+)-cis-5-Hydroxy-4-(trifluoromethyl)-3-{1-[2-(tri...)copy SMILEScopy InChI
Affinity DataEC50:  18nMAssay Description:A fraction composed of HDL3 (1.125More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20C4XTVUS Patent
TargetPhosphatidylcholine-sterol acyltransferase(Homo sapiens (Human))
Dalhousie University

LigandPNGBDBM303816((+)-4,5-Dihydroxy-4-(trifluoromethyl)-3-{1-[5-(tri...)copy SMILEScopy InChI
Affinity DataEC50:  4nMAssay Description:A fraction composed of HDL3 (1.125More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20C4XTVUS Patent