Compile Data Set for Download or QSAR
Found 23 Enz. Inhib. hit(s) with Target = 'Protein farnesyltransferase alpha subunit/subunit beta'
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM50067584((S)-2-{[5-((R)-2-Amino-3-mercapto-propylamino)-bip...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM238375(3-(1-Dibenzofuranyl)-4-cyano-5-(isopropylthio)thio...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM238373(3-(3-Biphenyl)-4-cyano-5-(isopropylthio)thiophene-...)copy SMILEScopy InChI
Affinity DataIC50: 5.40E+3nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM238365(3-(3-(Methoxycarbonyl)phenyl)-4-cyano-5-(isopropyl...)copy SMILEScopy InChI
Affinity DataIC50: 6.90E+3nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM238361(3-(4-Methoxyphenyl)-4-cyano-5-(isopropylthio)thiop...)copy SMILEScopy InChI
Affinity DataIC50: 8.60E+3nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM238371(3-(2-Naphthyl)-4-cyano-5-(isopropylthio)thiophene-...)copy SMILEScopy InChI
Affinity DataIC50: 9.70E+3nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM238370(3-(1-Naphthyl)-4-cyano-5-(isopropylthio)thiophene-...)copy SMILEScopy InChI
Affinity DataIC50: 1.05E+4nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM238353(3-(4-Chlorophenyl)-4-cyano-5-(isopropylthio)thioph...)copy SMILEScopy InChI
Affinity DataIC50: 1.06E+4nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM238364(3-(4-(Methoxycarbonyl)phenyl)-4-cyano-5-(isopropyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM238354(3-(3-Chlorophenyl)-4-cyano-5-(isopropylthio)thioph...)copy SMILEScopy InChI
Affinity DataIC50: 1.45E+4nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM238367(3-(4-Tolyl)-4-cyano-5-(isopropylthio)thiophene-2-c...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM238362(3-(3-Methoxyphenyl)-4-cyano-5-(isopropylthio)thiop...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM238360(3-(3-(Trifluoromethyl)phenyl)-4-cyano-5-(isopropyl...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM238374(3-(3-Thienyl)-4-cyano-5-(isopropylthio)thiophene-2...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+4nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM238356(3-(4-Fluorophenyl)-4-cyano-5-(isopropylthio)thioph...)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+4nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM238372(3-(4-Biphenyl)-4-cyano-5-(isopropylthio)thiophene-...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+4nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM238357(3-(3-Fluorophenyl)-4-cyano-5-(isopropylthio)thioph...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+4nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM238368(3-(3-Tolyl)-4-cyano-5-(isopropylthio)thiophene-2-c...)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+4nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM238363(3-(2-Methoxyphenyl)-4-cyano-5-(isopropylthio)thiop...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+4nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM238355(3-(2-Chlorophenyl)-4-cyano-5-(isopropylthio)thioph...)copy SMILEScopy InChI
Affinity DataIC50: 3.70E+4nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM238366(3-Phenyl-4-cyano-5-(isopropylthio)thiophene-2-carb...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+4nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM238358(3-(2-Fluorophenyl)-4-cyano-5-(isopropylthio)thioph...)copy SMILEScopy InChI
Affinity DataIC50: 4.60E+4nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed
TargetProtein farnesyltransferase alpha subunit/subunit beta(Trypanosoma brucei brucei)
Centre de Recherche de Gif

LigandPNGBDBM238369(3-(2-Tolyl)-4-cyano-5-(isopropylthio)thiophene-2-c...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Assays were realized on 96-well plates, as described for human FTase with the dansylated peptide Dansyl-GCAIM and the solution contains 15 μL of...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2319TSJPubMed