Compile Data Set for Download or QSAR
Found 63 Enz. Inhib. hit(s) with Target = 'Putative glyoxylate/hydroxypyruvate reductase B'
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392802(7-(1-cyclohexylbenzimidazol-5-yl)-5-[[(2R)-1-methy...)copy SMILES
Affinity DataIC50: 0.400nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392796(5-[[(2R)-1-methylpyrrolidin-2-yl]methoxy]-7-(1-tet...)copy SMILES
Affinity DataIC50: 0.800nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392744(7-(1-Cyclohexyl-1H-benzimidazol-5-yl)-5-(hexahydro...)copy SMILES
Affinity DataIC50: 1.40nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392795(7-[1-[(1R,2R)-2-fluorocyclohexyl]benzimidazol-5-yl...)copy SMILES
Affinity DataIC50: 4nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392785(7-(3,4-Dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392774(US10301305, Example 136 | rac-1′-((trans)-3-...)copy SMILES
Affinity DataIC50: 5.70nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392793(7-(3,4-dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[[(...)copy SMILES
Affinity DataIC50: 6.20nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392801(7-(3,4-dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[(1...)copy SMILES
Affinity DataIC50: 6.5nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392786(6-(2-Dimethylamino-ethoxy)-1′-ethyl-1H,1R...)copy SMILEScopy InChI
Affinity DataIC50: 6.80nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392767(6-[(2-dimethylamino-ethyl)-methyl-amino]-1′-...)copy SMILES
Affinity DataIC50: 6.90nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392742(US10301305, Example 6 | {1-[7-(1-Cyclohexyl-1H-ben...)copy SMILEScopy InChI
Affinity DataIC50: 11nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392746(US10301305, Example 20 | {1-[4-(1-Cyclohexyl-1H-be...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392777(6-[(2-Dimethylamino-ethyl)-methyl-amino]-1′-...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392778(1′-(4,4-Difluoro-cyclohexyl)-6-[(2-dimethyla...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392779(1′-(2,2-Difluoro-ethyl)-6-[(2-dimethylamino-...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392781(1′-((1R,2R)-2-Fluoro-cyclohexyl)-6-[(2-hydro...)copy SMILES
Affinity DataIC50: 15nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392775(1′-Ethyl-6-[methyl-(2-methylamino-ethyl)-ami...)copy SMILES
Affinity DataIC50: 16nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392773(6-[(2-Dimethylamino-ethyl)-methyl-amino]-1′-...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392790(5-[2-(dimethylamino)ethyl-methyl-amino]-7-(1-pheny...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392787(6-[2-(dimethylamino)ethyl-methyl-amino]-4-(1-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392765(1′-Cyclohexyl-6-[(2-hydroxy-ethyl)-methyl-am...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392794(5-[4,4-bis(hydroxymethyl)-1-piperidyl]-7-(1-cycloh...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392769(1′-Cyclohexyl-6-[methyl-(2-pyrrolidin-1-yl-e...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392789(7-(1-butylbenzimidazol-5-yl)-5-[2-(dimethylamino)e...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392780(7-(3,4-Dihydro-5-oxa-1.2a-diaza-acenaphthylen-7-yl...)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392798(5-[2-(dimethylamino)ethyl-methyl-amino]-7-(1-ethyl...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392745((3R,4R)-1-[4-(1-Cyclohexyl-1H-benzimidazol-5-yl)-1...)copy SMILES
Affinity DataIC50: 33nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392760(6-Methoxy-1′-(1-methyl-cyclohexyl)-1H,1̸...)copy SMILEScopy InChI
Affinity DataIC50: 33nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392763(1′-Cyclohexyl-6-(4-methyl-piperazin-1-yl)-1H...)copy SMILEScopy InChI
Affinity DataIC50: 34nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392747(4-(1-Cyclohexyl-1H-benzimidazol-5-yl)-6-(hexahydro...)copy SMILES
Affinity DataIC50: 38nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392776(7-(3,4-Dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[(2...)copy SMILEScopy InChI
Affinity DataIC50: 39nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392797(7-(3,4-dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[3-...)copy SMILES
Affinity DataIC50: 47nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392755(1′-Cyclohexyl-6-fluoro-1H,1′H-[4,5R...)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392751((3R,4R)-1-(1′-Cyclohexyl-7-nitro-1H,1′...)copy SMILES
Affinity DataIC50: 49nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392784(7-(3,4-Dihydro-2H-pyrano[2,3-b]pyridin-6-yl)-5-[me...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392762(1′-Cyclohexyl-6-(2-dimethylamino-ethoxy)-1H,...)copy SMILEScopy InChI
Affinity DataIC50: 53nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392768(1′-Cyclohexyl-6-(2-dimethylaminomethyl-pyrro...)copy SMILES
Affinity DataIC50: 57nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392766(1′-Cyclohexyl-6-[(3-dimethylamino-propyl)-me...)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392800(5-[2-(dimethylamino)ethyl-methyl-amino]-7-(5-pyrro...)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392756(1′-Cyclohexyl-6-((S)-3-hydroxymethyl-pyrroli...)copy SMILES
Affinity DataIC50: 65nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392738((3R,4R)-1-[7-(1-Cyclohexyl-1H-benzimidazol-5-yl)-3...)copy SMILES
Affinity DataIC50: 66nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392757(1′-Cyclohexyl-6-(hexahydro-pyrrolo[3,4-c]pyr...)copy SMILES
Affinity DataIC50: 66nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392770(1′-Cyclohexyl-6-[(2-diethylamino-ethyl)-meth...)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392771(1′-Cyclohexyl-6-[(2-dimethylamino-ethyl)-(2-...)copy SMILEScopy InChI
Affinity DataIC50: 75nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392758(1′-Cyclohexyl-6-[3-(2-hydroxy-ethyl)-pyrroli...)copy SMILES
Affinity DataIC50: 77nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392749(1′-Cyclohexyl-6-(hexahydro-pyrrolo[3,4-c]pyr...)copy SMILES
Affinity DataIC50: 80nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392750(US10301305, Example 43 | [(S)-1-(1′-Cyclohex...)copy SMILES
Affinity DataIC50: 85nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392748(US10301305, Example 34 | [1-(1′-Cyclohexyl-1...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392788(4-(5-cyclopropylpyridin-3-yl)-6-((2-(dimethylamino...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
TargetPutative glyoxylate/hydroxypyruvate reductase B(Staphylococcus aureus (strain SA113))
GSK

LigandPNGBDBM392791(5-[2-(dimethylamino)ethyl-methyl-amino]-7-[6-(dime...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:The assay buffer “AB” contained 50 mM Hepes pH8.0, 10 mM MgCl2, 50 mM KCl, 0.012% Triton-X100, 10 mM DTT and 100 nM Myelin-basic protein. The followi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R213Q5US Patent
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