Compile Data Set for Download or QSAR
Found 81 Enz. Inhib. hit(s) with Target = 'Reduced folate transporter'
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50158569(2-S-[5-[2,4-diaminopteridin-6-yl)methyamino]-2,3-d...)copy SMILEScopy InChI
Affinity DataKi:  280nMAssay Description:Inhibition of RFC-mediated [3H]MTX influx into human CCRF-CEM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ873FPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50158570(2-R,S-[5-[(2,4-diaminopteridin-6-yl)methylamino]-2...)copy SMILEScopy InChI
Affinity DataKi:  530nMAssay Description:Inhibition of RFC-mediated [3H]MTX influx into human CCRF-CEM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ873FPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50158571(2-S-[5-[N-(2,4--diaminopteridin-6-yl)methyl)-N-met...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of RFC-mediated [3H]MTX influx into human CCRF-CEM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ873FPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)copy SMILEScopy InChI
Affinity DataKi:  3.50E+3nMAssay Description:Affinity towards RFC measured by the inhibition of [3H]-MTX uptakeMore data for this Ligand-Target Pair
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50457437(CHEBI:71223 | Folotyn | PDX | Pralatrexate)copy SMILEScopy InChI
Affinity DataIC50: 0.690nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as antiproliferative activity measured as reduction in cell viabili...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7SF1PubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50027655(CHEBI:5847 | Raltitrexed | Tomudex | US9422297, Ra...)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Inhibition of RFC (unknown origin) expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition incubated up to 96 hrs by Celltiter-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47QQSPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50027655(CHEBI:5847 | Raltitrexed | Tomudex | US9422297, Ra...)copy SMILEScopy InChI
Affinity DataIC50: 6.30nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as antiproliferative activity measured as reduction in cell viabili...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7SF1PubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Inhibition of RFC (unknown origin) expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition incubated up to 96 hrs by Celltiter-...More data for this Ligand-Target Pair
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM66082((2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methy...)copy SMILEScopy InChI
Affinity DataIC50: 12nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as antiproliferative activity measured as reduction in cell viabili...More data for this Ligand-Target Pair
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50503240(CHEMBL4445651)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as antiproliferative activity measured as reduction in cell growth ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048QFPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50027656(CHEBI:63616 | LY-2315 | LY-231514 | PEMETREXED | U...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Binding affinity to human RFC2 expressed in human HeLa R1-11 cells assessed as antiproliferative activity measured as reduction in cell growth after ...More data for this Ligand-Target Pair
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50027656(CHEBI:63616 | LY-2315 | LY-231514 | PEMETREXED | U...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as antiproliferative activity measured as reduction in cell growth ...More data for this Ligand-Target Pair
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50072403(CHEMBL3409335)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9CSQPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50126173(CHEMBL3628345)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K3PPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50072399(CHEMBL3407519)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9CSQPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50503236(CHEMBL4538151)copy SMILEScopy InChI
Affinity DataIC50: 62nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as antiproliferative activity measured as reduction in cell growth ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048QFPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50126172(CHEMBL3628344)copy SMILEScopy InChI
Affinity DataIC50: 63nMAssay Description:Binding affinity to human RFC2 expressed in human HeLa R1-11 cells assessed as antiproliferative activity measured as reduction in cell growth after ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048QFPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50503240(CHEMBL4445651)copy SMILEScopy InChI
Affinity DataIC50: 66nMAssay Description:Binding affinity to human RFC2 expressed in human HeLa R1-11 cells assessed as antiproliferative activity measured as reduction in cell growth after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048QFPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50354833(AGF94 | CHEMBL1834488)copy SMILEScopy InChI
Affinity DataIC50: 101nMAssay Description:Inhibition of RFC (unknown origin) expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition incubated up to 96 hrs by Celltiter-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47QQSPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50354833(AGF94 | CHEMBL1834488)copy SMILEScopy InChI
Affinity DataIC50: 101nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K3PPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50354833(AGF94 | CHEMBL1834488)copy SMILEScopy InChI
Affinity DataIC50: 106nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as antiproliferative activity measured as reduction in cell growth ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048QFPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50072401(CHEMBL3409334)copy SMILEScopy InChI
Affinity DataIC50: 116nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9CSQPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50027656(CHEBI:63616 | LY-2315 | LY-231514 | PEMETREXED | U...)copy SMILEScopy InChI
Affinity DataIC50: 138nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as antiproliferative activity measured as reduction in cell viabili...More data for this Ligand-Target Pair
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50027656(CHEBI:63616 | LY-2315 | LY-231514 | PEMETREXED | U...)copy SMILEScopy InChI
Affinity DataIC50: 138nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assayMore data for this Ligand-Target Pair
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50027656(CHEBI:63616 | LY-2315 | LY-231514 | PEMETREXED | U...)copy SMILEScopy InChI
Affinity DataIC50: 138nMAssay Description:Inhibition of RFC (unknown origin) expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition incubated up to 96 hrs by Celltiter-...More data for this Ligand-Target Pair
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50126174(CHEMBL3628346)copy SMILEScopy InChI
Affinity DataIC50: 189nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K3PPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50126172(CHEMBL3628344)copy SMILEScopy InChI
Affinity DataIC50: 197nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as antiproliferative activity measured as reduction in cell growth ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048QFPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50126172(CHEMBL3628344)copy SMILEScopy InChI
Affinity DataIC50: 197nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K3PPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50503238(CHEMBL4465095)copy SMILEScopy InChI
Affinity DataIC50: 213nMAssay Description:Binding affinity to human RFC2 expressed in human HeLa R1-11 cells assessed as antiproliferative activity measured as reduction in cell growth after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048QFPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50072404(CHEMBL3409336)copy SMILEScopy InChI
Affinity DataIC50: 243nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9CSQPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50171513((S)-2-(4-(3-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[...)copy SMILEScopy InChI
Affinity DataIC50: 304nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as antiproliferative activity measured as reduction in cell growth ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048QFPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50354833(AGF94 | CHEMBL1834488)copy SMILEScopy InChI
Affinity DataIC50: 444nMAssay Description:Binding affinity to human RFC2 expressed in human HeLa R1-11 cells assessed as antiproliferative activity measured as reduction in cell growth after ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048QFPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50503239(CHEMBL4557278)copy SMILEScopy InChI
Affinity DataIC50: 468nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as antiproliferative activity measured as reduction in cell growth ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048QFPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50503236(CHEMBL4538151)copy SMILEScopy InChI
Affinity DataIC50: 507nMAssay Description:Binding affinity to human RFC2 expressed in human HeLa R1-11 cells assessed as antiproliferative activity measured as reduction in cell growth after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048QFPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50534427(CHEMBL4437824)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of human RFC expressed in Chinese hamster PC43-10 cells assessed as antiproliferative activity measured as reduction in cell viability aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4V5FPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50457435(CHEMBL4214638)copy SMILEScopy InChI
Affinity DataIC50: 634nMAssay Description:Binding affinity to human RFC2 expressed in human HeLa R1-11 cells assessed as antiproliferative activity measured as reduction in cell growth after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M048QFPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50534431(CHEMBL4447805)copy SMILEScopy InChI
Affinity DataIC50: 641nMAssay Description:Inhibition of human RFC expressed in Chinese hamster PC43-10 cells assessed as antiproliferative activity measured as reduction in cell viability aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4V5FPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50534430(CHEMBL4471269)copy SMILEScopy InChI
Affinity DataIC50: 642nMAssay Description:Inhibition of human RFC expressed in Chinese hamster PC43-10 cells assessed as antiproliferative activity measured as reduction in cell viability aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4V5FPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50534426(CHEMBL4553188)copy SMILEScopy InChI
Affinity DataIC50: 783nMAssay Description:Inhibition of human RFC expressed in Chinese hamster PC43-10 cells assessed as antiproliferative activity measured as reduction in cell viability aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4V5FPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50534429(CHEMBL4444011)copy SMILEScopy InChI
Affinity DataIC50: 808nMAssay Description:Inhibition of human RFC expressed in Chinese hamster PC43-10 cells assessed as antiproliferative activity measured as reduction in cell viability aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4V5FPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50027657(CHEMBL3335607)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of RFC (unknown origin) expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition incubated up to 96 hrs by Celltiter-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47QQSPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50027658(CHEMBL3335606)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of RFC (unknown origin) expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition incubated up to 96 hrs by Celltiter-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47QQSPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50027654(CHEMBL3335605)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of RFC (unknown origin) expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition incubated up to 96 hrs by Celltiter-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47QQSPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50027659(CHEMBL3335604)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of RFC (unknown origin) expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition incubated up to 96 hrs by Celltiter-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47QQSPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50027660(CHEMBL3335603)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of RFC (unknown origin) expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition incubated up to 96 hrs by Celltiter-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F47QQSPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50306576((S)-2-({5-[4-(2-Amino-4-oxo-4,7-dihydro-3H-pyrrolo...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9CSQPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50072398(CHEMBL2426245)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9CSQPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50072406(CHEMBL3409337)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26W9CSQPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50126175(CHEMBL3628347)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as cell growth inhibition after 96 hrs by CellTiter-Blue assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QJ7K3PPubMed
TargetReduced folate transporter(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50457431(CHEMBL4218109)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to human RFC expressed in Chinese hamster PC43-10 cells assessed as antiproliferative activity measured as reduction in cell viabili...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7SF1PubMed
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