Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Replicase polyprotein 1ab [3264-3569]'
TargetReplicase polyprotein 1ab [3264-3569](Severe acute respiratory syndrome coronavirus 2)
University of Lubeck

LigandPNGBDBM420283(alpha-ketoamide inhibitor 11r | med.21724, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:A fluorescent substrate harboring the cleavage site (indicated by the arrow, ↓) of SARS-CoV-2 Mpro(Dabcyl-KTSAVLQ↓SGFRKM-E(Edans)-NH2; GL...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7689PubMed
TargetReplicase polyprotein 1ab [3264-3569](Severe acute respiratory syndrome coronavirus 2)
University of Lubeck

LigandPNGBDBM420295(alpha-ketoamide inhibitor 13b | med.21724, Compoun...)copy SMILEScopy InChI
Affinity DataIC50: 670nMAssay Description:A fluorescent substrate harboring the cleavage site (indicated by the arrow, ↓) of SARS-CoV-2 Mpro(Dabcyl-KTSAVLQ↓SGFRKM-E(Edans)-NH2; GL...More data for this Ligand-Target Pair
Ligand InfoPurchaseMCE
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7689PubMed
TargetReplicase polyprotein 1ab [3264-3569](Severe acute respiratory syndrome coronavirus 2)
University of Lubeck

LigandPNGBDBM420293(alpha-ketoamide inhibitor 13a)copy SMILEScopy InChI
Affinity DataIC50: 2.39E+3nMAssay Description:A fluorescent substrate harboring the cleavage site (indicated by the arrow, ↓) of SARS-CoV-2 Mpro(Dabcyl-KTSAVLQ↓SGFRKM-E(Edans)-NH2; GL...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2CN7689PubMed