Compile Data Set for Download or QSAR
Found 249 Enz. Inhib. hit(s) with Target = 'Runt-related transcription factor 1'
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM31183(thiazol-2-amine, 14)copy SMILEScopy InChI
Affinity DataIC50: 700nMAssay Description:His6-CBFbeta (1-141) was expressed and purified with the exception of the protease cleavage step. Cerulean-Runt domain fusion protein (Runx1 41-190) ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862DTNPubMed
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29675(2-methyl-N-(4-thiazolo[5,4-b]pyridin-2-ylphenyl)-1...)copy SMILEScopy InChI
Affinity DataIC50: 713nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25D8Q6QPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM31183(thiazol-2-amine, 14)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMpH: 7.5 T: 2°CAssay Description:For the FRET measurements, the Cerulean-Runt (Runx1 41-190) and Venus-CBFbeta (1-141) fusion proteins were dialyzed into FRET assay buffer. Protein c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862DTNPubMed
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM434071(US10562890, Compound Al-12-16)copy SMILEScopy InChI
Affinity DataIC50: 1.69E+3nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM434079(US10562890, Compound Al-14-72)copy SMILEScopy InChI
Affinity DataIC50: 1.72E+3nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29652(5-chloranyl-N-[4-([1,3]thiazolo[5,4-b]pyridin-2-yl...)copy SMILEScopy InChI
Affinity DataIC50: 1.87E+3nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25D8Q6QPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM434076(US10562890, Compound Al-14-100)copy SMILEScopy InChI
Affinity DataIC50: 2.16E+3nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM434075(US10562890, Compound Al-14-95)copy SMILEScopy InChI
Affinity DataIC50: 2.65E+3nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM434070(US10562890, Compound Al-10-104)copy SMILEScopy InChI
Affinity DataIC50: 2.65E+3nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM434074(US10562890, Compound Al-14-91)copy SMILEScopy InChI
Affinity DataIC50: 2.97E+3nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM31175(thiazol-2-amine, 5)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:His6-CBFbeta (1-141) was expressed and purified with the exception of the protease cleavage step. Cerulean-Runt domain fusion protein (Runx1 41-190) ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862DTNPubMed
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM434069(US10562890, Compound Al-10-47)copy SMILEScopy InChI
Affinity DataIC50: 3.19E+3nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM31185(thiazol-2-amine, 17)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMpH: 7.5 T: 2°CAssay Description:For the FRET measurements, the Cerulean-Runt (Runx1 41-190) and Venus-CBFbeta (1-141) fusion proteins were dialyzed into FRET assay buffer. Protein c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862DTNPubMed
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM31186(thiazol-2-amine, 18)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+3nMAssay Description:His6-CBFbeta (1-141) was expressed and purified with the exception of the protease cleavage step. Cerulean-Runt domain fusion protein (Runx1 41-190) ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862DTNPubMed
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM31182(thiazol-2-amine, 13)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:His6-CBFbeta (1-141) was expressed and purified with the exception of the protease cleavage step. Cerulean-Runt domain fusion protein (Runx1 41-190) ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862DTNPubMed
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM31185(thiazol-2-amine, 17)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:His6-CBFbeta (1-141) was expressed and purified with the exception of the protease cleavage step. Cerulean-Runt domain fusion protein (Runx1 41-190) ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862DTNPubMed
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29666((9-Oxo-9H-acridin-10-yl)-acetic acid [1-(4-chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 3.58E+3nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25D8Q6QPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM30648(MLS-0062362.0001 | N-(4-thiazolo[5,4-b]pyridin-2-y...)copy SMILEScopy InChI
Affinity DataIC50: 3.64E+3nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25D8Q6QPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM434072(US10562890, Compound Al-14-55)copy SMILEScopy InChI
Affinity DataIC50: 4.83E+3nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM434078(US10562890, Compound Al-14-18)copy SMILEScopy InChI
Affinity DataIC50: 4.97E+3nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM31182(thiazol-2-amine, 13)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMpH: 7.5 T: 2°CAssay Description:For the FRET measurements, the Cerulean-Runt (Runx1 41-190) and Venus-CBFbeta (1-141) fusion proteins were dialyzed into FRET assay buffer. Protein c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862DTNPubMed
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM31178(thiazol-2-amine, 8)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+3nMAssay Description:His6-CBFbeta (1-141) was expressed and purified with the exception of the protease cleavage step. Cerulean-Runt domain fusion protein (Runx1 41-190) ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862DTNPubMed
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM31179(thiazol-2-amine, 9)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+3nMAssay Description:His6-CBFbeta (1-141) was expressed and purified with the exception of the protease cleavage step. Cerulean-Runt domain fusion protein (Runx1 41-190) ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862DTNPubMed
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29658(MLS000557330 | N-[3-Cyano-1-furan-2-ylmethyl-8-met...)copy SMILEScopy InChI
Affinity DataIC50: 6.54E+3nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72FSXPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29658(MLS000557330 | N-[3-Cyano-1-furan-2-ylmethyl-8-met...)copy SMILEScopy InChI
Affinity DataIC50: 6.54E+3nMpH: 7.4 T: 2°CAssay Description:This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1H7PPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29639((4E)-3-methyl-4-[[3-[(2-methyl-4-oxidanyl-phenyl)a...)copy SMILEScopy InChI
Affinity DataIC50: 7.08E+3nMpH: 7.4 T: 2°CAssay Description:This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1H7PPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29639((4E)-3-methyl-4-[[3-[(2-methyl-4-oxidanyl-phenyl)a...)copy SMILEScopy InChI
Affinity DataIC50: 7.08E+3nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72FSXPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29643((6aS)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)copy SMILEScopy InChI
Affinity DataIC50: 7.12E+3nMpH: 7.4 T: 2°CAssay Description:This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1H7PPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29643((6aS)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)copy SMILEScopy InChI
Affinity DataIC50: 7.12E+3nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72FSXPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29672(5-(2-keto-7-methoxy-4-propionyloxy-6-propyl-chrome...)copy SMILEScopy InChI
Affinity DataIC50: 7.94E+3nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72FSXPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29672(5-(2-keto-7-methoxy-4-propionyloxy-6-propyl-chrome...)copy SMILEScopy InChI
Affinity DataIC50: 7.94E+3nMpH: 7.4 T: 2°CAssay Description:This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1H7PPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29643((6aS)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)copy SMILEScopy InChI
Affinity DataIC50: 8.48E+3nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25D8Q6QPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29632(2-[2-(3-keto-1,2-benzothiazol-2-yl)thiazol-4-yl]ac...)copy SMILEScopy InChI
Affinity DataIC50: 8.58E+3nMpH: 7.4 T: 2°CAssay Description:This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1H7PPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29632(2-[2-(3-keto-1,2-benzothiazol-2-yl)thiazol-4-yl]ac...)copy SMILEScopy InChI
Affinity DataIC50: 8.58E+3nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72FSXPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM434073(US10562890, Compound Al-12-126)copy SMILEScopy InChI
Affinity DataIC50: 8.91E+3nMAssay Description:FRET assay can be used to effectively monitor the inhibition of CBF binding to the Runt domain of RUNX proteins (as well as for CBFβ-SMMHC bindi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DR2XWHUS Patent
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM31178(thiazol-2-amine, 8)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMpH: 7.5 T: 2°CAssay Description:For the FRET measurements, the Cerulean-Runt (Runx1 41-190) and Venus-CBFbeta (1-141) fusion proteins were dialyzed into FRET assay buffer. Protein c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862DTNPubMed
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM31175(thiazol-2-amine, 5)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMpH: 7.5 T: 2°CAssay Description:For the FRET measurements, the Cerulean-Runt (Runx1 41-190) and Venus-CBFbeta (1-141) fusion proteins were dialyzed into FRET assay buffer. Protein c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2862DTNPubMed
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29644((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)copy SMILEScopy InChI
Affinity DataIC50: 9.81E+3nMpH: 7.4 T: 2°CAssay Description:This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1H7PPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29644((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...)copy SMILEScopy InChI
Affinity DataIC50: 9.81E+3nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72FSXPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29668(2-(1-{[4-(2,5-Dimethyl-phenyl)-thiazol-2-yl]-hydra...)copy SMILEScopy InChI
Affinity DataIC50: 1.01E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72FSXPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29668(2-(1-{[4-(2,5-Dimethyl-phenyl)-thiazol-2-yl]-hydra...)copy SMILEScopy InChI
Affinity DataIC50: 1.01E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1H7PPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM576(1-Diphenylamino-pyrrole-2,5-dione | MLS000590474 |...)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25D8Q6QPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29685((3E)-3-(2-furanylmethylidene)-1,2-dihydrocyclopent...)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72FSXPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29685((3E)-3-(2-furanylmethylidene)-1,2-dihydrocyclopent...)copy SMILEScopy InChI
Affinity DataIC50: 1.04E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1H7PPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29684((3E)-3-(2-furanylmethylidene)-1,2-dihydrocyclopent...)copy SMILEScopy InChI
Affinity DataIC50: 1.06E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1H7PPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29684((3E)-3-(2-furanylmethylidene)-1,2-dihydrocyclopent...)copy SMILEScopy InChI
Affinity DataIC50: 1.06E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72FSXPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29666((9-Oxo-9H-acridin-10-yl)-acetic acid [1-(4-chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 1.16E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72FSXPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29666((9-Oxo-9H-acridin-10-yl)-acetic acid [1-(4-chloro-...)copy SMILEScopy InChI
Affinity DataIC50: 1.16E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1H7PPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29661(2-Amino-1-furan-2-ylmethyl-1H-pyrrolo[2,3-b]quinox...)copy SMILEScopy InChI
Affinity DataIC50: 1.17E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2T72FSXPCBioAssay
TargetRunt-related transcription factor 1(Homo sapiens (Human))
University of Virginia at Charlottesville

LigandPNGBDBM29661(2-Amino-1-furan-2-ylmethyl-1H-pyrrolo[2,3-b]quinox...)copy SMILEScopy InChI
Affinity DataIC50: 1.17E+4nMpH: 7.4 T: 2°CAssay Description:This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DV1H7PPCBioAssay
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