Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Thiopurine S-methyltransferase'
TargetThiopurine S-methyltransferase(Homo sapiens (Human))
BioKin Ltd.

Curated by ChEMBL
LigandPNGBDBM50530712(CHEMBL4591248)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human TPMT expressed in Escherichia coli assessed as reduction in SAH level using 6-mercaptopurine as substrate in presence of SAM incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50RDJPubMed
TargetThiopurine S-methyltransferase(Homo sapiens (Human))
BioKin Ltd.

Curated by ChEMBL
LigandPNGBDBM50530712(CHEMBL4591248)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human TPMT expressed in Escherichia coli assessed as reduction in SAH level using 6-mercaptopurine as substrate in presence of SAM incu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50RDJPubMed
TargetThiopurine S-methyltransferase(Homo sapiens (Human))
BioKin Ltd.

Curated by ChEMBL
LigandPNGBDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)copy SMILEScopy InChI
Affinity DataKd:  1.00E+4nMAssay Description:Binding affinity to thiopurine methyltransferase (unknown origin) by NMR analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8GH3PubMed