Compile Data Set for Download or QSAR
Found 217 Enz. Inhib. hit(s) with Target = 'Transcription initiation factor TFIID subunit 1 [1381-1497]'
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346517(US10202378, Example 121 | o-tolylmethyl 4-(3-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346549(US10202378, Example 153 | cyclohexylmethyl 4-(3-hy...)copy SMILEScopy InChI
Affinity DataIC50: 85.3nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346546(2,2-dimethylpropyl 4-(3-hydroxy-3-methyl-but-1-yny...)copy SMILEScopy InChI
Affinity DataIC50: 93.6nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346501(8-quinolylmethyl 4-(3-cyclopropyl-3-hydroxy-but-1-...)copy SMILES
Affinity DataIC50: 93.9nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346544(US10202378, Example 148 | cyclopentylmethyl 4-(3-h...)copy SMILEScopy InChI
Affinity DataIC50: 96.8nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346545(2-methylbutyl 4-(3-hydroxy-3-methyl-but-1-ynyl)-2,...)copy SMILES
Affinity DataIC50: 101nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346512(US10202378, Example 116 | [2-(trifluoromethyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 105nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346492(3-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-4-(3-cyclopr...)copy SMILES
Affinity DataIC50: 108nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346554(US10202378, Example 158 | isobutyl 4-[(3R)-3-hydro...)copy SMILES
Affinity DataIC50: 112nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346506((2-cyanophenyl)methyl 4-(3-hydroxy-3-methyl-but-1-...)copy SMILEScopy InChI
Affinity DataIC50: 116nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346447(US10202378, Example 60 | ethyl 4-[2-(3-aminophenyl...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346522(US10202378, Example 126 | isobutyl 4-(3-cyclopropy...)copy SMILES
Affinity DataIC50: 123nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346509((2-methoxyphenyl)methyl-4-(3-hydroxy-3-methyl-but-...)copy SMILEScopy InChI
Affinity DataIC50: 123nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346513(US10202378, Example 117 | p-tolylmethyl 4-(3-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 128nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346556(US10202378, Example 160 | isobutyl 4-(3-hydroxy-3-...)copy SMILES
Affinity DataIC50: 130nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346425(US10202378, Example 38 | ethyl 4-[(3R)-3-hydroxy-3...)copy SMILES
Affinity DataIC50: 136nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346575(4-(3-cyclopropyl-3-hydroxy-but-1-ynyl)-3-(5-isobut...)copy SMILES
Affinity DataIC50: 137nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346422(US10202378, Example 35 | ethyl 4-(4-cyano-3-hydrox...)copy SMILES
Affinity DataIC50: 139nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346515((2-fluorophenyl)methyl 4-(3-hydroxy-3-methyl-but-1...)copy SMILEScopy InChI
Affinity DataIC50: 145nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346404(US10202378, Example 19 | ethyl 4-[3-(3-cyanophenyl...)copy SMILES
Affinity DataIC50: 146nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346550(US10202378, Example 154 | isobutyl 4-(4-cyano-3-hy...)copy SMILES
Affinity DataIC50: 150nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346499(Benzyl 4-(3-hydroxy-3-methyl-but-1-ynyl)-2,6-dimet...)copy SMILEScopy InChI
Affinity DataIC50: 151nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346464(US10202378, Example 77 | US10202378, Example 92a |...)copy SMILES
Affinity DataIC50: 154nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346538(1,2-dimethylpropyl 4-[3-hydroxy-3-(5-methylisoxazo...)copy SMILES
Affinity DataIC50: 160nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346502(US10202378, Example 106 | [3-(hydroxymethyl)phenyl...)copy SMILES
Affinity DataIC50: 166nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346514(US10202378, Example 118 | m-tolylmethyl 4-(3-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 167nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346428(US10202378, Example 41 | ethyl 2,6-dimethyl-7-oxo-...)copy SMILES
Affinity DataIC50: 171nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346528(US10202378, Example 132 | isobutyl 4-(3-hydroxy-3-...)copy SMILEScopy InChI
Affinity DataIC50: 173nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346476(US10202378, Example 89 | US10202378, Example 93a |...)copy SMILES
Affinity DataIC50: 176nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346441(US10202378, Example 54 | isobutyl 4-[(3R)-3-hydrox...)copy SMILES
Affinity DataIC50: 179nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346408(US10202378, Example 23 | ethyl 4-(3-hydroxy-3-meth...)copy SMILES
Affinity DataIC50: 182nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346488(4-(3-cyclopropyl-3-hydroxy-but-1-ynyl)-2,6-dimethy...)copy SMILES
Affinity DataIC50: 182nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346460(US10202378, Example 73 | US10202378, Example 91a |...)copy SMILES
Affinity DataIC50: 184nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346592(US10202378, Example 197 | ethyl 4-[3-(3-carbamoylp...)copy SMILES
Affinity DataIC50: 185nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346496(US10202378, Example 100 | ethyl 2,6-dimethyl-7-oxo...)copy SMILES
Affinity DataIC50: 189nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346484(3-(5-isopropyl-1,3,4-oxadiazol-2-yl)-2,6-dimethyl-...)copy SMILES
Affinity DataIC50: 192nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346450(US10202378, Example 63 | ethyl 4-[2-(3-hydroxyphen...)copy SMILEScopy InChI
Affinity DataIC50: 195nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346577(4-(3-cyclopropyl-3-hydroxy-but-1-ynyl)-3-(5-ethyl-...)copy SMILES
Affinity DataIC50: 199nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346490(4-(3-cyclopropyl-3-hydroxy-but-1-ynyl)-3-[5-[(dime...)copy SMILES
Affinity DataIC50: 205nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346388(US10202378, Example 3 | ethyl 4-[3-[4-(dimethylami...)copy SMILES
Affinity DataIC50: 209nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346456(US10202378, Example 69 | ethyl 4-[(3R)-3-hydroxy-3...)copy SMILES
Affinity DataIC50: 210nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346486(3-[5-[(dimethylamino)methyl]-1,3,4-oxadiazol-2-yl]...)copy SMILES
Affinity DataIC50: 211nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346401(US10202378, Example 16 | ethyl 4-(3-hydroxy-3-meth...)copy SMILES
Affinity DataIC50: 212nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346562(2-cyanoethyl 2,6-dimethyl-7-oxo-4-(4,4,4-trifluoro...)copy SMILES
Affinity DataIC50: 214nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346492(3-(5-tert-butyl-1,3,4-oxadiazol-2-yl)-4-(3-cyclopr...)copy SMILES
Affinity DataIC50: 216nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346420(US10202378, Example 33 | ethyl 4-[3-(3-fluoropheny...)copy SMILES
Affinity DataIC50: 218nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346547(1,1-dimethylpropyl 4-(3-hydroxy-3-methyl-but-1-yny...)copy SMILEScopy InChI
Affinity DataIC50: 221nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346505(US10202378, Example 109 | thiazol-2-ylmethyl 4-(3-...)copy SMILES
Affinity DataIC50: 222nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346530((2-cyano-1,1-dimethyl-ethyl)-4-(3-cyclopropyl-3-hy...)copy SMILES
Affinity DataIC50: 222nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
TargetTranscription initiation factor TFIID subunit 1 [1381-1497](Homo sapiens (human))
GENENTECH, INC.; CONSTELLATION PHARMACEUTICALS, INC.

US Patent
LigandPNGBDBM346431(US10202378, Example 44 | ethyl 2,6-dimethyl-7-oxo-...)copy SMILES
Affinity DataIC50: 226nMAssay Description:His/Flag epitope tagged TAF1-BD11381-1497 was cloned, expressed, and purified to homogeneity. TAF1-BD binding and inhibition was assessed by monitori...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22B9149US Patent
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