Compile Data Set for Download or QSAR
Found 419 Enz. Inhib. hit(s) with Target = 'Uracil nucleotide/cysteinyl leukotriene receptor'
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50004952(3-(2-Carboxy-ethyl)-4,6-dichloro-1H-indole-2-carbo...)copy SMILEScopy InChI
Affinity DataKi:  1.21E+3nMAssay Description:Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by homologous competition binding assay in presence o...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445P0DPubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50458837(CHEMBL4206497)copy SMILEScopy InChI
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9ZWJPubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50010475(GAVESTINEL | GV-150526X)copy SMILEScopy InChI
Affinity DataKi:  1.63E+3nMAssay Description:Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by heterologous competition binding assayMore data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445P0DPubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50004952(3-(2-Carboxy-ethyl)-4,6-dichloro-1H-indole-2-carbo...)copy SMILEScopy InChI
Affinity DataKi:  2.32E+3nMAssay Description:Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445P0DPubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50004952(3-(2-Carboxy-ethyl)-4,6-dichloro-1H-indole-2-carbo...)copy SMILEScopy InChI
Affinity DataKi:  2.45E+3nMAssay Description:Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9ZWJPubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50023198(8-[4-(4-phenylbutyloxy)benzoyl]amino-2-(tetrazol-5...)copy SMILEScopy InChI
Affinity DataKi:  4.06E+3nMAssay Description:Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by heterologous competition binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445P0DPubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50052024(CHEMBL787 | montelukast)copy SMILEScopy InChI
Affinity DataKi:  6.54E+3nMAssay Description:Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO-K1 cell membranes after 60 mins by heterologous competition binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445P0DPubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50458838(CHEMBL4215280)copy SMILEScopy InChI
Affinity DataKi:  1.31E+4nMAssay Description:Displacement of [3H]PSB-12150 from human GPR17 expressed in CHO cell membranes after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9ZWJPubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50318031(CHEMBL1097279 | cangrelor)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Antagonist activity at human GPR17 expressed in human 1321N1 cells assessed as inhibition of UDP-glucose-induced [35S]GTPgammaS binding after 30 mins...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9WFWPubMed
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646601(6-chloro-7- (difluoromethylthio)-N-[5-(2- fluoroet...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646556(6-chloro-N-[5-(3- fluoropropyl)-4,6-dimethoxy- pyr...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646694(6-chloro-N-[5-(2,2- difluoroethyl)-4-methoxy- pyri...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646555(6-chloro-N-[5-(2,2- difluoroethyl)-4,6-dimethoxy- ...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646738(6-bromo-N-[5-(2-cyanoethyl)- 4,6-dimethoxy-pyrimid...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646563(6-chloro-N-[5-(2-cyanoethyl)- 4,6-dimethoxy-pyrimi...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646588(6-bromo-N-[5-(2-cyanoethyl)- 4,6-dimethoxy-pyrimid...)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646548(6-chloro-N-[5-(2- fluoroethoxy)-4,6-dimethoxy- pyr...)copy SMILES
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646598(N-[5-(2-cyanoethyl)-4,6- dimethoxy-pyrimidin-2-yl]...)copy SMILES
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646655(6-bromo-N-(4,6-dimethoxy-5- methyl-pyrimidin-2-yl)...)copy SMILES
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646516(6-chloro-N-[5-(3- fluoropropyl)-4-methoxy- pyrimid...)copy SMILES
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646602(6-chloro-N-[5-(2-cyanoethyl)- 4,6-dimethoxy-pyrimi...)copy SMILES
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646557(6-chloro-N-[5-(3,3- difluoropropyl)-4,6- dimethoxy...)copy SMILES
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646551(N-(5-allyl-4,6-dimethoxy- pyrimidin-2-yl)-6-chloro...)copy SMILES
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646554(6-chloro-N-[5-(2-fluoroethyl)- 4,6-dimethoxy-pyrim...)copy SMILES
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646778(US20240025883, Example 283)copy SMILES
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646606(6-bromo-N-[5-(2,2- difluoroethyl)-4,6-dimethoxy- p...)copy SMILES
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646681(6-chloro-N-[5-(2,2- difluoroethyl)-4-methoxy- pyri...)copy SMILES
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646636(7-bromo-6-chloro-N-[5-(2- fluoroethoxy)-4-methoxy-...)copy SMILES
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646564(6-chloro-N-(5-cyclopropyl- 4,6-dimethoxy-pyrimidin...)copy SMILES
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646597(N-[5-(2,2-difluoroethoxy)-4,6- dimethoxy-pyrimidin...)copy SMILES
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646600(6-chloro-N-[5-(2-cyanoethyl)- 4-methoxy-pyrimidin-...)copy SMILES
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646760(6-chloro-N-[5- (cyanomethoxy)-4,6- dimethoxy-pyrim...)copy SMILES
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646713(6-chloro-N-[5-(2-cyanoethyl)- 4,6-dimethoxy-pyrimi...)copy SMILES
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646731(N-[5-(2,2-difluoroethyl)-4,6- dimethoxy-pyrimidin-...)copy SMILES
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646747(N-[5-(2-cyanoethyl)-4,6- dimethoxy-pyrimidin-2-yl]...)copy SMILES
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646702(6-chloro-N-[5-(3,3- difluoropropyl)-4-methoxy- pyr...)copy SMILES
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646667(US20240025883, Example 172)copy SMILES
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646607(6-bromo-N-[5-(3,3- difluoropropyl)-4,6- dimethoxy-...)copy SMILES
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646616(6-chloro-N-[5-(3,3- difluoropropyl)-4,6- dimethoxy...)copy SMILES
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646739(6-bromo-N-[5- (cyanomethoxy)-4,6- dimethoxy-pyrimi...)copy SMILES
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646729(6-chloro-N-[5-(2,2- difluoroethyl)-4-methoxy- pyri...)copy SMILES
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646691(6-bromo-N-[5-(2,2- difluoroethyl)-4-methoxy- pyrim...)copy SMILES
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646549(6-chloro-N-[5-(2,2- difluoroethoxy)-4,6- dimethoxy...)copy SMILES
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646712(6-chloro-N-[5-(2,2- difluoroethyl)-4,6-dimethoxy- ...)copy SMILES
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646553(6-chloro-N-(4,6-dimethoxy-5- propyl-pyrimidin-2-yl...)copy SMILES
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646550(6-chloro-N-[4,6-dimethoxy-5- (1,1,2- trifluoroetho...)copy SMILES
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646682(6-chloro-N-[5-(3,3- difluoropropyl)-4-methoxy- pyr...)copy SMILES
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646714(6-chloro-N-[5- (cyanomethoxy)-4,6- dimethoxy-pyrim...)copy SMILES
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646705(6,7-dichloro-N-[5-(2,2- difluoroethyl)-4-methoxy- ...)copy SMILES
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetUracil nucleotide/cysteinyl leukotriene receptor(Homo sapiens (Human))
University of Bonn

Curated by ChEMBL
LigandPNGBDBM646587(6-bromo-N-[5-(2,2- difluoroethoxy)-4,6- dimethoxy-...)copy SMILES
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
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