Compile Data Set for Download or QSAR
Found 546 Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor A'
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50003017(CHEMBL3234202)copy SMILEScopy InChI
Affinity DataIC50: 0.120nMAssay Description:Inhibition of VEGF-A production in human HCT116 cells after 12 hrs by alphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154JKDPubMed
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50002930(CHEMBL3234200)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMAssay Description:Inhibition of VEGF-A production in human HCT116 cells after 12 hrs by alphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154JKDPubMed
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50002918(Apratoxin S4)copy SMILEScopy InChI
Affinity DataIC50: 0.320nMAssay Description:Inhibition of VEGF-A production in human HCT116 cells after 12 hrs by alphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154JKDPubMed
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM50002932(CHEMBL3234201)copy SMILEScopy InChI
Affinity DataIC50: 0.470nMAssay Description:Inhibition of VEGF-A production in human HCT116 cells after 12 hrs by alphaLISA assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2154JKDPubMed
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282581(4-Bromo-5-(3-chloro-5-fluorophenoxy)-2,2-difluoro-...)copy SMILEScopy InChI
Affinity DataIC50: 2nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282584(4-Chloro-5-(3-chloro-5-fluorophenoxy)-2,2-difluoro...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282572((R)-3-((4-(difluoromethyl)-2,2-difluoro-3-hydroxy-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282702((R)-3-((4-(Difluoromethyl)-2,2-difluoro-3-hydroxy-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282689(US9884843, Compound 33)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282686(US9884843, Compound 30)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282682(3-((3-Amino-4-(difluoromethyl)-2,2-difluoro-1,1- d...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282632(5-(3-Chloro-5-fluorophenoxy)-4-(difluoromethyl)- 2...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282656(4-(Difluoromethyl)-5-(3,5-difluorophenoxy)-2,2- di...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282634(3-Amino-4-(difluoromethyl)-5-(3,5- difluorophenoxy...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282632(5-(3-Chloro-5-fluorophenoxy)-4-(difluoromethyl)- 2...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282598(5-(3-Chloro-5-fluorophenoxy)-2,2-difluoro-3- hydro...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282713((R)-4-Bromo-5-(3-chloro-5-fluoro-phenoxy)-2,2- dif...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282761(5-(3-cyano-5-fluoro-phenoxy)-2,2-difluoro-3- hydro...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282572((R)-3-((4-(difluoromethyl)-2,2-difluoro-3-hydroxy-...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM25115(3-[(4-bromo-2,6-difluorophenyl)methoxy]-5-({[4-(py...)copy SMILEScopy InChI
Affinity DataIC50: 5.27nMAssay Description:Inhibition of VEGF-stimulated VEGFR-2 autophosphorylation in intact cells.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BK1B77US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282564((R)-3-((4-bromo-2,2-difluoro-3-hydroxy-1,1-dioxido...)copy SMILEScopy InChI
Affinity DataIC50: 7nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282768((3R)-5-(3-cyano-5-fluoro-phenoxy)-2,2- difluoro-3-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282741((R)-3-((4-chloro-2,2-difluoro-3-hydroxy-1,1-dioxid...)copy SMILEScopy InChI
Affinity DataIC50: 11nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282750(US9884843, Compound 94)copy SMILEScopy InChI
Affinity DataIC50: 11nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282685(3-((4-(Difluoromethyl)-2,2-difluoro-3-hydroxy-1,1-...)copy SMILEScopy InChI
Affinity DataIC50: 14nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282597(US9884843, Compound 13)copy SMILEScopy InChI
Affinity DataIC50: 15nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282740((R)-3-((4-bromo-2,2-difluoro-3-hydroxy-1,1-dioxido...)copy SMILEScopy InChI
Affinity DataIC50: 17nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282707(US9884843, Compound 51)copy SMILEScopy InChI
Affinity DataIC50: 20nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282746((R)-4-(Difluoromethyl)-5-(3,4-difluorophenoxy)-2,2...)copy SMILEScopy InChI
Affinity DataIC50: 24nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282708(4-(Difluoromethyl)-5-(3,5-difluorophenoxy)-2,2- di...)copy SMILEScopy InChI
Affinity DataIC50: 29nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282711((R)-3-Amino-4-(difluoromethyl)-5-(3,5- difluorophe...)copy SMILEScopy InChI
Affinity DataIC50: 33nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282745((R)-3-((4-(difluoromethyl)-2,2-difluoro-3-hydroxy-...)copy SMILEScopy InChI
Affinity DataIC50: 34nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282685(3-((4-(Difluoromethyl)-2,2-difluoro-3-hydroxy-1,1-...)copy SMILEScopy InChI
Affinity DataIC50: 34nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282756(5-(3,5-Difluorophenoxy)-2,2-difluoro-3- hydroxy-3-...)copy SMILEScopy InChI
Affinity DataIC50: 41nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282583(US9884843, Compound 10)copy SMILEScopy InChI
Affinity DataIC50: 45nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282753(US9884843, Compound 97)copy SMILEScopy InChI
Affinity DataIC50: 46nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282570((3R)-5-(3-chloro-5-fluoro-phenoxy)-3-hydroxy-1,1- ...)copy SMILEScopy InChI
Affinity DataIC50: 47nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282736(US9884843, Compound 80)copy SMILEScopy InChI
Affinity DataIC50: 57nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282708(4-(Difluoromethyl)-5-(3,5-difluorophenoxy)-2,2- di...)copy SMILEScopy InChI
Affinity DataIC50: 59nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282719(3-((4-Ethynyl-2,2-difluoro-3-hydroxy-1,1-dioxido- ...)copy SMILEScopy InChI
Affinity DataIC50: 59nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282715(US9884843, Compound 59)copy SMILEScopy InChI
Affinity DataIC50: 60nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282578(US9884843, Compound 7)copy SMILEScopy InChI
Affinity DataIC50: 61nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282772((3R)-4-bromo-5-(3-bromo-5-fluoro-phenoxy)- 2,2-dif...)copy SMILEScopy InChI
Affinity DataIC50: 63nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282737(US9884843, Compound 81)copy SMILEScopy InChI
Affinity DataIC50: 67nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282697((R)-3-((3-Amino-4-(difluoromethyl)-2,2-difluoro-1,...)copy SMILEScopy InChI
Affinity DataIC50: 69nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282747(US9884843, Compound 91)copy SMILEScopy InChI
Affinity DataIC50: 72nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282677(US9884843, Compound 24)copy SMILEScopy InChI
Affinity DataIC50: 77nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282754(4-Bromo-5-(3,5-difluorophenoxy)-2,2- difluoro-3-hy...)copy SMILEScopy InChI
Affinity DataIC50: 83nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282698(3-((2,2-Difluoro-4-(fluoromethyl)-3-hydroxy-1,1- d...)copy SMILEScopy InChI
Affinity DataIC50: 86nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
TargetVascular endothelial growth factor A(Homo sapiens (Human))
University of Florida

Curated by ChEMBL
LigandPNGBDBM282599(US9884843, Compound 15)copy SMILEScopy InChI
Affinity DataIC50: 100nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HQ41Z0US Patent
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