Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Actin [R335K]'
TargetActin [R335K](Baker's yeast)
Novartis Pharma AG

LigandPNGBDBM65515(76343-93-6 | LAT-A | LatA | Latrunculin A)copy SMILEScopy InChI
Affinity DataIC50: 40nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
TargetActin [R335K](Baker's yeast)
Novartis Pharma AG

LigandPNGBDBM65506(CHEBI:80062 | Chivosazole F | SCHEMBL1889389)copy SMILEScopy InChI
Affinity DataIC50: 270nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B00MPPubMed
TargetActin [R335K](Baker's yeast)
Novartis Pharma AG

LigandPNGBDBM65516(CHEBI:84382 | CHEMBL2426321 | Chondramide C)copy SMILEScopy InChI
Affinity DataIC50: 1.51E+4nMT: 2°CAssay Description:Saturated ACT1 wild type (WT) as well as engineered ACT1 R183K (R183K) and ACT1 R335K (R335K) cultures were adjusted to 10 OD600 and 3 uL of serial 1...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25B00MPPubMed