Compile Data Set for Download or QSAR
Found 89 Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor/Nucleophosmin'
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558033(CHEMBL4762256)copy SMILES
Affinity DataIC50: 3nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in human KARPAS-299 cells assessed as reduction in cell growthMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558033(CHEMBL4762256)copy SMILES
Affinity DataIC50: 6nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558029(CHEMBL4762861)copy SMILES
Affinity DataIC50: 7nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in human KARPAS-299 cells assessed as reduction in cell growthMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558032(CHEMBL4798141)copy SMILES
Affinity DataIC50: 13nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM107057(US8592432, 34)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM107057(US8592432, 34)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in human KARPAS-299 cells assessed as reduction in cell growthMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50436850(CERITINIB | CHEMBL2403108 | LDK378 | US10053458, C...)copy SMILEScopy InChI
Affinity DataIC50: 26nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50393620(CHEMBL2158531)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of human NPM-ALK phosphorylation using 4-MeUP substrate by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73FV3PubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM107057(US8592432, 34)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition NMP-ALK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558034(CHEMBL4791252)copy SMILES
Affinity DataIC50: 33nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558029(CHEMBL4762861)copy SMILES
Affinity DataIC50: 38nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50393610(CHEMBL2158527)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of human NPM-ALK phosphorylation using 4-MeUP substrate by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73FV3PubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM107097(US8592432, 83)copy SMILEScopy InChI
Affinity DataIC50: 47nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558035(CHEMBL4779222)copy SMILES
Affinity DataIC50: 47nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50353048(CHEMBL1822527)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of NPM/ALK phosphorylation in human KARPAS299 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ331FPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Inhibition of NPM/ALK (unknown origin) transfected in mouse BAF3 cells assessed as cell growth inhibition after 72 hrs by [3H]-thymidine incorporatio...More data for this Ligand-Target Pair
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50393616(CHEMBL2158525)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of human NPM-ALK phosphorylation using 4-MeUP substrate by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73FV3PubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50353046(CHEMBL1822525)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of NPM/ALK phosphorylation in human KARPAS299 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ331FPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50353046(CHEMBL1822525)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Inhibition of human NPM-ALK phosphorylation using 4-MeUP substrate by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73FV3PubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50158419(CHEMBL3734798)copy SMILEScopy InChI
Affinity DataIC50: 64nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in human KARPAS-299 cells assessed as reduction in cell growthMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50353044(CHEMBL1822523)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of NPM/ALK phosphorylation in human KARPAS299 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ331FPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50393613(CHEMBL2158518)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of human NPM-ALK phosphorylation using 4-MeUP substrate by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73FV3PubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50393614(CHEMBL2158529)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of human NPM-ALK phosphorylation using 4-MeUP substrate by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73FV3PubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50393615(CHEMBL2158526)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of human NPM-ALK phosphorylation using 4-MeUP substrate by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73FV3PubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50393617(CHEMBL2158519)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of human NPM-ALK phosphorylation using 4-MeUP substrate by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73FV3PubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50353042(CHEMBL1822521)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of NPM/ALK phosphorylation in human KARPAS299 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ331FPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50393619(CHEMBL2158530)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of human NPM-ALK phosphorylation using 4-MeUP substrate by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73FV3PubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50393624(CHEMBL2158516)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of human NPM-ALK phosphorylation using 4-MeUP substrate by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73FV3PubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50353047(CHEMBL1822526)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of NPM/ALK phosphorylation in human KARPAS299 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ331FPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50353043(CHEMBL1822522)copy SMILEScopy InChI
Affinity DataIC50: 85nMAssay Description:Inhibition of NPM/ALK phosphorylation in human KARPAS299 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ331FPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50393609(CHEMBL2158511)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human NPM-ALK phosphorylation using 4-MeUP substrate by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73FV3PubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50361205(CHEMBL1934334)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human NPM-ALK phosphorylation using 4-MeUP substrate by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73FV3PubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50393618(CHEMBL2158528)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of human NPM-ALK phosphorylation using 4-MeUP substrate by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73FV3PubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50353040(CHEMBL1822519)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of NPM/ALK phosphorylation in human KARPAS299 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ331FPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50353041(CHEMBL1822520)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of NPM/ALK phosphorylation in human KARPAS299 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ331FPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50393612(CHEMBL2158586)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of human NPM-ALK phosphorylation using 4-MeUP substrate by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73FV3PubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558028(CHEMBL4755518)copy SMILES
Affinity DataIC50: 150nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50393611(CHEMBL2158515)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of human NPM-ALK phosphorylation using 4-MeUP substrate by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73FV3PubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 150nMAssay Description:Inhibition of NPM/ALK L256T mutant kinase activity in BaF3 cells by radioenzymatic assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4416PubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50158419(CHEMBL3734798)copy SMILEScopy InChI
Affinity DataIC50: 151nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50393625(CHEMBL2158521)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human NPM-ALK phosphorylation using 4-MeUP substrate by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73FV3PubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50393608(CHEMBL2158587)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of human NPM-ALK phosphorylation using 4-MeUP substrate by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73FV3PubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM4552(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of NPM/ALK L256T mutant autophosphorylation activity in BaF3 cells by antiphosphotyrosine immunoblotting assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21Z4416PubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50353045(CHEMBL1822524)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of NPM/ALK phosphorylation in human KARPAS299 cells by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VQ331FPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50393623(CHEMBL2158513)copy SMILEScopy InChI
Affinity DataIC50: 250nMAssay Description:Inhibition of human NPM-ALK phosphorylation using 4-MeUP substrate by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73FV3PubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558031(CHEMBL4780490)copy SMILES
Affinity DataIC50: 328nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in human KARPAS-299 cells assessed as reduction in cell growthMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50448037(CHEMBL3115500)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of NPM/ALK (unknown origin) transfected in mouse BAF3 cells assessed as cell growth inhibition after 72 hrs by [3H]-thymidine incorporatio...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NZ894QPubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50575343(CHEMBL4858720)copy SMILES
Affinity DataIC50: 370nMAssay Description:Inhibition of NPM-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 48 hrs by cell prolife...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23R0XP8PubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50393622(CHEMBL2158512)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Inhibition of human NPM-ALK phosphorylation using 4-MeUP substrate by cell based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73FV3PubMed
TargetALK tyrosine kinase receptor/Nucleophosmin(Homo sapiens (Human))TBA
LigandPNGBDBM50558031(CHEMBL4780490)copy SMILES
Affinity DataIC50: 684nMAssay Description:Inhibition of NMP-ALK (unknown origin) expressed in mouse BaF3 cells assessed as reduction in cell proliferation incubated for 2 to 3 days by Bright-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XS603JPubMed
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