Compile Data Set for Download or QSAR
Found 452 Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor [L1196M]'
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM261689(US9708295, 30)copy SMILEScopy InChI
Affinity DataKi:  18.8nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GM899ZUS Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM261711(US9708295, 53)copy SMILEScopy InChI
Affinity DataKi:  32.1nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GM899ZUS Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM261686(US9708295, 27)copy SMILEScopy InChI
Affinity DataKi:  35.1nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GM899ZUS Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM243393(5-chloro-N4-2-(isopropylsulfonyl)phenyl)-N2-(7-met...)copy SMILEScopy InChI
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2ZH9US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM50116696(CHEMBL3608534 | US10053458, 52)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2ZH9US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM291934(US10100019, Example 4)copy SMILEScopy InChI
Affinity DataIC50: 0.850nMAssay Description:To measure the activity of the N2-(2-methoxyphenyl)pyrimidine derivative represented by formula 1 of the present invention to inhibit anaplastic lymp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VPTUS Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM448448(US10695347, Compound I-14)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CQ8US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM448449(US10695347, Compound I-15)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CQ8US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM448450(US10695347, Compound I-16)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CQ8US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM50116699(CHEMBL3608642 | US10053458, 53)copy SMILEScopy InChI
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2ZH9US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM50116680(CHEMBL3608523 | US10053458, 56)copy SMILEScopy InChI
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2ZH9US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM175253(US9115140, I-131)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:The reagents used have the following composition: Enzyme buffer (EB): 50 mM HEPES (pH: 7.0) (Sigma H7523), 100 mM NaCl (Sigma S7653), NaN.sub.3 at 0....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1BFXUS Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM448455(US10695347, Compound I-82)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CQ8US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM448458(US10695347, Compound I-86)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CQ8US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM448461(US10695347, Compound I-89)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CQ8US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM448465(US10695347, Compound I-95)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CQ8US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM448466(US10695347, Compound I-98)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CQ8US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM448468(US10695347, Compound I-102)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CQ8US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM448469(US10695347, Compound I-103)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CQ8US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM448473(US10695347, Compound I-111)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CQ8US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM448474(US10695347, Compound I-112)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CQ8US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM448475(US10695347, Compound I-113)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CQ8US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM448476(US10695347, Compound I-114)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CQ8US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM448477(US10695347, Compound I-115)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CQ8US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM448435(US10695347, Compound I-1)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CQ8US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM448436(US10695347, Compound I-2)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CQ8US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM448437(US10695347, Compound I-3)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CQ8US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM448442(US10695347, Compound I-8)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CQ8US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM448447(US10695347, Compound I-13)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:1× Kinase Buffer 50 mM HEPES. pH 7.5 0.0015% Brij-35 10 mM MgCl2 2 mM DTT 2) stop buffer 100 mM HEPES, pH 7...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M90CQ8US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM243388(5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(7-is...)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2ZH9US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM50116685(CHEMBL3608644 | US10053458, 54)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2ZH9US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM50116693(CHEMBL3608531 | US10053458, 51)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2ZH9US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM50116683(CHEMBL3608526 | US10053458, 49)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2ZH9US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM243386(5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(7-is...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2ZH9US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM291988(US10100019, Example 58)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:To measure the activity of the N2-(2-methoxyphenyl)pyrimidine derivative represented by formula 1 of the present invention to inhibit anaplastic lymp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VPTUS Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM243432(5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(6-me...)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2ZH9US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM291994(US10100019, Example 64)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:To measure the activity of the N2-(2-methoxyphenyl)pyrimidine derivative represented by formula 1 of the present invention to inhibit anaplastic lymp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VPTUS Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM291996(US10100019, Example 66)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:To measure the activity of the N2-(2-methoxyphenyl)pyrimidine derivative represented by formula 1 of the present invention to inhibit anaplastic lymp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VPTUS Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM291987(US10100019, Example 57)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:To measure the activity of the N2-(2-methoxyphenyl)pyrimidine derivative represented by formula 1 of the present invention to inhibit anaplastic lymp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VPTUS Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM291990(US10100019, Example 60)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:To measure the activity of the N2-(2-methoxyphenyl)pyrimidine derivative represented by formula 1 of the present invention to inhibit anaplastic lymp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VPTUS Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM291985(US10100019, Example 55)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:To measure the activity of the N2-(2-methoxyphenyl)pyrimidine derivative represented by formula 1 of the present invention to inhibit anaplastic lymp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VPTUS Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM199945(US9226923, 3)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:The inhibitory activities of compounds of Formula I were assay at Reaction Biology Corporation, One Great Valley Parkway, Malvern, Pa., USA. Human ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JQ0ZT5US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM291993(US10100019, Example 63)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:To measure the activity of the N2-(2-methoxyphenyl)pyrimidine derivative represented by formula 1 of the present invention to inhibit anaplastic lymp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VPTUS Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM243401(5-chloro-N4-(2-(isopropylsulfonyl)phenyl)-N2-(7-me...)copy SMILEScopy InChI
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZS2ZH9US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM175250(US9115140, I-118)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:The reagents used have the following composition: Enzyme buffer (EB): 50 mM HEPES (pH: 7.0) (Sigma H7523), 100 mM NaCl (Sigma S7653), NaN.sub.3 at 0....More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HX1BFXUS Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM193475(US9199944, 57)copy SMILEScopy InChI
Affinity DataIC50: 2nMT: 2°CAssay Description:In order to measure the inhibitory activity against ALK, a Grainer 96-well round type bottom plate was added with the compounds (2 μl) prepared ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J96558US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM193476(US9199944, 58)copy SMILEScopy InChI
Affinity DataIC50: 2nMT: 2°CAssay Description:In order to measure the inhibitory activity against ALK, a Grainer 96-well round type bottom plate was added with the compounds (2 μl) prepared ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J96558US Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM291998(US10100019, Example 69)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:To measure the activity of the N2-(2-methoxyphenyl)pyrimidine derivative represented by formula 1 of the present invention to inhibit anaplastic lymp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VPTUS Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM291997(US10100019, Example 68)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:To measure the activity of the N2-(2-methoxyphenyl)pyrimidine derivative represented by formula 1 of the present invention to inhibit anaplastic lymp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VPTUS Patent
TargetALK tyrosine kinase receptor [L1196M](Homo sapiens (Human))
CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD.; Centaurus Biopharma Co., Ltd.; LIANYUNGANG RUNZHONG PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM291999(US10100019, Example 70)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:To measure the activity of the N2-(2-methoxyphenyl)pyrimidine derivative represented by formula 1 of the present invention to inhibit anaplastic lymp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125VPTUS Patent
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