Compile Data Set for Download or QSAR
Found 770 Enz. Inhib. hit(s) with Target = 'Serine/threonine-protein kinase receptor R3'
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
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US Patent
LigandPNGBDBM160301(US9040691, 29)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160276(US9040691, 4)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160312(US9040691, 40 | US9040691, 41 | US9040691, 42)copy SMILEScopy InChI
Affinity DataIC50: 1.20nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160277(US9040691, 5)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM130909(US10683289, Example Staurosporine | US10927120, Co...)copy SMILEScopy InChI
Affinity DataIC50: 1.36nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TKVUS Patent
TargetSerine/threonine-protein kinase receptor R3(Mus musculus)
Massachusetts Institute of Technology

LigandPNGBDBM50262079(4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyri...)copy SMILEScopy InChI
Affinity DataIC50: 1.48nMMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9VGJPubMed
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160315(US9040691, 43)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160283(US9040691, 11)copy SMILEScopy InChI
Affinity DataIC50: 1.90nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160279(US9040691, 7)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160289(US9040691, 17)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160302(US9040691, 30)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160273(US9040691, 1)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Mus musculus)
Massachusetts Institute of Technology

LigandPNGBDBM102618(LDN-212854)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1JKWPubMed
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160288(US9040691, 16)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160274(US9040691, 2)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160283(US9040691, 11)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:ALKl (Invitrogen, Carlsbad, CA, USA) kinase activity was measured at ProQinase GmbH ( Freiburg. Germany) in a radiometric assay using gamma-33P-ATP a...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160309(US9040691, 37)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:ALKl (Invitrogen, Carlsbad, CA, USA) kinase activity was measured at ProQinase GmbH ( Freiburg. Germany) in a radiometric assay using gamma-33P-ATP a...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160312(US9040691, 40 | US9040691, 41 | US9040691, 42)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160312(US9040691, 40 | US9040691, 41 | US9040691, 42)copy SMILEScopy InChI
Affinity DataIC50: 3.5nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Mus musculus)
Massachusetts Institute of Technology

LigandPNGBDBM102619(K02288a | US10688093, Compound 382_0087_0284 | US1...)copy SMILEScopy InChI
Affinity DataIC50: 3.65nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZW1JKWPubMed
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160316(US9040691, 44)copy SMILEScopy InChI
Affinity DataIC50: 3.80nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM143311(US10017516, Compound 11 | US9682983, 11)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE® Ultra ULight¿ technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4N3RUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM161920(US10017516, Compound 53 | US9682983, 52 | US968298...)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE® Ultra ULight¿ technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4N3RUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM143311(US10017516, Compound 11 | US9682983, 11)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P12CNUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM111123(US10017516, Compound 2 | US9682983, 2)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P12CNUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160275(US9040691, 3)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160304(US9040691, 32)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160303(US9040691, 31)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160310(US9040691, 38)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:ALKl (Invitrogen, Carlsbad, CA, USA) kinase activity was measured at ProQinase GmbH ( Freiburg. Germany) in a radiometric assay using gamma-33P-ATP a...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160285(US9040691, 13)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160306(US9040691, 34)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160280(US9040691, 35 | US9040691, 36 | US9040691, 8)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM130912(US8822500, [1])copy SMILEScopy InChI
Affinity DataIC50: 4.70nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TKVUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM50560477(CHEMBL4742906)copy SMILES
Affinity DataIC50: 5nMAssay Description:Inhibition of human ALK1 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7NDJPubMed
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160286(US9040691, 14)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160281(US9040691, 9)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160311(US9040691, 39)copy SMILEScopy InChI
Affinity DataIC50: 5.70nMAssay Description:ALKl (Invitrogen, Carlsbad, CA, USA) kinase activity was measured at ProQinase GmbH ( Freiburg. Germany) in a radiometric assay using gamma-33P-ATP a...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM111123(US10017516, Compound 2 | US9682983, 2)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMpH: 7.5Assay Description:Specifically, compounds were assayed using LANCE® Ultra ULight¿ technology (Perkin Elmer) against human ALK1-6 enzymes (ALK1: Life Technologies, ALK2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4N3RUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM111123(US10017516, Compound 2 | US9682983, 2)copy SMILEScopy InChI
Affinity DataIC50: 5.80nMAssay Description:Compounds were assessed in ALK1-6 enzymatic assays. Specifically, compounds were assayed using LANCE® Ultra ULight technology (Perkin Elmer) against ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20P12CNUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160284(US9040691, 12)copy SMILEScopy InChI
Affinity DataIC50: 5.90nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM518186(US11111247, Example 17)copy SMILES
Affinity DataIC50: 5.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78K72PubMed
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160279(US9040691, 7)copy SMILEScopy InChI
Affinity DataIC50: 6.70nMAssay Description:ALKl (Invitrogen, Carlsbad, CA, USA) kinase activity was measured at ProQinase GmbH ( Freiburg. Germany) in a radiometric assay using gamma-33P-ATP a...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160280(US9040691, 35 | US9040691, 36 | US9040691, 8)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMAssay Description:ALKl (Invitrogen, Carlsbad, CA, USA) kinase activity was measured at ProQinase GmbH ( Freiburg. Germany) in a radiometric assay using gamma-33P-ATP a...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM160282(US9040691, 10)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:In vitro enzyme inhibition using scintillation of incorporated radio label (flashplate assay). Test compounds diluted in DMSO are mixed with a suitab...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7F1TUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM130919(US8822500, [18])copy SMILEScopy InChI
Affinity DataIC50: 9.16nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TKVUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM130910(US8822500, [4])copy SMILEScopy InChI
Affinity DataIC50: 9.81nMpH: 7.5Assay Description:Compounds to be tested were dissolved in 100% DMSO in a range of concentrations from 10-8 to 10-3 M including negative control (DMSO), then diluted w...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TKVUS Patent
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM518194(US11111247, Example 24)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78K72PubMed
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM518173(US11111247, Example 9)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78K72PubMed
TargetSerine/threonine-protein kinase receptor R3(Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH

US Patent
LigandPNGBDBM50596220(CHEMBL5205781)copy SMILES
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JS9VGJPubMed
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