Compile Data Set for Download or QSAR
Found 13 Enz. Inhib. hit(s) with Target = '5'-AMP-activated protein kinase subunit beta-2'
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)copy SMILEScopy InChI
Affinity DataIC50: 62nMMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50262685(6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-...)copy SMILEScopy InChI
Affinity DataIC50: 1.28E+3nMMore data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM237920(US9394285, 1)copy SMILEScopy InChI
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of recombinant human AMPK alpha2/beta2/gamma3 by using Cy5-labelled SAMS as substrate in presence of ATP by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PZ5BRCPubMed
Target5'-AMP-activated protein kinase subunit beta-2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50246120(CHEMBL4082745)copy SMILEScopy InChI
Affinity DataEC50:  35nMAssay Description:Agonist activity at human recombinant phosphorylated AMPK complex 12 alpha2/beta2/gamma3 expressed in baculovirus infected Sf21 cells assessed as pho...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2V69N0QPubMed
Target5'-AMP-activated protein kinase subunit beta-2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM238079(US9394285, 173)copy SMILEScopy InChI
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta2gamma3 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q242WTPubMed
Target5'-AMP-activated protein kinase subunit beta-2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM237920(US9394285, 1)copy SMILEScopy InChI
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta2gamma3 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q242WTPubMed
Target5'-AMP-activated protein kinase subunit beta-2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50244667(CHEMBL4105032)copy SMILEScopy InChI
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta2gamma3 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q242WTPubMed
Target5'-AMP-activated protein kinase subunit beta-2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50463100(CHEMBL4249790)copy SMILEScopy InChI
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta2gamma3 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q242WTPubMed
Target5'-AMP-activated protein kinase subunit beta-2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50463099(CHEMBL4246000)copy SMILEScopy InChI
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta2gamma3 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q242WTPubMed
Target5'-AMP-activated protein kinase subunit beta-2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50600528(CHEMBL5191686)copy SMILES
Affinity DataEC50:  1.30E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5KPRPubMed
Target5'-AMP-activated protein kinase subunit beta-2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50195479(CHEMBL3950376)copy SMILEScopy InChI
Affinity DataEC50: <5.00E+3nMAssay Description:Activation of human recombinant AMPK beta2 expressed in African green monkey COS7 cells or baculovirus infected insect cells assessed as increase in ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M67PHPubMed
Target5'-AMP-activated protein kinase subunit beta-2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50195534(CHEMBL3957286)copy SMILEScopy InChI
Affinity DataEC50:  4nMAssay Description:Activation of human recombinant AMPK alpha2/beta2/gamma3 expressed in African green monkey COS7 cells assessed as increase in biotinylated AAC (1 to ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25M67PHPubMed
Target5'-AMP-activated protein kinase subunit beta-2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50463101(CHEMBL4250253)copy SMILEScopy InChI
Affinity DataEC50: >4.00E+4nMAssay Description:Activation of full-length recombinant N-terminal His-tagged human AMPKalpha2beta2gamma3 expressed in Escherichia coli BL21 cells using Cy-5 SAMS pept...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Q242WTPubMed