Compile Data Set for Download or QSAR
Found 524 Enz. Inhib. hit(s) with Target = 'Monoacylglycerol lipase ABHD6'
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Bristol-Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50048620(CHEMBL3319620)copy SMILEScopy InChI
Affinity DataKi:  800nMAssay Description:Inhibition of ABHD6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RJ4MBDPubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Bristol-Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50048620(CHEMBL3319620)copy SMILEScopy InChI
Affinity DataKi:  800nMAssay Description:Inhibition of human ABHD6 expressed in HEK293T cell membranes assessed as reduction in glycerol production using 2-arachidonoyl glycerol substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SD4PubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Bristol-Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50048620(CHEMBL3319620)copy SMILEScopy InChI
Affinity DataKi:  800nMMore data for this Ligand-Target Pair
In DepthDetails
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Bristol-Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50048618(CHEMBL3319622)copy SMILEScopy InChI
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition of human ABHD6 expressed in HEK293T cell membranes assessed as reduction in glycerol production using 2-arachidonoyl glycerol substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SD4PubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Bristol-Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50048621(CHEMBL3319619)copy SMILEScopy InChI
Affinity DataKi:  1.83E+4nMAssay Description:Inhibition of human ABHD6 expressed in HEK293T cell membranes assessed as reduction in glycerol production using 2-arachidonoyl glycerol substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R49SD4PubMed
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute

LigandPNGBDBM26736(CHEMBL509860 | LY2183240 | N,N-dimethyl-5-[(4-phen...)copy SMILEScopy InChI
Affinity DataIC50: 0.0900nMpH: 7.4 T: 2°CAssay Description:Serine hydrolase targets were recombinantly expressed in COS-7 cells by transient transfection. IC50 values were obtained by competitive ABPP with F...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K26VXPubMed
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute

LigandPNGBDBM50010337(CHEMBL3263582)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by ABPP-SILAC-based LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FXRPubMed
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute

LigandPNGBDBM50010335(CHEMBL3263577)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by ABPP-SILAC-based LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FXRPubMed
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute

LigandPNGBDBM50010336(CHEMBL3263579)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by ABPP-SILAC-based LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FXRPubMed
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute

LigandPNGBDBM50010336(CHEMBL3263579)copy SMILEScopy InChI
Affinity DataIC50: 0.210nMAssay Description:In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by gel-based competitive ABPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FXRPubMed
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute

LigandPNGBDBM50010335(CHEMBL3263577)copy SMILEScopy InChI
Affinity DataIC50: 0.240nMAssay Description:In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by gel-based competitive ABPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FXRPubMed
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute

LigandPNGBDBM50010337(CHEMBL3263582)copy SMILEScopy InChI
Affinity DataIC50: 0.310nMAssay Description:In situ inhibition of ABHD6 in mouse Neuro2a cells after 4 hrs by gel-based competitive ABPP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FXRPubMed
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute

LigandPNGBDBM50010337(CHEMBL3263582)copy SMILEScopy InChI
Affinity DataIC50: 0.820nMAssay Description:Inhibition of ABHD6 in FP-rhodamine-labelled mouse brain membrane preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FXRPubMed
TargetMonoacylglycerol lipase ABHD6 [33-337](Homo sapiens (Human))TBA
LigandPNGBDBM645024(US20240010658, Example 5)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetMonoacylglycerol lipase ABHD6 [33-337](Homo sapiens (Human))TBA
LigandPNGBDBM645023(US20240010658, Example 3-10)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetMonoacylglycerol lipase ABHD6 [33-337](Homo sapiens (Human))TBA
LigandPNGBDBM645022(US20240010658, Example 3-9)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetMonoacylglycerol lipase ABHD6 [33-337](Homo sapiens (Human))TBA
LigandPNGBDBM645017(US20240010658, Example 2-1)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetMonoacylglycerol lipase ABHD6 [33-337](Homo sapiens (Human))TBA
LigandPNGBDBM645031(US20240010658, Example 15)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetMonoacylglycerol lipase ABHD6 [33-337](Homo sapiens (Human))TBA
LigandPNGBDBM645016(US20240010658, Example 2)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetMonoacylglycerol lipase ABHD6 [33-337](Homo sapiens (Human))TBA
LigandPNGBDBM645015(US20240010658, Example 1-4)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetMonoacylglycerol lipase ABHD6 [33-337](Homo sapiens (Human))TBA
LigandPNGBDBM645014(US20240010658, Example 1-2)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetMonoacylglycerol lipase ABHD6 [33-337](Homo sapiens (Human))TBA
LigandPNGBDBM645013(US20240010658, Example 1)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetMonoacylglycerol lipase ABHD6 [33-337](Homo sapiens (Human))TBA
LigandPNGBDBM645032(US20240010658, Example 16)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetMonoacylglycerol lipase ABHD6 [33-337](Homo sapiens (Human))TBA
LigandPNGBDBM645030(US20240010658, Example 12)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetMonoacylglycerol lipase ABHD6 [33-337](Homo sapiens (Human))TBA
LigandPNGBDBM645029(US20240010658, Example 10)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetMonoacylglycerol lipase ABHD6 [33-337](Homo sapiens (Human))TBA
LigandPNGBDBM645027(US20240010658, Example 8-1)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetMonoacylglycerol lipase ABHD6 [33-337](Homo sapiens (Human))TBA
LigandPNGBDBM645026(US20240010658, Example 6-2)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute

LigandPNGBDBM50010336(CHEMBL3263579)copy SMILEScopy InChI
Affinity DataIC50: 1.30nMAssay Description:Inhibition of ABHD6 in FP-rhodamine-labelled mouse brain membrane preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FXRPubMed
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute

LigandPNGBDBM50010335(CHEMBL3263577)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of ABHD6 in FP-rhodamine-labelled mouse brain membrane preincubated for 30 mins followed by FP-rhodamine labelling measured after 30 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FXRPubMed
TargetMonoacylglycerol lipase ABHD6 [33-337](Homo sapiens (Human))TBA
LigandPNGBDBM645025(US20240010658, Example 6)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Bristol-Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50608631(CHEMBL5274434)copy SMILES
Ligand Info
In DepthDetails
TargetMonoacylglycerol lipase ABHD6 [33-337](Homo sapiens (Human))TBA
LigandPNGBDBM645019(US20240010658, Example 2-14)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetMonoacylglycerol lipase ABHD6 [33-337](Homo sapiens (Human))TBA
LigandPNGBDBM645028(US20240010658, Example 9)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetMonoacylglycerol lipase ABHD6 [33-337](Homo sapiens (Human))TBA
LigandPNGBDBM645018(US20240010658, Example 2-6)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetMonoacylglycerol lipase ABHD6 [33-337](Homo sapiens (Human))TBA
LigandPNGBDBM645021(US20240010658, Example 3-6)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Bristol-Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50211266(CHEMBL3906477)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMMore data for this Ligand-Target Pair
In DepthDetails
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Bristol-Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50211266(CHEMBL3906477)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7C79PubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Bristol-Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50211257(CHEMBL3895863 | US10583137, Compound 14)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human ABHD6 using 2-AG as natural substrate by fluorescence based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7C79PubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Bristol-Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50608632(CHEMBL4279328)copy SMILES
Affinity DataIC50: 2.5nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Bristol-Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM50211257(CHEMBL3895863 | US10583137, Compound 14)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMMore data for this Ligand-Target Pair
In DepthDetails
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Bristol-Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM434879(US10583137, Compound 17 | tert-Butyl 3-benzyl-4-(4...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMMore data for this Ligand-Target Pair
In DepthDetails
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute

LigandPNGBDBM50010337(CHEMBL3263582)copy SMILEScopy InChI
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant mouse ABHD6 expressed in HEK293T using 2-arachidonoylglycerol preincubated for 30 mins followed by substrate addition measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1FXRPubMed
TargetMonoacylglycerol lipase ABHD6 [33-337](Homo sapiens (Human))TBA
LigandPNGBDBM645020(US20240010658, Example 3)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute

LigandPNGBDBM50052768(CHEMBL3318613)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of FP-rhodamine probe binding to ABHD6 in mouse brain membrane proteome preincubated for 1 hr followed by FP-rhodamine addition and measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9GCWPubMed
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute

LigandPNGBDBM50052781(CHEMBL3318603)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of FP-rhodamine probe binding to ABHD6 in mouse brain membrane proteome preincubated for 1 hr followed by FP-rhodamine addition and measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9GCWPubMed
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute

LigandPNGBDBM50052783(CHEMBL3318605)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of FP-rhodamine probe binding to ABHD6 in mouse brain membrane proteome preincubated for 1 hr followed by FP-rhodamine addition and measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9GCWPubMed
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute

LigandPNGBDBM50052767(CHEMBL3318612)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of FP-rhodamine probe binding to ABHD6 in mouse brain membrane proteome preincubated for 1 hr followed by FP-rhodamine addition and measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9GCWPubMed
TargetMonoacylglycerol lipase ABHD6(Mus musculus (mouse))
The Scripps Research Institute

LigandPNGBDBM50052782(CHEMBL3318604)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:Inhibition of FP-rhodamine probe binding to ABHD6 in mouse brain membrane proteome preincubated for 1 hr followed by FP-rhodamine addition and measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9GCWPubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Bristol-Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells at 1 uM pre-incubated for 10 mins before 2-AG substrate addition followed by rapid 40 fold compou...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP266BPubMed
TargetMonoacylglycerol lipase ABHD6(Homo sapiens (Human))
Bristol-Myers Squibb Co.

Curated by ChEMBL
LigandPNGBDBM24567((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)copy SMILEScopy InChI
Affinity DataIC50: 14nMAssay Description:Inhibition of human FAAH expressed in COS7 cell membranes pre-incubated for 10 mins before [3H]-AEA substrate addition by liquid scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP266BPubMed
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