Compile Data Set for Download or QSAR
Found 262 Enz. Inhib. hit(s) with Target = 'Aldehyde dehydrogenase, mitochondrial'
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50236899(CHEMBL4099822)copy SMILEScopy InChI
Affinity DataKi:  19nMAssay Description:Competitive inhibition of full length recombinant human ALDH2 expressed in Escherichia coli assessed as reduction in dehydrogenase activity using pro...More data for this Ligand-Target Pair
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50236900(CHEMBL4072941)copy SMILEScopy InChI
Affinity DataKi:  35nMAssay Description:In vitro for its ability to displace [3H]- spiperone from cloned human dopamine D2 short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32Z11PubMed
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50236900(CHEMBL4072941)copy SMILEScopy InChI
Affinity DataKi:  87nMAssay Description:Competitive inhibition of full length recombinant human ALDH2 expressed in Escherichia coli assessed as reduction in dehydrogenase activity using pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32Z11PubMed
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50236901(CHEMBL4061563)copy SMILEScopy InChI
Affinity DataKi:  310nMAssay Description:Displacement of [3H]spiperone from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32Z11PubMed
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50359990(PRUNETIN)copy SMILEScopy InChI
Affinity DataKi:  450nMAssay Description:Inhibition of human recombinant ALDH2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QF8TRFPubMed
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50448790(CHEMBL3128208)copy SMILEScopy InChI
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human ALDH2 using propionaldehyde as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50236904(CHEMBL1335126)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nMAssay Description:Competitive inhibition of full length recombinant human ALDH2 expressed in Escherichia coli assessed as reduction in dehydrogenase activity using pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32Z11PubMed
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50448790(CHEMBL3128208)copy SMILEScopy InChI
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition of human ALDH2 by Lineweaver-Burk plot analysis in presence of NAD+More data for this Ligand-Target Pair
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50236910(CHEMBL4083412)copy SMILEScopy InChI
Affinity DataKi:  2.40E+3nMAssay Description:Competitive inhibition of full length recombinant human ALDH2 expressed in Escherichia coli assessed as reduction in dehydrogenase activity using pro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32Z11PubMed
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50303403(2-(4-methyl-2-oxo-2H-chromen-7-yloxy)acetonitrile ...)copy SMILEScopy InChI
Affinity DataKi:  5.60E+3nMAssay Description:Mixed-type non-competitive inhibition of full length recombinant human ALDH2 expressed in Escherichia coli assessed as reduction in dehydrogenase act...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M32Z11PubMed
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM22794(1-benzyl-2,3-dihydro-1H-indole-2,3-dione | Isatin-...)copy SMILEScopy InChI
Affinity DataKi:  1.50E+4nMAssay Description:Competitive inhibition of human ALDH2 using propionaldehyde as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM22794(1-benzyl-2,3-dihydro-1H-indole-2,3-dione | Isatin-...)copy SMILEScopy InChI
Affinity DataKi:  3.40E+4nMAssay Description:Noncompetitive/mixed type inhibition of human ALDH2 by Lineweaver-Burk plot analysis in presence of NAD+More data for this Ligand-Target Pair
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM118233(US8673966, tert-butyl (1-(3-((3-(4-(methylsulfonam...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ28MXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50093535(11-(3-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yloxy)u...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of Hamster Liver mitochondrial ALDH-2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX49T8PubMed
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM118229(US8673966, N-(4-(7-((1-(cyclobutanecarbonyl)azetid...)copy SMILEScopy InChI
Affinity DataIC50: 4nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ28MXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50093537(10-(3-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yloxy)d...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of Hamster Liver mitochondrial ALDH-2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX49T8PubMed
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM118196(US8673966, N-(4-(7-((1-methyl-1H-imidazol-5-yl)eth...)copy SMILEScopy InChI
Affinity DataIC50: 4.90nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ28MXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM118228(US8673966, N-(4-(7-((1-(2,2-difluorocyclopropane- ...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ28MXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM118223(US8673966, N-(4-(7-((1-(3-hydroxy-3-methylcyclobut...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ28MXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM118232(US8673966, tert-butyl 1-(3-((3-(4- (methylsulfonam...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ28MXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM118209(US8673966, N-(4-(7-((1-(cyclopropanecarbonyl)azeti...)copy SMILEScopy InChI
Affinity DataIC50: 5nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ28MXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM118220(US8673966, N-(4-(7-((1-(3,3-difluorocyclobutanecar...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ28MXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM118230(US8673966, N-(4-(7-((1-(1-methylcyclopropanecarbon...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ28MXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM118225(US8673966, N-(4-(7-((1-(3-methyloxetane-3- carbony...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ28MXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM118231(US8673966, tert-butyl 1-(3-((3-(4-(methylsulfonami...)copy SMILEScopy InChI
Affinity DataIC50: 6nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ28MXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM118211(US8673966, N-(4-(7-((1-(cyclopropanecarbonyl)piper...)copy SMILEScopy InChI
Affinity DataIC50: 6.5nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ28MXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM118213(US8673966, N-(4-(7-((1-isopropyl-1H-imidazol-5- yl...)copy SMILEScopy InChI
Affinity DataIC50: 7nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ28MXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM118219(US8673966, N-(4-(7-((1-(3-methoxypropanoyl)azetidi...)copy SMILEScopy InChI
Affinity DataIC50: 8nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ28MXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM118216(US8673966, cyclopentyl 3-((3-(4- (methylsulfonamid...)copy SMILEScopy InChI
Affinity DataIC50: 9nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ28MXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM118208(US8673966, N-(4-(4-oxo-7-((2-oxo-1,2-dihydropyridi...)copy SMILEScopy InChI
Affinity DataIC50: 9nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ28MXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50093534(7-[3-(4-Hydroxy-phenyl)-4-oxo-4H-chromen-7-yloxy]-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of Hamster Liver mitochondrial ALDH-2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX49T8PubMed
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50093531(6-[3-(4-Hydroxy-phenyl)-4-oxo-4H-chromen-7-yloxy]-...)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of Hamster Liver mitochondrial ALDH-2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX49T8PubMed
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM118207(US8673966, tert-butyl 3-((3-(4-(methylsulfonamido)...)copy SMILEScopy InChI
Affinity DataIC50: 9nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ28MXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM118226(US8673966, N-(4-(7-((1-(2-hydroxypropanoyl)azetidi...)copy SMILEScopy InChI
Affinity DataIC50: 15nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ28MXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM118212(US8673966, N-(4-(7-((1,2-dimethyl-1H-imidazol-5- y...)copy SMILEScopy InChI
Affinity DataIC50: 15nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ28MXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM118222(US8673966, N-(4-(7-((1-(2-hydroxyacetyl)azetidin-3...)copy SMILEScopy InChI
Affinity DataIC50: 15nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ28MXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM118224(US8673966, N-(4-(7-((1-(2-hydroxy-2-methylpropanoy...)copy SMILEScopy InChI
Affinity DataIC50: 16nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ28MXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM118203(US8673966, N-(4-(4-oxo-7-(pyridin-3-ylethynyl)-4H-...)copy SMILEScopy InChI
Affinity DataIC50: 21nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ28MXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM153687(US10507215, Compound 4 | US9000015, 4)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3VRGUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM153690(US10507215, Compound 7 | US9000015, 7 | US9610299,...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9ZPVUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM153687(US10507215, Compound 4 | US9000015, 4)copy SMILEScopy InChI
Affinity DataIC50: 23nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4NNXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM153696(US10507215, Compound 13 | US9000015, 13 | US961029...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FQ9ZPVUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM153696(US10507215, Compound 13 | US9000015, 13 | US961029...)copy SMILEScopy InChI
Affinity DataIC50: 25nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q28S4NNXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM153696(US10507215, Compound 13 | US9000015, 13 | US961029...)copy SMILEScopy InChI
Affinity DataIC50: 25nMAssay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FF3VRGUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM118227(US8673966, N-(4-(7-((1-(1-methylpiperidine-4- carb...)copy SMILEScopy InChI
Affinity DataIC50: 35nMpH: 7.4Assay Description:Standard ALDH2 reaction mixtures contained 150 uM formaldehyde, 2.5 mM NAD+, 10 mM MgCl2 and 10 nM recombinant human ALDH2 in 50 mM Hepes buffer, pH ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QZ28MXUS Patent
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50104892(8-(3-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yloxy)oc...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of hamster liver aldehyde dehydrogenase ALDH-2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC0ZZZPubMed
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50104896(7-(2-(2-(2-hydroxyethoxy)ethoxy)ethoxy)-3-(4-hydro...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of hamster liver aldehyde dehydrogenase ALDH-2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC0ZZZPubMed
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50093535(11-(3-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yloxy)u...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of hamster liver aldehyde dehydrogenase ALDH-2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CC0ZZZPubMed
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50093538(3-(4-Hydroxyphenyl)-7-ethoxychromen-4-one | 7-Etho...)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of Hamster Liver mitochondrial ALDH-2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GX49T8PubMed
TargetAldehyde dehydrogenase, mitochondrial(Homo sapiens (Human))
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50409029(DAIDZIN)copy SMILEScopy InChI
Affinity DataIC50: 40nMAssay Description:Inhibition of Hamster Liver mitochondrial ALDH-2More data for this Ligand-Target Pair
Displayed 1 to 50 (of 262 total ) | Next | Last >>
Jump to: