Compile Data Set for Download or QSAR
Found 109 Enz. Inhib. hit(s) with Target = 'Alpha-glucosidase MAL12'
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM84968(Urea derivative, 12)copy SMILEScopy InChI
Affinity DataKi:  3.20E+3nM IC50: 8.40E+3nMAssay Description:All enzymatic activities were determined by using the appropriate substrate (p-nitrophenyl-alpha-D-glucopyranoside, p-nitrophenyl-beta-D-gulcopyranos...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542M33PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM84969(Urea derivative, 13)copy SMILEScopy InChI
Affinity DataKi:  4.60E+3nM IC50: 1.43E+4nMAssay Description:All enzymatic activities were determined by using the appropriate substrate (p-nitrophenyl-alpha-D-glucopyranoside, p-nitrophenyl-beta-D-gulcopyranos...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542M33PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM84967(Urea derivative, 11)copy SMILEScopy InChI
Affinity DataKi:  7.20E+3nM IC50: 1.98E+4nMAssay Description:All enzymatic activities were determined by using the appropriate substrate (p-nitrophenyl-alpha-D-glucopyranoside, p-nitrophenyl-beta-D-gulcopyranos...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542M33PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM84972(Urea derivative, 16)copy SMILEScopy InChI
Affinity DataKi:  9.40E+3nM IC50: 1.85E+4nMAssay Description:All enzymatic activities were determined by using the appropriate substrate (p-nitrophenyl-alpha-D-glucopyranoside, p-nitrophenyl-beta-D-gulcopyranos...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542M33PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM84963(Urea derivative, 7)copy SMILEScopy InChI
Affinity DataKi:  1.05E+4nM IC50: 1.95E+4nMAssay Description:All enzymatic activities were determined by using the appropriate substrate (p-nitrophenyl-alpha-D-glucopyranoside, p-nitrophenyl-beta-D-gulcopyranos...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542M33PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM84962(Urea derivative, 6)copy SMILEScopy InChI
Affinity DataKi:  1.06E+4nM IC50: 4.21E+4nMAssay Description:All enzymatic activities were determined by using the appropriate substrate (p-nitrophenyl-alpha-D-glucopyranoside, p-nitrophenyl-beta-D-gulcopyranos...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542M33PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM84966(Urea derivative, 10)copy SMILEScopy InChI
Affinity DataKi:  1.21E+4nM IC50: 2.88E+4nMAssay Description:All enzymatic activities were determined by using the appropriate substrate (p-nitrophenyl-alpha-D-glucopyranoside, p-nitrophenyl-beta-D-gulcopyranos...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542M33PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM243075(α-Gl inhibitor, C3)copy SMILES
Affinity DataKi:  1.40E+4nMpH: 7.0Assay Description:In this study, the inhibition assay of yeast enzyme was performed in 100 mM phosphate buffer pH 7.0 at 25蚓 with minor changes, according to the meth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP73V0PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM84970(Urea derivative, 14)copy SMILEScopy InChI
Affinity DataKi:  1.70E+4nM IC50: 2.91E+4nMAssay Description:All enzymatic activities were determined by using the appropriate substrate (p-nitrophenyl-alpha-D-glucopyranoside, p-nitrophenyl-beta-D-gulcopyranos...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542M33PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM18351((2R,3R,4R,5S)-2-(Hydroxymethyl)piperidine-3,4,5-tr...)copy SMILEScopy InChI
Affinity DataKi:  1.80E+4nM IC50: 3.95E+4nMAssay Description:All enzymatic activities were determined by using the appropriate substrate (p-nitrophenyl-alpha-D-glucopyranoside, p-nitrophenyl-beta-D-gulcopyranos...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542M33PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)copy SMILEScopy InChI
Affinity DataKi:  2.15E+4nM IC50: 2.64E+4nMAssay Description:All enzymatic activities were determined by using the appropriate substrate (p-nitrophenyl-alpha-D-glucopyranoside, p-nitrophenyl-beta-D-gulcopyranos...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542M33PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM243074(α-Gl inhibitor, C2)copy SMILES
Affinity DataKi:  3.00E+4nMpH: 7.0Assay Description:In this study, the inhibition assay of yeast enzyme was performed in 100 mM phosphate buffer pH 7.0 at 25蚓 with minor changes, according to the meth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP73V0PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM84959(Stilbene derivative, 2)copy SMILEScopy InChI
Affinity DataKi:  3.51E+4nM IC50: 4.64E+4nMAssay Description:All enzymatic activities were determined by using the appropriate substrate (p-nitrophenyl-alpha-D-glucopyranoside, p-nitrophenyl-beta-D-gulcopyranos...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2542M33PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM243073(α-Gl inhibitor, C1)copy SMILES
Affinity DataKi:  7.00E+4nMpH: 7.0Assay Description:In this study, the inhibition assay of yeast enzyme was performed in 100 mM phosphate buffer pH 7.0 at 25蚓 with minor changes, according to the meth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP73V0PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM243074(α-Gl inhibitor, C2)copy SMILES
Affinity DataKi:  1.30E+5nMpH: 7.0Assay Description:In this study, the inhibition assay of yeast enzyme was performed in 100 mM phosphate buffer pH 7.0 at 25蚓 with minor changes, according to the meth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP73V0PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM243073(α-Gl inhibitor, C1)copy SMILES
Affinity DataKi:  1.70E+5nMpH: 7.0Assay Description:In this study, the inhibition assay of yeast enzyme was performed in 100 mM phosphate buffer pH 7.0 at 25蚓 with minor changes, according to the meth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP73V0PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM152497((E)-N'-(6-Bromo-2-oxoindolin-3-ylidene)-2-(2,4...)copy SMILEScopy InChI
Affinity DataIC50: 2.20E+3nMAssay Description:10 無 of test samples (5 mg/mL DMSO solution) were reconstituted in 100 無 of 100 mM-phosphate buffer (pH6.8) in 96-well microplate and incubated wit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2T7RPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM152499((E)-N'-(2-oxoindolin-3-ylidene)dodecanehydrazi...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:10 無 of test samples (5 mg/mL DMSO solution) were reconstituted in 100 無 of 100 mM-phosphate buffer (pH6.8) in 96-well microplate and incubated wit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2T7RPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM152496((E)-N'-(6-bromo-2-oxoindolin-3-ylidene)-2-(3,4...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:10 無 of test samples (5 mg/mL DMSO solution) were reconstituted in 100 無 of 100 mM-phosphate buffer (pH6.8) in 96-well microplate and incubated wit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2T7RPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM50308256(1-O-Methyl-2,3-O-isopropylidene-5-(4-cyclohexene-1...)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of yeast alpha-glucosidase MAL12 assessed as inhibition of p-nitrophenol release by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9QC7PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM50308259(1-O-Methyl-2,3-O-isopropylidene-5-[4-(1-hydroxycyc...)copy SMILEScopy InChI
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of yeast alpha-glucosidase MAL12 assessed as inhibition of p-nitrophenol release by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9QC7PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM50308258(1-O-Methyl-2,3-O-isopropylidene-5-(4-phenoxymethyl...)copy SMILEScopy InChI
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of yeast alpha-glucosidase MAL12 assessed as inhibition of p-nitrophenol release by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9QC7PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM181062((E)-N'-(3,5-Dichloro-2-hydroxybenzylidene)-4-(...)copy SMILEScopy InChI
Affinity DataIC50: 6.24E+3nMpH: 6.8Assay Description:The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed by u...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445K8RPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM181064((E)-N'-(5-Chloro-2-hydroxybenzylidene)-4-(2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 8.23E+3nMpH: 6.8Assay Description:The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed by u...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445K8RPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM243075(α-Gl inhibitor, C3)copy SMILES
Affinity DataIC50: 9.60E+3nMpH: 7.0Assay Description:In this study, the inhibition assay of yeast enzyme was performed in 100 mM phosphate buffer pH 7.0 at 25蚓 with minor changes, according to the meth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP73V0PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM181061((E)-N'-(3,5-Di-tert-butyl-2-hydroxybenzylidene...)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+4nMpH: 6.8Assay Description:The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed by u...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445K8RPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM181068((E)-N'-(4-Chlorobenzylidene)-4-(2-oxo-2H-chrom...)copy SMILEScopy InChI
Affinity DataIC50: 1.06E+4nMpH: 6.8Assay Description:The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed by u...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445K8RPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM152498((E)-N'-(6-bromo-2-oxoindolin-3-ylidene)-2- hyd...)copy SMILEScopy InChI
Affinity DataIC50: 1.18E+4nMAssay Description:10 無 of test samples (5 mg/mL DMSO solution) were reconstituted in 100 無 of 100 mM-phosphate buffer (pH6.8) in 96-well microplate and incubated wit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2T7RPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM181069((E)-N'-(3-Chlorobenzylidene)-4-(2-oxo-2H-chrom...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMpH: 6.8Assay Description:The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed by u...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445K8RPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM181073((E)-N'-(3-bromobenzylidene)-4-(2-oxo-2H-chrome...)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMpH: 6.8Assay Description:The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed by u...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445K8RPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM50308255(1-O-Methyl-2,3-O-isopropylidene-5-(4-phenyl-1H-1,2...)copy SMILEScopy InChI
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of yeast alpha-glucosidase MAL12 assessed as inhibition of p-nitrophenol release by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9QC7PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM50308257(1-O-Methyl-2,3-O-isopropylidene-5-(4-carboxylate e...)copy SMILEScopy InChI
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of yeast alpha-glucosidase MAL12 assessed as inhibition of p-nitrophenol release by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9QC7PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM181070((E)-4-(2-Oxo-2H-chromen-3-yl)-N'-(4-(trifluoro...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+4nMpH: 6.8Assay Description:The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed by u...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445K8RPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM181063((E)-N'-(3-Fluoro-4-hydroxybenzylidene)-4-(2-ox...)copy SMILEScopy InChI
Affinity DataIC50: 1.66E+4nMpH: 6.8Assay Description:The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed by u...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445K8RPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM181067((E)-N'-(3,4-Dihydroxybenzylidene)-4-(2-oxo-2H-...)copy SMILEScopy InChI
Affinity DataIC50: 1.83E+4nMpH: 6.8Assay Description:The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed by u...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445K8RPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM152494((E)-2-(2,4-dichlorophenyl)-N'-(2-oxo-1-propyli...)copy SMILEScopy InChI
Affinity DataIC50: 1.83E+4nMAssay Description:10 無 of test samples (5 mg/mL DMSO solution) were reconstituted in 100 無 of 100 mM-phosphate buffer (pH6.8) in 96-well microplate and incubated wit...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2T7RPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM60591((E)-N'-(3-Fluorobenzylidene)-4-(2-oxo-2H-chromen-3...)copy SMILEScopy InChI
Affinity DataIC50: 2.26E+4nMpH: 6.8Assay Description:The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed by u...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445K8RPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM181071((E)-N'-(2-Fluorobenzylidene)-4-(2-oxo-2H-chrom...)copy SMILEScopy InChI
Affinity DataIC50: 2.36E+4nMpH: 6.8Assay Description:The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed by u...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445K8RPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM243068(11-O-(3',4'-dimethoxybenzoyl)-bergenin (6))copy SMILEScopy InChI
Affinity DataIC50: 2.46E+4nMpH: 7.0 T: 2°CAssay Description:α-glucosidase (25 μL, 0.2 U/mL), 25 μL of various concentrations of samples, and 175 μL of 50 mM sodium phosphate buffer (pH 7.0)...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7MCRPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM50308260(1-O-Methyl-2,3-O-isopropylidene-5-[4-(tetrahydro-2...)copy SMILEScopy InChI
Affinity DataIC50: 2.47E+4nMAssay Description:Inhibition of yeast alpha-glucosidase MAL12 assessed as inhibition of p-nitrophenol release by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9QC7PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM243074(α-Gl inhibitor, C2)copy SMILES
Affinity DataIC50: 2.51E+4nMpH: 7.0Assay Description:In this study, the inhibition assay of yeast enzyme was performed in 100 mM phosphate buffer pH 7.0 at 25蚓 with minor changes, according to the meth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XP73V0PubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM181060((E)-N'-(4-Hydroxybenzylidene)-4-(2-oxo-2H-chro...)copy SMILEScopy InChI
Affinity DataIC50: 2.52E+4nMpH: 6.8Assay Description:The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed by u...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445K8RPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM181065((E)-N'-(2-Hydroxy-4-methoxybenzylidene)-4-(2-o...)copy SMILEScopy InChI
Affinity DataIC50: 2.99E+4nMpH: 6.8Assay Description:The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed by u...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445K8RPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM50180587(CHEMBL3734896)copy SMILEScopy InChI
Affinity DataIC50: 3.39E+4nMAssay Description:Inhibition of yeast alpha-glucosidase MAL12 using 4-nitrophenyl-alpha-D-glucopyranoside as substrate preincubated for 30 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B910HPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM50207546((-)-epivaliolamine | CHEMBL223096)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of baker's yeast alpha-glucosidaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4PKFPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM181059((E)-N'-(2-Hydroxybenzylidene)-4-(2-oxo-2H-chro...)copy SMILEScopy InChI
Affinity DataIC50: 3.72E+4nMpH: 6.8Assay Description:The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed by u...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445K8RPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM50333465((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...)copy SMILEScopy InChI
Affinity DataIC50: 3.83E+4nMpH: 6.8 T: 2°CAssay Description:Reaction mixture (100 µL) contained 70 µL 50 mM Na2HPO4 buffer, pH 6.8, 10 µL test compound (0.5 mM), followed by the addition of 10 &...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NG4P8QPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM181066((E)-N'-(2,4-Dihydroxybenzylidene)-4-(2-oxo-2H-...)copy SMILEScopy InChI
Affinity DataIC50: 3.86E+4nMpH: 6.8Assay Description:The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed by u...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445K8RPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM23406((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)copy SMILEScopy InChI
Affinity DataIC50: 4.33E+4nMpH: 6.8Assay Description:The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed by u...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2445K8RPubMed
TargetAlpha-glucosidase MAL12(Saccharomyces cerevisiae)
Gyeongsang National University

LigandPNGBDBM50190320(CHEMBL3827545)copy SMILEScopy InChI
Affinity DataIC50: 4.98E+4nMAssay Description:Inhibition of yeast alpha-glucosidase MAL12 using 4-nitrophenyl-alpha-D-glucopyranoside as substrate preincubated for 30 mins followed by substrate a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22B910HPubMed
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