Compile Data Set for Download or QSAR
Found 73 Enz. Inhib. hit(s) with Target = 'Acid-sensing ion channel 3'
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348097(CHEMBL1800440)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Inhibition of ASIC3 assessed as inhibition of peak current by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08P8PubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348098(CHEMBL1800430)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Inhibition of ASIC3 assessed as inhibition of peak current by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08P8PubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348111(CHEMBL1800436)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of ASIC3 assessed as inhibition of peak current by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08P8PubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348107(CHEMBL1800432)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of ASIC3 assessed as inhibition of peak current by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08P8PubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348104(CHEMBL1800428)copy SMILEScopy InChI
Affinity DataIC50: 270nMAssay Description:Inhibition of ASIC3 assessed as inhibition of peak current by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08P8PubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348113(CHEMBL1800433)copy SMILEScopy InChI
Affinity DataIC50: 310nMAssay Description:Inhibition of ASIC3 assessed as inhibition of peak current by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08P8PubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348099(CHEMBL1800331)copy SMILEScopy InChI
Affinity DataIC50: 460nMAssay Description:Inhibition of ASIC3 assessed as inhibition of peak current by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08P8PubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50259583(3-amino-5-(biphenyl-3-yl)-N-(diaminomethylene)pyra...)copy SMILEScopy InChI
Affinity DataIC50: 490nMAssay Description:Inhibition of ASIC3 (unknown origin) assessed as inhibition of peak current by patch clamp electrophisiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6CS6PubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348095(CHEMBL1800437)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of ASIC3 assessed as inhibition of peak current by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08P8PubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50259353(3-amino-6-chloro-N-(diaminomethylene)-5-(naphthale...)copy SMILEScopy InChI
Affinity DataIC50: 510nMAssay Description:Inhibition of ASIC3 (unknown origin) assessed as inhibition of peak current by patch clamp electrophisiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6CS6PubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50259584(3-amino-N-(diaminomethylene)-5-(3-(thiophen-3-yl)p...)copy SMILEScopy InChI
Affinity DataIC50: 640nMAssay Description:Inhibition of ASIC3 (unknown origin) assessed as inhibition of peak current by patch clamp electrophisiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6CS6PubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348106(CHEMBL1800431)copy SMILEScopy InChI
Affinity DataIC50: 680nMAssay Description:Inhibition of ASIC3 assessed as inhibition of peak current by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08P8PubMed
TargetAcid-sensing ion channel 3(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50259583(3-amino-5-(biphenyl-3-yl)-N-(diaminomethylene)pyra...)copy SMILEScopy InChI
Affinity DataIC50: 950nMAssay Description:Inhibition of rat ASIC3 assessed as inhibition of peak current by patch clamp electrophisiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6CS6PubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342661(2-(3-(phenylethynyl)phenyl)pyridin-4-amine | CHEMB...)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3MVJPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342642(6-(6-(2-methylpiperidin-1-yl)pyridin-2-yl)-1,2,3,4...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3MVJPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348112(CHEMBL1800438)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of ASIC3 assessed as inhibition of peak current by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08P8PubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342660(4-(3-(4-aminopyridin-2-yl)phenyl)but-3-yn-1-ol | C...)copy SMILEScopy InChI
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3MVJPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348103(CHEMBL1800427)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of ASIC3 assessed as inhibition of peak current by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08P8PubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342647(6-(4-(4-methylpiperazin-1-yl)-3-(trifluoromethyl)p...)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3MVJPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342641(6-(3,5-dichlorophenyl)-1,2,3,4-tetrahydroisoquinol...)copy SMILEScopy InChI
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3MVJPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348102(CHEMBL1800334)copy SMILEScopy InChI
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of ASIC3 assessed as inhibition of peak current by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08P8PubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342649(6-methyl-N-(4-(6-(piperazin-1-yl)pyridin-3-yl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3MVJPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348096(CHEMBL1800439)copy SMILEScopy InChI
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of ASIC3 assessed as inhibition of peak current by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08P8PubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM16173(3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...)copy SMILEScopy InChI
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of ASIC3 (unknown origin) assessed as inhibition of peak current by patch clamp electrophisiologyMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6CS6PubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348101(CHEMBL1800333)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of ASIC3 assessed as inhibition of peak current by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08P8PubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342662(2-phenyl-6-(pyridin-2-ylmethyl)pyridin-4-amine | C...)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3MVJPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348100(CHEMBL1800332)copy SMILEScopy InChI
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of ASIC3 assessed as inhibition of peak current by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08P8PubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342659(2-phenylpyridin-4-amine | CHEMBL1770738)copy SMILEScopy InChI
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3MVJPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342643(6-(3-(trifluoromethyl)phenyl)-1,2,3,4-tetrahydrois...)copy SMILEScopy InChI
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3MVJPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342651(CHEMBL1770730 | N-(6-methylpyridin-2-yl)furo[2,3-c...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3MVJPubMed
TargetAcid-sensing ion channel 3(Rattus norvegicus)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157090(6-(2-(1-isopropyl-2-methyl-1,2,3,4-tetrahydroisoqu...)copy SMILEScopy InChI
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of ASIC3 in rat DRG neuronsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61GZPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342650(4-amino-N-(4-chlorophenethyl)-2-propylquinoline-6-...)copy SMILEScopy InChI
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3MVJPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348108(CHEMBL1800434)copy SMILEScopy InChI
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of ASIC3 assessed as inhibition of peak current by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08P8PubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342640(6-bromo-2-((5-methoxy-1H-indol-3-yl)methyl)-1,2,3,...)copy SMILEScopy InChI
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3MVJPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342646(6-(4-(4-methylpiperazin-1-yl)phenyl)-1,2,3,4-tetra...)copy SMILEScopy InChI
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3MVJPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342648(2-methyl-4-(4-(6-methylpyridin-2-ylamino)phenyl)bu...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3MVJPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348110(CHEMBL1800079)copy SMILEScopy InChI
Affinity DataIC50: 1.71E+4nMAssay Description:Inhibition of ASIC3 assessed as inhibition of peak current by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08P8PubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342645(6-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-5-yl)-1,2,...)copy SMILEScopy InChI
Affinity DataIC50: 1.94E+4nMAssay Description:Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3MVJPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342663(4-(6-bromo-3,4-dihydroisoquinolin-2(1H)-yl)-2-meth...)copy SMILEScopy InChI
Affinity DataIC50: 2.76E+4nMAssay Description:Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3MVJPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348109(CHEMBL1800435)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ASIC3 assessed as inhibition of peak current by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08P8PubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50348105(CHEMBL1800429)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of ASIC3 assessed as inhibition of peak current by electrophysiology methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DZ08P8PubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50296576(2-(3-chloro-5-methylphenyl)-1H-indole-5-carboximid...)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of ASIC3 by patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1Z8KPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50296570(2-(3-bromo-5-fluorophenyl)-1H-indole-5-carboximida...)copy SMILEScopy InChI
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of ASIC3 by patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1Z8KPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50296571(2-(3,5-dibromophenyl)-1H-indole-5-carboximidamide ...)copy SMILEScopy InChI
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of ASIC3 by patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1Z8KPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50296575(2-(3-(benzylamino)-5-chlorophenyl)-1H-indole-5-car...)copy SMILEScopy InChI
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibition of ASIC3 by patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1Z8KPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50296573(2-(3-amino-5-chlorophenyl)-1H-indole-5-carboximida...)copy SMILEScopy InChI
Affinity DataIC50: 9.50E+4nMAssay Description:Inhibition of ASIC3 by patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1Z8KPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342656(CHEMBL1770735 | benzo[b]thiophen-2-ylmethanamine)copy SMILEScopy InChI
Affinity DataIC50: 9.70E+4nMAssay Description:Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3MVJPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342644(2-((5-methoxy-1H-indol-3-yl)methyl)-6-(3-(trifluor...)copy SMILEScopy InChI
Affinity DataIC50: 1.03E+5nMAssay Description:Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3MVJPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50296574(2-(3-chloro-5-((phenylamino)methyl)phenyl)-1H-indo...)copy SMILEScopy InChI
Affinity DataIC50: 1.14E+5nMAssay Description:Inhibition of ASIC3 by patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR1Z8KPubMed
TargetAcid-sensing ion channel 3(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50342654(6-phenylpyrimidin-4-amine | CHEMBL1770733)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of human ASIC3 expressed in HEK293 cells assessed as inhibition of acid-evoked current by manual patch-clamp electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QV3MVJPubMed
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