Compile Data Set for Download or QSAR
Found 32 Enz. Inhib. hit(s) with Target = 'Amyloid beta-binding alcohol dehydrogenase'
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232928(US9346839, 9 | US9738668, Compound 9)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232926(US9346839, 7 | US9738668, Compound 7)copy SMILEScopy InChI
Affinity DataKi:  2.80E+3nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232923(US9346839, 4 | US9738668, Compound 4)copy SMILEScopy InChI
Affinity DataKi:  5.50E+3nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232930(US9346839, 11 | US9738668, Compound 11)copy SMILES
Affinity DataKi:  9.60E+3nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232927(US9346839, 8 | US9738668, Compound 8)copy SMILEScopy InChI
Affinity DataKi:  1.49E+4nMAssay Description:To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232929(US9346839, 10 | US9738668, Compound 10)copy SMILEScopy InChI
Affinity DataKi:  3.40E+4nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232925(US9346839, 6 | US9738668, Compound 6)copy SMILEScopy InChI
Affinity DataKi:  4.49E+4nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232927(US9346839, 8 | US9738668, Compound 8)copy SMILEScopy InChI
Affinity DataKi:  7.06E+4nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232924(US9346839, 5 | US9738668, Compound 5)copy SMILEScopy InChI
Affinity DataKi:  9.11E+4nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232923(US9346839, 4 | US9738668, Compound 4)copy SMILEScopy InChI
Affinity DataKi:  9.66E+4nMAssay Description:To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232931(US9346839, 15 | US9738668, Compound 15)copy SMILEScopy InChI
Affinity DataKi:  3.56E+5nMAssay Description:To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM50450824(CHEMBL4203009)copy SMILEScopy InChI
Affinity DataIC50: 69nMAssay Description:Inhibition of ABAD (unknown origin) assessed as residual activity using acetoacetyl-CoA in presence of NADH by spectrophotometric assay relative to c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7DPVPubMed
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM50450824(CHEMBL4203009)copy SMILEScopy InChI
Affinity DataIC50: 92nMAssay Description:Inhibition of ABAD (unknown origin) by cell based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7DPVPubMed
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232928(US9346839, 9 | US9738668, Compound 9)copy SMILEScopy InChI
Affinity DataIC50: 7.20E+3nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232926(US9346839, 7 | US9738668, Compound 7)copy SMILEScopy InChI
Affinity DataIC50: 9.90E+3nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232923(US9346839, 4 | US9738668, Compound 4)copy SMILEScopy InChI
Affinity DataIC50: 1.96E+4nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232930(US9346839, 11 | US9738668, Compound 11)copy SMILES
Affinity DataIC50: 3.41E+4nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232927(US9346839, 8 | US9738668, Compound 8)copy SMILEScopy InChI
Affinity DataIC50: 5.27E+4nMAssay Description:To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232929(US9346839, 10 | US9738668, Compound 10)copy SMILEScopy InChI
Affinity DataIC50: 1.25E+5nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232925(US9346839, 6 | US9738668, Compound 6)copy SMILEScopy InChI
Affinity DataIC50: 1.65E+5nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232927(US9346839, 8 | US9738668, Compound 8)copy SMILEScopy InChI
Affinity DataIC50: 2.59E+5nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232924(US9346839, 5 | US9738668, Compound 5)copy SMILEScopy InChI
Affinity DataIC50: 3.35E+5nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232923(US9346839, 4 | US9738668, Compound 4)copy SMILEScopy InChI
Affinity DataIC50: 3.41E+5nMAssay Description:To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232931(US9346839, 15 | US9738668, Compound 15)copy SMILEScopy InChI
Affinity DataIC50: 1.26E+6nMAssay Description:To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232931(US9346839, 15 | US9738668, Compound 15)copy SMILEScopy InChI
Affinity DataKd:  264nMAssay Description:To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232923(US9346839, 4 | US9738668, Compound 4)copy SMILEScopy InChI
Affinity DataKd:  496nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232927(US9346839, 8 | US9738668, Compound 8)copy SMILEScopy InChI
Affinity DataKd:  291nMAssay Description:To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232923(US9346839, 4 | US9738668, Compound 4)copy SMILEScopy InChI
Affinity DataKd:  496nMAssay Description:To perform kinetic analyses of the binding of phosphonate derivatives to ABAD, the BIACORE 3000 instrument (based on surface plasmon resonance [SPR] ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232924(US9346839, 5 | US9738668, Compound 5)copy SMILEScopy InChI
Affinity DataKd:  954nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232930(US9346839, 11 | US9738668, Compound 11)copy SMILES
Affinity DataKd:  380nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232928(US9346839, 9 | US9738668, Compound 9)copy SMILEScopy InChI
Affinity DataKd:  264nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent
TargetAmyloid beta-binding alcohol dehydrogenase(Homo sapiens (Human))
University of Kansas

US Patent
LigandPNGBDBM232926(US9346839, 7 | US9738668, Compound 7)copy SMILEScopy InChI
Affinity DataKd:  256nMAssay Description:The assay for the inhibition of reduction of S-acetoacetyl-CoA (SAAC) by ABAD was carried out with ABAD (418 ng/ml), SAAC (172 μM), NADH (102 &#...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22Z17NPUS Patent