Found 39 Enz. Inhib. hit(s) with Target = '7-dehydrocholesterol reductase' Target7-dehydrocholesterol reductase(Rattus norvegicus)
Smith Kline Beecham Pharmaceuticals
Curated by ChEMBL
Smith Kline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Compound was tested for the inhibition of Delta-(24)-sterol reductaseMore data for this Ligand-Target Pair
Target7-dehydrocholesterol reductase(Rattus norvegicus)
Smith Kline Beecham Pharmaceuticals
Curated by ChEMBL
Smith Kline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 7nMAssay Description:Compound was tested for the inhibition of Delta-(24)-sterol reductaseMore data for this Ligand-Target Pair
Target7-dehydrocholesterol reductase(Rattus norvegicus)
Smith Kline Beecham Pharmaceuticals
Curated by ChEMBL
Smith Kline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 12nMAssay Description:Compound was tested for the inhibition of delta24-sterol reductaseMore data for this Ligand-Target Pair
Target7-dehydrocholesterol reductase(Rattus norvegicus)
Smith Kline Beecham Pharmaceuticals
Curated by ChEMBL
Smith Kline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 33nMAssay Description:Compound was tested for the inhibition of delta24-sterol reductaseMore data for this Ligand-Target Pair
Target7-dehydrocholesterol reductase(Rattus norvegicus)
Smith Kline Beecham Pharmaceuticals
Curated by ChEMBL
Smith Kline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 48nMAssay Description:Compound was tested for the inhibition of delta24-sterol reductaseMore data for this Ligand-Target Pair
Target7-dehydrocholesterol reductase(Rattus norvegicus)
Smith Kline Beecham Pharmaceuticals
Curated by ChEMBL
Smith Kline Beecham Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 2.00E+3nMAssay Description:Compound was tested for the inhibition of Delta-(24)-sterol reductaseMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Antagonistic activity for carbachol induced contractions in guinea pig ileum against Muscarinic acetylcholine receptor M3 in the presence of mepyrami...More data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 2.30nMAssay Description:Inhibition of 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate after 2...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Tetsed for Antagonistic activity at histamine H3 receptor in guinea pig ileal longitudinal muscle in the presence of mepyramine at a concentration of...More data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 30nMAssay Description:Growth inhibition of MCF7 cells expressing ER and antiestrogen binding sitesMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Growth inhibition of MDA-MB-231 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Growth inhibition of MDA-MB-435 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Growth inhibition of MDA-MB-435 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Growth inhibition of multidrug resistant MCF7/Adr cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Growth inhibition of MCF7 cells expressing ER and antiestrogen binding sitesMore data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Growth inhibition of MDA-MB-231 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate after 2...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Growth inhibition of MDA-MB-435 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Growth inhibition of MCF7 cells expressing ER and antiestrogen binding sitesMore data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Growth inhibition of MDA-MB-231 cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
Affinity DataIC50: 400nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate after 2...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.07E+3nMAssay Description:Histamine-induced inhibition of forskolin- stimulated cAMP accumulation in SK-N-MC cells overexpressing the human Histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 1.39E+3nMAssay Description:Histamine-induced inhibition of forskolin- stimulated cAMP accumulation in SK-N-MC cells overexpressing the human Histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 2.00E+3nMAssay Description:Growth inhibition of multidrug resistant MCF7/Adr cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.04E+3nMAssay Description:Histamine-induced inhibition of forskolin- stimulated cAMP accumulation in SK-N-MC cells overexpressing the human Histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 2.80E+3nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 3.50E+3nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 6.80E+3nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of 7-dehydroxycholesterol reductase-mediated cholesterol biosynthesis in human HL60 cells assessed as inhibition of 2-[13C]acetate after 2...More data for this Ligand-Target Pair
Affinity DataIC50: 7.40E+3nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 8.00E+3nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Growth inhibition of multidrug resistant MCF7/Adr cells containing antiestrogen binding sitesMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+4nMAssay Description:Displacement of [3H]tamoxifen from antiestrogen binding site in Sprague-Dawley rat liver by liquid scintillation countingMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Histamine-induced inhibition of forskolin- stimulated cAMP accumulation in SK-N-MC cells overexpressing the human Histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataIC50: 5.00E+4nMAssay Description:Histamine-induced inhibition of forskolin- stimulated cAMP accumulation in SK-N-MC cells overexpressing the human Histamine H3 receptorMore data for this Ligand-Target Pair
In DepthDetails
Affinity DataKd: 1nMAssay Description:Binding affinity towards antiestrogen binding site AEBSMore data for this Ligand-Target Pair
