Compile Data Set for Download or QSAR
Found 17 Enz. Inhib. hit(s) with Target = 'Aquaporin-1'
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM50166561(CHEMBL195380 | Naphthalene-1-sulfonic acid {4-[(4-...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM50089038(CGP 71683 | CGP-71683A | CHEMBL17645 | N-{[(1r,4r)...)copy SMILEScopy InChI
Affinity DataIC50: 2.70E+3nMAssay Description:Osmotic water permeability was measured at 22-24 °C bymonitoring 90° scattered light intensity at 520 nm wavelength. Measurements were made using a P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6WHZPubMed
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM50354083(CHEMBL1836102 | N-{[(1r,4r)-4-{[(4-aminoquinazolin...)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Osmotic water permeability was measured at 22-24 °C bymonitoring 90° scattered light intensity at 520 nm wavelength. Measurements were made using a P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6WHZPubMed
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM178091(5-chloro-N-{[(1r,4r)-4-{[(4-aminoquinazolin-2-yl)a...)copy SMILEScopy InChI
Affinity DataIC50: 5.80E+3nMAssay Description:Osmotic water permeability was measured at 22-24 °C bymonitoring 90° scattered light intensity at 520 nm wavelength. Measurements were made using a P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6WHZPubMed
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM50607942(CHEMBL5280011)copy SMILES
Affinity DataIC50: 5.80E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM178092({[7-(2,4-dichlorophenyl)-5-fluoro-2,3-dihydro-1-be...)copy SMILEScopy InChI
Affinity DataIC50: 9.80E+3nMAssay Description:Osmotic water permeability was measured at 22-24 °C bymonitoring 90° scattered light intensity at 520 nm wavelength. Measurements were made using a P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6WHZPubMed
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM178092({[7-(2,4-dichlorophenyl)-5-fluoro-2,3-dihydro-1-be...)copy SMILEScopy InChI
Affinity DataIC50: 9.80E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM178093([7-(2,4-dichlorophenyl)-5-fluoro-2,3-dihydro-1-ben...)copy SMILEScopy InChI
Affinity DataIC50: 1.52E+4nMMore data for this Ligand-Target Pair
In DepthDetails
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM178093([7-(2,4-dichlorophenyl)-5-fluoro-2,3-dihydro-1-ben...)copy SMILEScopy InChI
Affinity DataIC50: 1.52E+4nMAssay Description:Osmotic water permeability was measured at 22-24 °C bymonitoring 90° scattered light intensity at 520 nm wavelength. Measurements were made using a P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6WHZPubMed
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM50607939(CHEMBL1537920)copy SMILES
Affinity DataIC50: 1.75E+4nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM50607938(CHEMBL5280895)copy SMILES
Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM178094({[7-(2,6-dichlorophenyl)-5-fluoro-2,3-dihydro-1-be...)copy SMILEScopy InChI
Affinity DataIC50: 2.94E+4nMAssay Description:Osmotic water permeability was measured at 22-24 °C bymonitoring 90° scattered light intensity at 520 nm wavelength. Measurements were made using a P...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ6WHZPubMed
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM178094({[7-(2,6-dichlorophenyl)-5-fluoro-2,3-dihydro-1-be...)copy SMILEScopy InChI
Affinity DataIC50: 2.94E+4nMMore data for this Ligand-Target Pair
In DepthDetails
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM50607940(CHEMBL5282904)copy SMILES
Affinity DataIC50: 1.70E+7nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM50607943(CHEMBL1740905)copy SMILES
Affinity DataEC50:  2.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM94509((E)-2-butenedioic acid;2-[4-tert-butyl-1-[(4-fluor...)copy SMILEScopy InChI
Affinity DataEC50:  4.80E+4nMMore data for this Ligand-Target Pair
In DepthDetails
TargetAquaporin-1(Homo sapiens (Human))TBA
LigandPNGBDBM50607941(CHEMBL5268096)copy SMILES
Affinity DataEC50:  3.30E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails