Compile Data Set for Download or QSAR
Found 167 Enz. Inhib. hit(s) with Target = 'Cystic fibrosis transmembrane conductance regulator [1-507,509-1480]'
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160509(US10280160, Example 1. | US9682969, 1)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160510(US10280160, Example 2. | US9682969, 2)copy SMILEScopy InChI
Affinity DataEC50:  1.50E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160511(US10280160, Example 3. | US9682969, 3)copy SMILEScopy InChI
Affinity DataEC50:  1.50E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160512(US10280160, Example 6. | US9682969, 4 | US9682969,...)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160513(US10280160, Example 5. | US9682969, 5)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160512(US10280160, Example 6. | US9682969, 4 | US9682969,...)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160515(US10280160, Example 9. | US9682969, 7 | US9682969,...)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160516(US10280160, Example 8. | US9682969, 8)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160515(US10280160, Example 9. | US9682969, 7 | US9682969,...)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160518(US10280160, Example 10. | US9682969, 10)copy SMILEScopy InChI
Affinity DataEC50:  1.50E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160519(US10280160, Example 11. | US9682969, 11)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160520(US10280160, Example 12. | US9682969, 12)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160521(US10280160, Example 13. | US9682969, 13)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160522(US10280160, Example 14. | US9682969, 14)copy SMILEScopy InChI
Affinity DataEC50:  1.50E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160523(US10280160, Example 15. | US9682969, 15)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160524(US10280160, Example 16. | US9682969, 16)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160525(US10280160, Example 22. | US9682969, 17 | US968296...)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160526(US10280160, Example 18. | US9682969, 18)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160527(US10280160, Example 19. | US9682969, 19)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160528(US10280160, Example 25. | US9682969, 20 | US968296...)copy SMILEScopy InChI
Affinity DataEC50:  1.50E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160529(US10280160, Example 21. | US9682969, 21)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160525(US10280160, Example 22. | US9682969, 17 | US968296...)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160531(US10280160, Example 24. | US9682969, 23 | US968296...)copy SMILEScopy InChI
Affinity DataEC50:  1.50E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160531(US10280160, Example 24. | US9682969, 23 | US968296...)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160528(US10280160, Example 25. | US9682969, 20 | US968296...)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160534(US10280160, Example 26. | US9682969, 26)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160535(US10280160, Example 27. | US9682969, 27)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160536(US10280160, Example 28. | US9682969, 28)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160537(US10280160, Example 29. | US9682969, 29)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160545(US10280160, Example 30. | US9682969, 30)copy SMILEScopy InChI
Affinity DataEC50:  1.50E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM160546(US10280160, Example 31. | US9682969, 31)copy SMILEScopy InChI
Affinity DataEC50: <1.00E+4nMAssay Description:This protocol is designed to selectively screen small molecule compounds for F508del CFTR corrector activities in the YFP (yellow fluorescent protein...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SQ8XKTUS Patent
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM576220(WO2022109573, Compound 4)copy SMILES
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3J78PubMed
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM576221(WO2022109573, Compound 7)copy SMILES
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3J78PubMed
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM576222(WO2022109573, Compound 8)copy SMILES
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3J78PubMed
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM576223(WO2022109573, Compound 9)copy SMILES
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3J78PubMed
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM576224(WO2022109573, Compound 13)copy SMILES
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3J78PubMed
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM576225(WO2022109573, Compound 14)copy SMILES
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3J78PubMed
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM576226(WO2022109573, Compound 17)copy SMILES
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3J78PubMed
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM576227(WO2022109573, Compound 18)copy SMILES
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3J78PubMed
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM576228(WO2022109573, Compound 19)copy SMILES
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3J78PubMed
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM576229(WO2022109573, Compound 21)copy SMILES
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3J78PubMed
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM576230(WO2022109573, Compound 23)copy SMILES
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3J78PubMed
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM576231(WO2022109573, Compound 24)copy SMILES
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3J78PubMed
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM576232(WO2022109573, Compound 25)copy SMILES
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3J78PubMed
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM576233(WO2022109573, Compound 29)copy SMILES
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3J78PubMed
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM576234(WO2022109573, Compound 31)copy SMILES
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3J78PubMed
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM576235(WO2022109573, Compound 32)copy SMILES
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3J78PubMed
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM576236(WO2022109573, Compound 34)copy SMILES
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3J78PubMed
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM576237(WO2022109573, Compound 36)copy SMILES
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3J78PubMed
TargetCystic fibrosis transmembrane conductance regulator [1-507,509-1480](Homo sapiens (Human))
Flatley Discovery Lab, LLC

US Patent
LigandPNGBDBM576238(WO2022109573, Compound 37)copy SMILES
Affinity DataEC50: <500nMAssay Description:ssing chamber experiments were performed using human bronchial epithelial (HBE) cells derived from CF subjects heterozygous for F508del and a minimal...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NK3J78PubMed
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