Compile Data Set for Download or QSAR
Found 203 Enz. Inhib. hit(s) with Target = 'Cyclin-dependent kinase 3'
TargetCyclin-dependent kinase 3(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50193090(CHEMBL3895785)copy SMILEScopy InChI
Affinity DataKi: >1.00E+3nMAssay Description:Inhibition of CDK3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73GP8PubMed
TargetCyclin-dependent kinase 3(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM12621(2,4-Diamino-5-ketopyrimidine 39 | 5-[(2,3-difluoro...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7MPDPubMed
LigandPNGBDBM601933(4-((6'-hydroxy-8'-oxo-7',8'-dihydro-6'H- spiro[cyc...)copy SMILES
Affinity DataIC50: 0.940nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibition of human CDK3/cyclin-E using histone H1 as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5KB8PubMed
LigandPNGBDBM50193093(RGB-286638)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of CDK3/cyclin E (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73GP8PubMed
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human CDK3/cyclin-E using histone H1 as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ650NPubMed
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human CDK3/cyclin-E using histone H1 as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ650NPubMed
LigandPNGBDBM601934(4-((7'-oxo-7',8'-dihydro-6'H- spiro[cyclohexane-1,...)copy SMILES
Affinity DataIC50: 2.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human CDK3/cyclin-E using histone H1 as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W380MTPubMed
LigandPNGBDBM50363196(CHEMBL1944698)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human full length C-terminal His6-tagged CDK3/N-terminal GST-tagged cyclin E expressed in baculovirus infected Sf21 insect ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73GP8PubMed
LigandPNGBDBM50059889((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of CDK3/Cyclin E (unknown origin)-mediated phosphorylation of peptide substrate incubated for 15 mins prior to substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MV7PubMed
LigandPNGBDBM601936(4-((1'H-spiro[cyclohexane-1,4'- pyrimido[5',4':4,5...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
TargetCyclin-dependent kinase 3(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50511926(CHEMBL4442620)copy SMILEScopy InChI
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23X8BM3PubMed
LigandPNGBDBM601941((S)-4-((6'-(fluoromethyl)-8'-oxo- 7',8'-dihydro-6'...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
LigandPNGBDBM601953(2'-((4-(piperazine-1- carbonyl)phenyl)amino)-7',8'...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
TargetCyclin-dependent kinase 3(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 6.90nMAssay Description:Inhibition of CDK3/Cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M94FZPubMed
LigandPNGBDBM50363196(CHEMBL1944698)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of C-terminal His6-tagged human CDK3/N-terminal GST-tagged human cyclin EMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56K3PubMed
LigandPNGBDBM50363196(CHEMBL1944698)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibition of recombinant human full-length C-terminal His6-tagged CDK3/full-length human N-terminal GST-tagged Cyclin E expressed in baculovirus inf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q21J2PubMed
LigandPNGBDBM601952(2'-((4-(4-methylpiperazine-1- carbonyl)phenyl)amin...)copy SMILES
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
LigandPNGBDBM59227(Pyrazolopyrimidone analog, RGB-286147)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of in vitro kinase activity of purified CDKs.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3BR6PubMed
LigandPNGBDBM50511926(CHEMBL4442620)copy SMILEScopy InChI
Affinity DataIC50: 9nMAssay Description:Inhibition of recombinant human full-length C-terminal His6-tagged CDK3/full-length human N-terminal GST-tagged Cyclin E expressed in baculovirus inf...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q21J2PubMed
LigandPNGBDBM601935(4-((3'-oxo-2',3'-dihydro-1'H- spiro[cyclohexane-1,...)copy SMILES
Affinity DataIC50: 9.90nMMore data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
LigandPNGBDBM601951(6'-hydroxy-2'-((4-(4- methylpiperazine-1- carbonyl...)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
LigandPNGBDBM601942(4-((8'-methyl-7'-oxo-7',8'-dihydro- 6'H-spiro[cycl...)copy SMILES
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
LigandPNGBDBM50573929(CHEMBL4848734)copy SMILES
Affinity DataIC50: 11nMAssay Description:Inhibition of human CDK3/cyclinE using Histone H1 as substrate incubated for 2 hrs by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6X2GPubMed
LigandPNGBDBM601946(4-((1',3'-dimethyl-1'H- spiro[cyclohexane-1,4'- py...)copy SMILES
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
LigandPNGBDBM601938((R)-4-((6'-(fluoromethyl)-8'-oxo- 7',8'-dihydro-6'...)copy SMILES
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
TargetCyclin-dependent kinase 3(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM454542(US10717746, Example 25 | US10717746, Example 84)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of CDK3 (unknown origin) in presence of 5 mM ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D8VPubMed
LigandPNGBDBM601949(2'-((4-((4-methylpiperazin-1- yl)sulfonyl)phenyl)a...)copy SMILES
Affinity DataIC50: 23nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
LigandPNGBDBM601940(4-((1'-methyl-1'H-spiro[cyclohexane-1,4'- pyrimido...)copy SMILES
Affinity DataIC50: 23nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
TargetCyclin-dependent kinase 3(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50528817(CHEMBL4462530 | US10717746, Example 14 | US2023041...)copy SMILEScopy InChI
Affinity DataIC50: 23nMAssay Description:Inhibition of CDK3 (unknown origin) in presence of 5 mM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D8VPubMed
LigandPNGBDBM601948(6'-hydroxy-2'-((4-((4- methylpiperazin-1- yl)sulfo...)copy SMILES
Affinity DataIC50: 28nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
LigandPNGBDBM601944(4-((6',8'-dimethyl-7'-oxo-7',8'- dihydro-6'H-spiro...)copy SMILES
Affinity DataIC50: 29nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
TargetCyclin-dependent kinase 3(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM50511931(CHEMBL4579344)copy SMILEScopy InChI
Affinity DataIC50: 29nMAssay Description:Inhibition of CDK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26Q21J2PubMed
LigandPNGBDBM601939((S)-4-((6'-methyl-8'-oxo-7',8'- dihydro-6'H-spiro[...)copy SMILES
Affinity DataIC50: 34nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
LigandPNGBDBM50433369(CHEMBL2377825)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibition of CDK3/Cyclin E (unknown origin)-mediated phosphorylation of peptide substrate incubated for 15 mins prior to substrate addition measured...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MV7PubMed
LigandPNGBDBM50573930(CHEMBL4856177)copy SMILES
Affinity DataIC50: 51nMAssay Description:Inhibition of human CDK3/cyclinE using Histone H1 as substrate incubated for 2 hrs by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZG6X2GPubMed
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibition of full length human recombinant CDK3/Cyclin E using histone H1 as substrate incubated for 40 mins in presence of [gamma-33ATP] by radiome...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ72D2PubMed
LigandPNGBDBM601954(8'-methyl-2'-((4-((4-methylpiperazin- 1-yl)sulfony...)copy SMILES
Affinity DataIC50: 57nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
TargetCyclin-dependent kinase 3(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)copy SMILEScopy InChI
Affinity DataIC50: 58nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7MPDPubMed
LigandPNGBDBM601955(7'-((4-(piperazine-1- carbonyl)phenyl)amino)-1',2'...)copy SMILES
Affinity DataIC50: 58nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
LigandPNGBDBM601937(4-((1'-methyl-3'-oxo-2',3'-dihydro-1'H- spiro[cycl...)copy SMILES
Affinity DataIC50: 59nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
LigandPNGBDBM601945(4-((3'-methyl-1'H-spiro[cyclohexane- 1,4'-pyrimido...)copy SMILES
Affinity DataIC50: 73nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
LigandPNGBDBM601950(7'-((4-(4-methylpiperazine-1- carbonyl)phenyl)amin...)copy SMILES
Affinity DataIC50: 75nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
TargetCyclin-dependent kinase 3(Homo sapiens (Human))
University of Nebraska Medical Center

Curated by ChEMBL
LigandPNGBDBM454519(US10717746, Example 2)copy SMILEScopy InChI
Affinity DataIC50: 84nMAssay Description:Inhibition of CDK3 (unknown origin) in presence of 5 mM ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90D8VPubMed
LigandPNGBDBM164883(US9067888, 33)copy SMILEScopy InChI
Affinity DataIC50: 94nMAssay Description:Inhibition of recombinant human CDK3/cyclin E expressed in baculovirus infected Sf9 insect cells after 80 mins in presence of [33P]ATP by microbeta s...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73GP8PubMed
LigandPNGBDBM601957(4-((3'-oxo-2',3'-dihydro-1'H- spiro[cyclohexane-1,...)copy SMILES
Affinity DataIC50: 96nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
LigandPNGBDBM601958(N-methyl-4-((3'-oxo-2',3'-dihydro- 1'H-spiro[cyclo...)copy SMILES
Affinity DataIC50: 105nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
LigandPNGBDBM601961(7'-((4-(morpholine-4- carbonyl)phenyl)amino)-1',2'...)copy SMILES
Affinity DataIC50: 106nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2VX0MGD
LigandPNGBDBM50563486(CHEMBL4757951)copy SMILES
Affinity DataIC50: 113nMAssay Description:Inhibition of CDK3/cyclin E1 (unknown origin) using FAM-labeled peptide and ATP as substrate preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3K3WPubMed
Displayed 1 to 50 (of 203 total ) | Next | Last >>
Jump to: