Compile Data Set for Download or QSAR
Found 3 Enz. Inhib. hit(s) with Target = 'Histone-lysine N-methyltransferase 2B'
TargetHistone-lysine N-methyltransferase 2B(Homo sapiens (Human))TBA
LigandPNGBDBM50572749(CHEMBL4854710)copy SMILES
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of MLL4 (unknown origin) using SAM as substrate preincubated for 10 mins followed by substrate addition measured after 4 hrs by HTRF metho...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HQ43QPPubMed
TargetHistone-lysine N-methyltransferase 2B(Homo sapiens (Human))TBA
LigandPNGBDBM50606100(CHEMBL5173004)copy SMILES
Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2DNQPubMed
TargetHistone-lysine N-methyltransferase 2B(Homo sapiens (Human))TBA
LigandPNGBDBM50400778(CHEMBL2204995)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of MLL4 using core histone as substrate preincubated for 10 mins followed by addition of [3H]SAM and incubated for 60 minsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3G60PubMed