Compile Data Set for Download or QSAR
Found 5 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase BTK/Lck'
TargetTyrosine-protein kinase BTK/Lck(Homo sapiens (Human))
ONO PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM194087(US20230364079, Example Tirabrutinib | US9199997, 9...)copy SMILEScopy InChI
Affinity DataIC50: 375nMT: 2°CAssay Description:The measurement of Btk enzyme inhibitory activity was performed using the following reagents: Z'-LYTE Kinase Assay Kit-Tyr 1 (containing Tyr 1 peptid...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GF0S90US Patent
TargetTyrosine-protein kinase BTK/Lck(Homo sapiens (Human))
ONO PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM275489(US9879013, 11(3))copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X63PZ1US Patent
TargetTyrosine-protein kinase BTK/Lck(Homo sapiens (Human))
ONO PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM275463(US9879013, 8)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+4nMAssay Description:The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X63PZ1US Patent
TargetTyrosine-protein kinase BTK/Lck(Homo sapiens (Human))
ONO PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM194087(US20230364079, Example Tirabrutinib | US9199997, 9...)copy SMILEScopy InChI
Affinity DataIC50: 1.14E+5nMAssay Description:The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X63PZ1US Patent
TargetTyrosine-protein kinase BTK/Lck(Homo sapiens (Human))
ONO PHARMACEUTICAL CO., LTD.

US Patent
LigandPNGBDBM275473(US9879013, 8(14))copy SMILEScopy InChI
Affinity DataIC50: 2.20E+5nMAssay Description:The Btk enzyme inhibitory activity was measured, based on the protocol provided by the manufacturer, using Btk (Invitrogen Corporation) and the ZR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X63PZ1US Patent