Compile Data Set for Download or QSAR
Found 94 Enz. Inhib. hit(s) with Target = 'Peptidyl-prolyl cis-trans isomerase D'
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)copy SMILEScopy InChI
Affinity DataKi:  2.60nMAssay Description:Binding affinity to human recombinant cyclophilin D by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6M8FPubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)copy SMILEScopy InChI
Affinity DataKi:  7nMAssay Description:Inhibition of fluorescein labeled cyclosporin binding to Cyp40 by flourescence polarization competition assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26110M8PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)copy SMILEScopy InChI
Affinity DataKi:  8.20nMAssay Description:Inhibition of Cyclophilin D (unknown origin) activity in absence of detergentMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CR6PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50339005(5-(4-((4R,5R,E)-5-((2S,5S,11S,14S,17S,20S,23R,26S,...)copy SMILEScopy InChI
Affinity DataKi:  12nMAssay Description:Inhibition of Cyclophilin 40 PPIase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26110M8PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)copy SMILEScopy InChI
Affinity DataKi:  34nMAssay Description:Inhibition of Cyclophilin 40 PPIase activityMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26110M8PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50164666(CHEMBL3799661)copy SMILEScopy InChI
Affinity DataKi:  99nMAssay Description:Inhibition of Cyclophilin D (unknown origin) activity preincubated for 15 mins followed Suc-AAPF-pNA substrate addition by chymotrypsin coupled based...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CR6PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50164670(CHEMBL3799597)copy SMILEScopy InChI
Affinity DataKi:  950nMAssay Description:Inhibition of Cyclophilin D (unknown origin) activity preincubated for 15 mins followed Suc-AAPF-pNA substrate addition by chymotrypsin coupled based...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CR6PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50169545(CHEMBL3805631)copy SMILEScopy InChI
Affinity DataKi:  1.33E+3nMAssay Description:Binding affinity to human recombinant cyclophilin D by surface plasmon resonance analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6M8FPubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50495808(CHEMBL1557710)copy SMILEScopy InChI
Affinity DataKi:  2.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM92912(Aryl 1-indanylketone, 1)copy SMILEScopy InChI
Affinity DataKi:  2.42E+3nM ΔG°:  -29.9kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34W26PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50164674(CHEMBL3799875)copy SMILEScopy InChI
Affinity DataKi:  2.60E+3nMAssay Description:Inhibition of Cyclophilin D (unknown origin) activity preincubated for 15 mins followed Suc-AAPF-pNA substrate addition by chymotrypsin coupled based...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CR6PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50613627(CHEMBL2006156)copy SMILES
Affinity DataKi:  3.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50613626(CHEMBL5275318)copy SMILES
Affinity DataKi:  3.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50164673(CHEMBL3797905)copy SMILEScopy InChI
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of Cyclophilin D (unknown origin) activity preincubated for 15 mins followed Suc-AAPF-pNA substrate addition by chymotrypsin coupled based...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CR6PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM139995(US8901295, F428)copy SMILEScopy InChI
Affinity DataKi:  5.90E+3nMAssay Description:Inhibition of Cyclophilin D (unknown origin) activity in absence of detergentMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CR6PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM139995(US8901295, F428)copy SMILEScopy InChI
Affinity DataKi:  5.90E+3nMAssay Description:Inhibition of Cyclophilin D (unknown origin) activity preincubated for 15 mins followed Suc-AAPF-pNA substrate addition by chymotrypsin coupled based...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CR6PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM92913(Aryl 1-indanylketone, 2)copy SMILEScopy InChI
Affinity DataKi:  6.28E+3nM ΔG°:  -27.7kJ/molepH: 7.8 T: 2°CAssay Description:PPIase activity assay were performed at 283 K in quartz cuvettes with a path length of 1 cm under vigorous stirring with a Hewlett-Packard 8453A UV-v...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2X34W26PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50164669(CHEMBL3798305)copy SMILEScopy InChI
Affinity DataKi:  9.10E+3nMAssay Description:Inhibition of Cyclophilin D (unknown origin) activity preincubated for 15 mins followed Suc-AAPF-pNA substrate addition by chymotrypsin coupled based...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CR6PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50164671(CHEMBL3798030)copy SMILEScopy InChI
Affinity DataKi:  2.20E+4nMAssay Description:Inhibition of Cyclophilin D (unknown origin) activity preincubated for 15 mins followed Suc-AAPF-pNA substrate addition by chymotrypsin coupled based...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CR6PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50164665(CHEMBL3797675)copy SMILEScopy InChI
Affinity DataKi:  6.30E+4nMAssay Description:Inhibition of Cyclophilin D (unknown origin) activity preincubated for 15 mins followed Suc-AAPF-pNA substrate addition by chymotrypsin coupled based...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474CR6PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)copy SMILEScopy InChI
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human recombinant cyclophilin D using Suc-AAPF-MCA as substrate preincubated for 1 hr followed by substrate addition measured per milli...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6M8FPubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516083(CHEMBL4470490)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibition of CypD (unknown origin) PPIase activity using N-Suc-AAPF-p-nitroanilide as substrate preincubated with enzyme for 10 mins followed by chy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2DZ2PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516083(CHEMBL4470490)copy SMILEScopy InChI
Affinity DataIC50: 60nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2DZ2PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516100(CHEMBL4466871)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2DZ2PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516080(CHEMBL4464178)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibition of CypD (unknown origin) PPIase activity using N-Suc-AAPF-p-nitroanilide as substrate preincubated with enzyme for 10 mins followed by chy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2DZ2PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM140005(US8901295, F684)copy SMILEScopy InChI
Affinity DataIC50: 640nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PGSUS Patent
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM140008(US8901295, F716)copy SMILEScopy InChI
Affinity DataIC50: 660nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PGSUS Patent
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516098(CHEMBL4547673)copy SMILEScopy InChI
Affinity DataIC50: 735nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2DZ2PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM140007(US8901295, F714)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PGSUS Patent
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM140004(US8901295, F680)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PGSUS Patent
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516080(CHEMBL4464178)copy SMILEScopy InChI
Affinity DataIC50: 1.35E+3nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2DZ2PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM140002(US8901295, F671)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PGSUS Patent
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50169545(CHEMBL3805631)copy SMILEScopy InChI
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of human recombinant cyclophilin D using Suc-AAPF-MCA as substrate preincubated for 1 hr followed by substrate addition measured per milli...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24T6M8FPubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516082(CHEMBL4464825)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CypD (unknown origin) PPIase activity using N-Suc-AAPF-p-nitroanilide as substrate preincubated with enzyme for 10 mins followed by chy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2DZ2PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516095(CHEMBL4451136)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2DZ2PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516084(CHEMBL4520315)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2DZ2PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516082(CHEMBL4464825)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2DZ2PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50381013(CHEMBL2017129)copy SMILEScopy InChI
Affinity DataIC50: 2.42E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516087(CHEMBL4471175)copy SMILEScopy InChI
Affinity DataIC50: 2.80E+3nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2DZ2PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM140006(US8901295, F712)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PGSUS Patent
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516096(CHEMBL4540033)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2DZ2PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516094(CHEMBL4453162)copy SMILEScopy InChI
Affinity DataIC50: 3.60E+3nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2DZ2PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516090(CHEMBL4563478)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Displacement of fluorescein labelled cyclosporine A derivative from human recombinant CypD (30 to 207 residues) expressed in Escherichia coli cells i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2DZ2PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM140003(US8901295, F673)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PGSUS Patent
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM139995(US8901295, F428)copy SMILEScopy InChI
Affinity DataIC50: 6.20E+3nMpH: 7.8 T: 2°CAssay Description:Cyclophilin PPlase activity was measured at 20 C. by using the standard chymotrypsin coupled assay (Kofron J L, Kuzmic P, Kishore V, Colon-Bonilla E,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PGSUS Patent
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM92913(Aryl 1-indanylketone, 2)copy SMILEScopy InChI
Affinity DataIC50: 6.28E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM50516096(CHEMBL4540033)copy SMILEScopy InChI
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of CypD (unknown origin) PPIase activity using N-Suc-AAPF-p-nitroanilide as substrate preincubated with enzyme for 10 mins followed by chy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JM2DZ2PubMed
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM394270(US9975902, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The binding capacity of the compounds was measured using a competition Fluorescence-Polarisation based assay with fluorescine labelled cyclosporin.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9DD6US Patent
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM394272(US9975902, Example 2)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The binding capacity of the compounds was measured using a competition Fluorescence-Polarisation based assay with fluorescine labelled cyclosporin.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9DD6US Patent
TargetPeptidyl-prolyl cis-trans isomerase D(Homo sapiens (Human))
University of Kansas

Curated by ChEMBL
LigandPNGBDBM394272(US9975902, Example 2)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:The peptidyl-proline isomerase activity (PPase) was determined by using a PPase-chymotrypsin coupled assay with suc-AAPF-p-NA as substrated and color...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26W9DD6US Patent
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