Compile Data Set for Download or QSAR
Found 228 Enz. Inhib. hit(s) with Target = 'Cholesterol side-chain cleavage enzyme, mitochondrial'
LigandPNGBDBM83720(6-(2-naphthalenylsulfonyl)quinazoline-2,4-diamine ...)copy SMILEScopy InChI
Affinity DataIC50: 0.0200nMAssay Description:Antibacterial activity against Streptococcus faecalis assessed as growth inhibitionMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28S4SWQPubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
CORTENDO AB (PUBL)

US Patent
LigandPNGBDBM330393(US9725436, Entry 12)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD211NUS Patent
LigandPNGBDBM50614282(CHEMBL5279964)copy SMILES
Affinity DataIC50: 6.90nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
LigandPNGBDBM50614275(CHEMBL5277226)copy SMILES
Affinity DataIC50: 9.20nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
LigandPNGBDBM50614276(CHEMBL5286888)copy SMILES
Affinity DataIC50: 9.90nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
LigandPNGBDBM50614279(CHEMBL5279347)copy SMILES
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
LigandPNGBDBM50614277(CHEMBL5267440)copy SMILES
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
LigandPNGBDBM50614431(CHEMBL5289236)copy SMILES
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
LigandPNGBDBM50614280(CHEMBL5276161)copy SMILES
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
LigandPNGBDBM50614274(CHEMBL5272543)copy SMILES
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
LigandPNGBDBM50614281(CHEMBL5288022)copy SMILES
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
LigandPNGBDBM50614278(CHEMBL5285039)copy SMILES
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
CORTENDO AB (PUBL)

US Patent
LigandPNGBDBM330396(US9725436, Entry 15)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD211NUS Patent
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
CORTENDO AB (PUBL)

US Patent
LigandPNGBDBM330382(US9725436, Entry 2)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD211NUS Patent
LigandPNGBDBM50350465(AMPICILLIN | AY-6108 | Amcill | Aminobenzylpenicil...)copy SMILEScopy InChI
Affinity DataIC50: 28.6nMAssay Description:Antibacterial activity against Streptococcus faecalis by broth microdilution techniqueMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6GNNPubMed
LigandPNGBDBM21690(1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,...)copy SMILEScopy InChI
Affinity DataIC50: 36.2nMAssay Description:Antibacterial activity against Enterococcus faecalis MTCC 439 incubated overnight by broth dilution techniqueMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7SD8PubMed
LigandPNGBDBM50335519((S)-3,6-Diamino-hexanoic acid {(3S,9S,12S,15S)-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 41.4nMAssay Description:Antibacterial activity against gram positive bacteria Enterococcus faecalis was determined by twofold Micro-broth dilution assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2JZ3PubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
CORTENDO AB (PUBL)

US Patent
LigandPNGBDBM330392(US9725436, Entry 11)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD211NUS Patent
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
CORTENDO AB (PUBL)

US Patent
LigandPNGBDBM330388(US9725436, Entry 7)copy SMILEScopy InChI
Affinity DataIC50: 51nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD211NUS Patent
LigandPNGBDBM50614273(CHEMBL5279536)copy SMILES
Affinity DataIC50: 53nMMore data for this Ligand-Target Pair
Ligand Info
In DepthDetails
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
CORTENDO AB (PUBL)

US Patent
LigandPNGBDBM330389(US9725436, Entry 8)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD211NUS Patent
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
CORTENDO AB (PUBL)

US Patent
LigandPNGBDBM330397(US9725436, Entry 16)copy SMILEScopy InChI
Affinity DataIC50: 73nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD211NUS Patent
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
CORTENDO AB (PUBL)

US Patent
LigandPNGBDBM330395(US9725436, Entry 14)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD211NUS Patent
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
CORTENDO AB (PUBL)

US Patent
LigandPNGBDBM330398(US9725436, Entry 17)copy SMILEScopy InChI
Affinity DataIC50: 130nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD211NUS Patent
LigandPNGBDBM50498223(CHEMBL3577359)copy SMILEScopy InChI
Affinity DataIC50: 167nMAssay Description:Antibacterial activity against Enterococcus faecalis ATCC 51299 assessed as growth inhibition using fresh sample in DMSO by CLSI methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5R6XPubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
CORTENDO AB (PUBL)

US Patent
LigandPNGBDBM330383(US9725436, Entry 3)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD211NUS Patent
LigandPNGBDBM50225960(CHEMBL310176)copy SMILEScopy InChI
Affinity DataIC50: 219nMAssay Description:Concentration (IC50) to inhibit the growth of Streptococcus faecalis.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2X9WPubMed
LigandPNGBDBM50225959(CHEMBL307316)copy SMILEScopy InChI
Affinity DataIC50: 401nMAssay Description:Concentration (IC50) to inhibit the growth of Streptococcus faecalis.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27D2X9WPubMed
LigandPNGBDBM50476074(Gentamicin | SCH-9724 | Uromycine)copy SMILEScopy InChI
Affinity DataIC50: 445nMAssay Description:Antibacterial activity against Streptococcus faecalis by broth microdilution techniqueMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MK6GNNPubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
CORTENDO AB (PUBL)

US Patent
LigandPNGBDBM330384(US9725436, Entry 4)copy SMILEScopy InChI
Affinity DataIC50: 450nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD211NUS Patent
LigandPNGBDBM50600678(CHEMBL5176174)copy SMILES
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H9997NPubMed
LigandPNGBDBM21690(1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,...)copy SMILEScopy InChI
Affinity DataIC50: 603nMAssay Description:Antibacterial activity against Enterococcus faecalis ATCC 51299 assessed as growth inhibition using fresh sample in DMSO by CLSI methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5R6XPubMed
LigandPNGBDBM50366826(DR-3355 | Floxacin | Iquix | LEVOFLOXACIN | Levaqu...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Antibacterial activity against vancomycin-sensitive Enterococcus faecalis ATCC 29212 after 18 hrs by broth microdilution methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280BKRPubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
CORTENDO AB (PUBL)

US Patent
LigandPNGBDBM50094191(17-Aziridin-2-ylmethyl-10,13-dimethyl-2,3,4,7,8,9,...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of P450 sccMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25H7FH3PubMed
LigandPNGBDBM50366826(DR-3355 | Floxacin | Iquix | LEVOFLOXACIN | Levaqu...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51299 after 18 hrs by broth microdilution methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280BKRPubMed
LigandPNGBDBM50509323(CHEMBL4436622)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Antibacterial activity against vancomycin-resistant Enterococcus faecalis AUS-RBWH-VRE-01 assessed as reduction in fungal growth incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5KB8PubMed
LigandPNGBDBM50366826(DR-3355 | Floxacin | Iquix | LEVOFLOXACIN | Levaqu...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+3nMAssay Description:Antibacterial activity against vancomycin-sensitive Enterococcus faecalis 12-5 after 18 hrs by broth microdilution methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2280BKRPubMed
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)copy SMILEScopy InChI
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of cholesterol side chain cleavage cytochrome P450More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7SZTPubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
CORTENDO AB (PUBL)

US Patent
LigandPNGBDBM330381(US9725436, Entry 1)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD211NUS Patent
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
CORTENDO AB (PUBL)

US Patent
LigandPNGBDBM330394(US9725436, Entry 13)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD211NUS Patent
LigandPNGBDBM50497194(CHEMBL3116168)copy SMILEScopy InChI
Affinity DataIC50: 1.44E+3nMAssay Description:Antimicrobial activity against Enterococcus faecalis assessed as inhibition of biofilm formation after 20 hrs by crystal violet staining analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4F6VPubMed
LigandPNGBDBM50237605(Achromycin | Achromycin V | CHEBI:27902 | Cyclopar...)copy SMILEScopy InChI
Affinity DataIC50: 1.57E+3nMAssay Description:Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51299 after 18 hrs by broth dilution assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6FNXPubMed
LigandPNGBDBM50509324(CHEMBL4463460)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Antibacterial activity against vancomycin-resistant Enterococcus faecalis AUS-RBWH-VRE-01 assessed as reduction in fungal growth incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5KB8PubMed
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
CORTENDO AB (PUBL)

US Patent
LigandPNGBDBM330386(US9725436, Entry 6)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+3nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD211NUS Patent
LigandPNGBDBM50478886(CHEMBL501116)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51299 after 18 hrs by broth dilution assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22J6FNXPubMed
LigandPNGBDBM50497201(CHEMBL3116167)copy SMILEScopy InChI
Affinity DataIC50: 2.17E+3nMAssay Description:Antimicrobial activity against Enterococcus faecalis assessed as inhibition of biofilm formation after 20 hrs by crystal violet staining analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4F6VPubMed
LigandPNGBDBM50103513(CHEBI:17076 | Chemform | Gerox | NSC-14083 | Strep...)copy SMILEScopy InChI
Affinity DataIC50: 2.23E+3nMAssay Description:Antibacterial activity against gram positive bacteria Enterococcus faecalis was determined by twofold Micro-broth dilution assayMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FJ2JZ3PubMed
LigandPNGBDBM50499513(CHEMBL4299436)copy SMILEScopy InChI
Affinity DataIC50: 2.27E+3nMAssay Description:Antibacterial activity against low level vancomycin-resistant Enterococcus faecalis ATCC 51299 by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M61P8HPubMed
LigandPNGBDBM50497203(CHEMBL3115985)copy SMILEScopy InChI
Affinity DataIC50: 2.29E+3nMAssay Description:Antimicrobial activity against Enterococcus faecalis assessed as inhibition of biofilm formation after 20 hrs by crystal violet staining analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29K4F6VPubMed
LigandPNGBDBM50335519((S)-3,6-Diamino-hexanoic acid {(3S,9S,12S,15S)-3-(...)copy SMILEScopy InChI
Affinity DataIC50: 2.34E+3nMAssay Description:Antibacterial activity against Enterococcus faecalis ATCC 51299 assessed as growth inhibition using fresh sample in DMSO by CLSI methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5R6XPubMed
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