Compile Data Set for Download or QSAR
Found 97 Enz. Inhib. hit(s) with Target = 'Rhodopsin kinase GRK7'
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human GRK7 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DJ5KB8PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataIC50: 6nMAssay Description:Inhibition of human GRK7 using casein as substrate by [gamma-33P]-ATP assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W380MTPubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50566949(CHEMBL4877302)copy SMILES
Affinity DataIC50: 6.40nMAssay Description:Inhibition of recombinant full length human GRK7 using casein as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2D97PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50566946(CHEMBL4854871)copy SMILES
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant full length human GRK7 using casein as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2D97PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50566947(CHEMBL4847703)copy SMILES
Affinity DataIC50: 36nMAssay Description:Inhibition of recombinant full length human GRK7 using casein as substrate incubated for 40 mins in presence of [gamma-33ATP] by scintillation counti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K2D97PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM3149(2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzen...)copy SMILEScopy InChI
Affinity DataIC50: 180nMAssay Description:Inhibition of GRK7-mediated bovine tubulin phosphorylation by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2P26Z8ZPubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50257340(CHEMBL4072828)copy SMILEScopy InChI
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK7 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280552ZPubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50257328(CHEMBL4082775)copy SMILEScopy InChI
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK7 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280552ZPubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50554257(CHEMBL4742990)copy SMILES
Affinity DataIC50: 9.14E+3nMAssay Description:Inhibition of human GRK7More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H135PSPubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50519662(CHEMBL4438748)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length human GRK7 using casein as substrate after 40 mins in presence of [gamma-33ATP] by radiometric scintillation co...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC93FGPubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50554258(CHEMBL4744858)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GRK7More data for this Ligand-Target Pair
Ligand InfoMCE
PC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H135PSPubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50135286(CHEMBL3745885)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human GRK7 using casein as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24Q7WT8PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50257344(CHEMBL4065690)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK7 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280552ZPubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50257350(CHEMBL1738877)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK7 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280552ZPubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50257350(CHEMBL1738877)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22Z19M2PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50257351(CHEMBL4095595)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK7 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280552ZPubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50257365(CHEMBL4083276)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human full length GST-tagged GRK7 expressed in baculovirus using ulight topo2alpha as substrate preincubated for 60 mins fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q280552ZPubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50537742(CHEMBL4634634 | US11179389, Compound 1-14)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of recombinant full length human GST-tagged GRK7 expressed in baculovirus expression system using serine/threonine-16 peptide as substrate...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5CZGPubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50326053(CHEMBL608533 | PKC-412)copy SMILEScopy InChI
Affinity DataKd:  48nMAssay Description:Binding affinity to GRK7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI
Affinity DataKd:  7.20nMAssay Description:Binding affinity to GRK7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50326053(CHEMBL608533 | PKC-412)copy SMILEScopy InChI
Affinity DataKd:  48nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)copy SMILEScopy InChI
Affinity DataKd:  0.860nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50308060(16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,1...)copy SMILEScopy InChI
Affinity DataKd:  7.20nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50026612(BIBF-1120 | Nintedanib | US10981896, Compound Nint...)copy SMILEScopy InChI
Affinity DataKd:  1.20E+3nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)copy SMILEScopy InChI
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to GRK7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM4814(CHEMBL535 | N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fl...)copy SMILEScopy InChI
Affinity DataKd:  180nMAssay Description:Binding affinity to GRK7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50326054(CHEMBL1240703)copy SMILEScopy InChI
Affinity DataKd:  550nMAssay Description:Binding affinity to GRK7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM13535(4-[6-methoxy-7-(3-piperidin-1-ylpropoxy)quinazolin...)copy SMILEScopy InChI
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to GRK7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM16673(4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamo...)copy SMILEScopy InChI
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to GRK7More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PN95V2PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)copy SMILEScopy InChI
Affinity DataKd:  980nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50331096(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxy-7...)copy SMILEScopy InChI
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50332294(CHEMBL1287853 | N-tert-butyl-3-(5-methyl-2-(4-(2-(...)copy SMILEScopy InChI
Affinity DataKd:  2.60E+3nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM31095(5-[(Z)-(5-fluoranyl-2-oxidanylidene-1H-indol-3-yli...)copy SMILEScopy InChI
Affinity DataKd:  470nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM25121(4-{[(7R)-8-cyclopentyl-7-ethyl-5-methyl-6-oxo-5,6,...)copy SMILEScopy InChI
Affinity DataKd:  850nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50128285(3-(1-Methyl-1H-indol-3-yl)-4-[1-(1-pyridin-2-ylmet...)copy SMILEScopy InChI
Affinity DataKd:  1.30E+3nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)copy SMILEScopy InChI
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)copy SMILEScopy InChI
Affinity DataKd:  4.30E+3nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM17055((18S)-18-[(dimethylamino)methyl]-17-oxa-4,14,21-tr...)copy SMILEScopy InChI
Affinity DataKd:  310nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM27817(2-{[2-({1-[2-(dimethylamino)acetyl]-5-methoxy-2,3-...)copy SMILEScopy InChI
Affinity DataKd:  540nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50306682((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)copy SMILEScopy InChI
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM25118((3Z)-4-amino-5-fluoro-3-[5-(4-methylpiperazino)-1,...)copy SMILEScopy InChI
Affinity DataKd:  1.30E+3nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM15244(5-(2,6-dichlorophenyl)-2-(2,4-difluorophenyl)sulfa...)copy SMILEScopy InChI
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50184807((R)-1-(4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-5-me...)copy SMILEScopy InChI
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM26300(2-{3-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}qu...)copy SMILEScopy InChI
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM36409(2-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin...)copy SMILEScopy InChI
Affinity DataKd:  1.40E+3nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM5445(CHEMBL554 | GW572016 | LAPATINIB DITOSYLATE | Lapa...)copy SMILEScopy InChI
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50355504(CHEMBL1908393)copy SMILEScopy InChI
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM5447(CHEMBL939 | GEFITINIB | Iressa | N-(3-Chloro-4-flu...)copy SMILEScopy InChI
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM50322823((S)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahy...)copy SMILEScopy InChI
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
TargetRhodopsin kinase GRK7(Homo sapiens (Human))TBA
LigandPNGBDBM24654(4-N-(2,6-dichlorobenzene)-3-N-(piperidin-4-yl)-1H-...)copy SMILEScopy InChI
Affinity DataKd: >1.00E+4nMAssay Description:Binding constant for GRK7 kinase domainMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25D8S70PubMed
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