Compile Data Set for Download or QSAR
Found 18 Enz. Inhib. hit(s) with Target = 'Geranylgeranyl pyrophosphate synthase BTS1'
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25297(1-(2-hydrogen phosphonato-2-hydroxy-2-phosphonoeth...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25266(BPH-628 | bisphosphonate, 21 | {1-hydroxy-2-[3-(4-...)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25279(BPH-608 | bisphosphonate, 31 | {1-hydroxy-2-[3-(3-...)copy SMILEScopy InChI
Affinity DataKi:  30nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25289(bisphosphonate, 38 | {1-hydroxy-2-[3-(3-phenylphen...)copy SMILEScopy InChI
Affinity DataKi:  60nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25284((1-hydroxy-2-{3-[3-(naphthalene-2-sulfonamido)phen...)copy SMILEScopy InChI
Affinity DataKi:  80nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25288(BPH-629 | [1-hydroxy-2-(3-{8-oxatricyclo[7.4.0.0^{...)copy SMILEScopy InChI
Affinity DataKi:  110nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25308((1-hydroxy-2-{imidazo[1,2-a]pyridin-3-yl}-1-phosph...)copy SMILEScopy InChI
Affinity DataKi:  130nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)copy SMILEScopy InChI
Affinity DataKi:  260nMAssay Description:Binding affinity to Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25297(1-(2-hydrogen phosphonato-2-hydroxy-2-phosphonoeth...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25266(BPH-628 | bisphosphonate, 21 | {1-hydroxy-2-[3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25279(BPH-608 | bisphosphonate, 31 | {1-hydroxy-2-[3-(3-...)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25289(bisphosphonate, 38 | {1-hydroxy-2-[3-(3-phenylphen...)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MW2J2FPubMed
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25284((1-hydroxy-2-{3-[3-(naphthalene-2-sulfonamido)phen...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25288(BPH-629 | [1-hydroxy-2-(3-{8-oxatricyclo[7.4.0.0^{...)copy SMILEScopy InChI
Affinity DataIC50: 280nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM25308((1-hydroxy-2-{imidazo[1,2-a]pyridin-3-yl}-1-phosph...)copy SMILEScopy InChI
Affinity DataIC50: 340nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)copy SMILEScopy InChI
Affinity DataIC50: 660nMAssay Description:To measure the kinetic constants by radioactive assays, 0.2 μM wild-type E. coli OPPS and the wild-type or mutant S. cerevisiae GGPPS and human ...More data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1(Saccharomyces cerevisiae (Yeast))
Institute of Biological Chemistry

Curated by ChEMBL
LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)copy SMILEScopy InChI
Affinity DataIC50: 660nMAssay Description:Inhibition of Saccharomyces cerevisiae GGPPSMore data for this Ligand-Target Pair
TargetGeranylgeranyl pyrophosphate synthase BTS1 [Y107A,F108A](Saccharomyces cerevisiae (Yeast))
Academia Sinica

LigandPNGBDBM12578(2-(imidazol-1-yl)-1-hydroxyethylidene-1,1-bisphosp...)copy SMILEScopy InChI
Affinity DataIC50: 710nMAssay Description:The assays were performed by mixing either 0.2 μM E. coli OPPS, Y107A/F108A S. cerevisiae GGPPS, or Y96A/F97A human GGPPS with various concentra...More data for this Ligand-Target Pair