Compile Data Set for Download or QSAR
Found 9 Enz. Inhib. hit(s) with Target = 'ATP-binding cassette sub-family C member 5'
TargetATP-binding cassette sub-family C member 5(Homo sapiens (Human))
University of Troms£

Curated by ChEMBL
LigandPNGBDBM54115(5-[4-Ethoxy-3-(1-methyl-7-oxo-3-propyl-6,7-dihydro...)copy SMILEScopy InChI
Affinity DataKi:  65.3nMAssay Description:Inhibition of ABCC5 in human erythrocytes assessed as inhibition of ATP-mediated [3H]cGMP uptake in inside-out vesicles after 60 mins by liquid scint...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SX6F89PubMed
TargetATP-binding cassette sub-family C member 5(Homo sapiens (Human))
University of Troms£

Curated by ChEMBL
LigandPNGBDBM50386476(CHEMBL2047880)copy SMILEScopy InChI
Affinity DataKi:  75.3nMAssay Description:Inhibition of ABCC5 in human erythrocytes assessed as inhibition of ATP-mediated [3H]cGMP uptake in inside-out vesicles after 60 mins by liquid scint...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SX6F89PubMed
TargetATP-binding cassette sub-family C member 5(Homo sapiens (Human))
University of Troms£

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of ABCC5 in human erythrocytes assessed as inhibition of ATP-mediated [3H]cGMP uptake in inside-out vesicles after 60 mins by liquid scint...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SX6F89PubMed
TargetATP-binding cassette sub-family C member 5(Homo sapiens (Human))
University of Troms£

Curated by ChEMBL
LigandPNGBDBM50017103(9,10-Dimethoxy-3-methyl-2-(2,4,6-trimethyl-phenyli...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP5-expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KH0PMDPubMed
TargetATP-binding cassette sub-family C member 5(Homo sapiens (Human))
University of Troms£

Curated by ChEMBL
LigandPNGBDBM23620(2-({6-[bis(2-hydroxyethyl)amino]-4,8-bis(piperidin...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP5-expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KH0PMDPubMedDrugBank
TargetATP-binding cassette sub-family C member 5(Homo sapiens (Human))
University of Troms£

Curated by ChEMBL
LigandPNGBDBM50001285((E)-3-((3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)(...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP5-expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KH0PMDPubMed
TargetATP-binding cassette sub-family C member 5(Homo sapiens (Human))
University of Troms£

Curated by ChEMBL
LigandPNGBDBM50017691(CHEMBL126075 | dilazep)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP5-expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KH0PMDPubMed
TargetATP-binding cassette sub-family C member 5(Homo sapiens (Human))
University of Troms£

Curated by ChEMBL
LigandPNGBDBM14390(5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...)copy SMILEScopy InChI
Affinity DataIC50: 8.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of 9-(2-phosphonomethoxyethyl)adenine(PMEA) efflux (PMEA: 1 uM) in MRP5-expressing HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KH0PMDPubMed
TargetATP-binding cassette sub-family C member 5(Homo sapiens (Human))
University of Troms£

Curated by ChEMBL
LigandPNGBDBM50237626(Anturan | Anturane | CHEBI:9342 | Sulfinpyrazone |...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:TP_TRANSPORTER: inhibition of PMEA efflux (PMEA: 1 uM) in MRP5-expressing MDCKII cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4ZN1PubMed