Compile Data Set for Download or QSAR
Found 152 of ic50 for UniProtKB: P05181
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366426(CHEMBL4161819)copy SMILEScopy InChI
Affinity DataIC50: 230nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by addition of NADPH-regenerating sy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69B5PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158914(3-(1-Benzyl-1H-imidazol-4-yl)-pyridine | CHEMBL178...)copy SMILEScopy InChI
Affinity DataIC50: 580nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2E1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T154DBPubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50110231(3-(3-Nitro-phenyl)-3-{2-[4-(pyridin-2-ylamino)-but...)copy SMILEScopy InChI
Affinity DataIC50: 850nMAssay Description:The interaction of SC12 with cytochrome P450 enzymes was tested using Fluorescent High Throughput P450 assays (Gentest); The IC50s of the compounds w...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9P8SUS Patent
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50010231(CHEMBL107217 | Ditiocarb sodium | Sodium salt of D...)copy SMILEScopy InChI
Affinity DataIC50: 850nMT: 2°CAssay Description:The interaction of SC12 with cytochrome P450 enzymes was tested using Fluorescent High Throughput P450 assays (Gentest); The IC50s of the compounds w...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27T2WUS Patent
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158925(Bis-(5-pyridin-3-yl-thiophen-2-ylmethyl)-amine | C...)copy SMILEScopy InChI
Affinity DataIC50: 860nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2E1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T154DBPubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366334(CHEMBL4173133)copy SMILEScopy InChI
Affinity DataIC50: 920nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by addition of NADPH-regenerating sy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69B5PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366407(CHEMBL4169324)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by addition of NADPH-regenerating sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69B5PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366379(CHEMBL4165249)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by addition of NADPH-regenerating sy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69B5PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366401(CHEMBL4169721)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by addition of NADPH-regenerating sy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69B5PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366410(CHEMBL4163694)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by addition of NADPH-regenerating sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69B5PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366393(CHEMBL4176100)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by addition of NADPH-regenerating sy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69B5PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366399(CHEMBL4168669)copy SMILEScopy InChI
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by addition of NADPH-regenerating sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69B5PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158920(3-(3-Methyl-1H-imidazol-4-yl)-pyridine | CHEMBL179...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2E1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T154DBPubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM12352(3-(1-methyl-1H-imidazol-4-yl)pyridine | CHEMBL3609...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2E1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T154DBPubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158919(3-Thiophen-2-yl-pyridine | CHEMBL179618 | US860970...)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2E1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T154DBPubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158923(5-Pyridin-3-yl-thiophene-2-carbaldehyde oxime | CH...)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2E1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T154DBPubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366406(CHEMBL4174365)copy SMILEScopy InChI
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by addition of NADPH-regenerating sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69B5PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366402(CHEMBL4172462)copy SMILEScopy InChI
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by addition of NADPH-regenerating sy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69B5PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM19188(7-(3-chlorobenzyloxy)-4-(methylamino)methyl-coumar...)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant CYP2E1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR2VJ6PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366411(CHEMBL4160749)copy SMILEScopy InChI
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by addition of NADPH-regenerating sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69B5PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366404(CHEMBL4162449)copy SMILEScopy InChI
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by addition of NADPH-regenerating sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69B5PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM12358(3-(4-methylthiophen-3-yl)pyridine | CHEMBL179704 |...)copy SMILEScopy InChI
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2E1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T154DBPubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366395(CHEMBL4175869)copy SMILEScopy InChI
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by addition of NADPH-regenerating sy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69B5PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM12351(3-(3-methylthiophen-2-yl)pyridine | CHEMBL179669 |...)copy SMILEScopy InChI
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2E1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T154DBPubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366394(CHEMBL4159065)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by addition of NADPH-regenerating sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69B5PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50158913(2-Fluoro-5-thiophen-3-yl-pyridine | CHEMBL179005 |...)copy SMILEScopy InChI
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2E1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T154DBPubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM190404(US9180183, SC12)copy SMILES
Affinity DataIC50: 9.20E+3nMT: 2°CAssay Description:The interaction of SC12 with cytochrome P450 enzymes was tested using Fluorescent High Throughput P450 assays (Gentest); The IC50s of the compounds w...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2B27T2WUS Patent
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM189322(US9173935, SC12)copy SMILES
Affinity DataIC50: 9.20E+3nMAssay Description:The interaction of SC12 with cytochrome P450 enzymes was tested using Fluorescent High Throughput P450 assays (Gentest); The IC50s of the compounds w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9P8SUS Patent
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366435(CHEMBL4161400)copy SMILEScopy InChI
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by addition of NADPH-regenerating sy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69B5PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50017203(CHEMBL3287379)copy SMILEScopy InChI
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of CYP2E1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M90B64PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50341409(CHEMBL4176771 | US11534443, Example 9)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes assessed as reduction in 6-Hydroxychlorzoxazone formation using chlorzoxazone as substrate after 10 to...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7CNPPubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50549522(CHEMBL4786038)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by NADPH generating system addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GH9NJKPubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50517497(CHEMBL4593911)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2E1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD152GPubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50452361(CHEMBL4218749)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP2E1 expressed in yeast cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP55TTPubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50566788(CHEMBL4850531)copy SMILES
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by NADPH addition by LC-MS/MS analys...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8Z07PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50396352(CHEMBL2170062)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant CYP2E1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89DJMPubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50341416(CHEMBL4174909 | US11534443, Example 32)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes assessed as reduction in 6-Hydroxychlorzoxazone formation using chlorzoxazone as substrate after 10 to...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7CNPPubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50341408(CHEMBL4166594 | US11534443, Example 29)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes assessed as reduction in 6-Hydroxychlorzoxazone formation using chlorzoxazone as substrate after 10 to...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7CNPPubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50341410(CHEMBL4166144 | US11534443, Example 1)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes assessed as reduction in 6-Hydroxychlorzoxazone formation using chlorzoxazone as substrate after 10 to...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28K7CNPPubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50236754(CHEMBL4082473)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Herpes simplex virus type 1 thymidine kinase(HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27S7R1XPubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50396352(CHEMBL2170062)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z89DJMPubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366392(CHEMBL4172417)copy SMILEScopy InChI
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by addition of NADPH-regenerating sy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69B5PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50536234(CHEMBL4580214)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CYP2E1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23T9MQ3PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366398(CHEMBL4164113)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by addition of NADPH-regenerating sy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69B5PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366405(CHEMBL4175429)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by addition of NADPH-regenerating sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69B5PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366337(CHEMBL4167560)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by addition of NADPH-regenerating sy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69B5PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM12348(3-(pyridin-3-yl)prop-2-yn-1-amine | CHEMBL360541 |...)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by addition of NADPH-regenerating sy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69B5PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366391(CHEMBL4173088)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using chlorzoxazone as substrate preincubated for 5 mins followed by addition of NADPH-regenerating sy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2QN69B5PubMed
TargetCytochrome P450 2E1(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50438845(CHEMBL2413882)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes assessed as chlorzoxazone 6-hydroxylation after 20 mins by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WH2RD3PubMed
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