Compile Data Set for Download or QSAR
Found 37 of ec50 for UniProtKB: P05556
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50535742(CHEMBL4592659)copy SMILEScopy InChI
Affinity DataEC50:  5.40nMAssay Description:Antagonist activity at integrin alpha4beta1 expressed in human Jurkat cells assessed as reduction in cell adhesion to human VCAM-1 incubated for 40 t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70KB6PubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50550224(CHEMBL4797755)copy SMILES
Affinity DataEC50:  6.70nMAssay Description:Agonist activity at alpha5beta1 in human K562 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50505782(CHEMBL4586928)copy SMILEScopy InChI
Affinity DataEC50:  9.90nMAssay Description:Agonist activity at alpha5beta1 integrin receptor in human K562 cells assessed as increase in fibronectin-induced cell adhesion pre-incubated for 30 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50505782(CHEMBL4586928)copy SMILEScopy InChI
Affinity DataEC50:  9.90nMAssay Description:Agonist activity at alpha5beta1 in human K562 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50505775(CHEMBL4442651)copy SMILEScopy InChI
Affinity DataEC50:  10nMAssay Description:Agonist activity at alpha4beta1 integrin receptor in human Jurkat E6.1 cells assessed as increase in VCAM1-induced cell adhesion pre-incubated for 30...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50021393(CHEMBL3289604)copy SMILEScopy InChI
Affinity DataEC50:  12nMAssay Description:Agonist activity at alpha5beta1 integrin in human K562 cells assessed as increase of fibronectin-mediated cell adhesion after 30 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75HWXPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50021393(CHEMBL3289604)copy SMILEScopy InChI
Affinity DataEC50:  12nMAssay Description:Agonist activity at alpha5beta1 in human K562 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50505772(CHEMBL4589062)copy SMILEScopy InChI
Affinity DataEC50:  13nMAssay Description:Agonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as increase in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50505772(CHEMBL4589062)copy SMILEScopy InChI
Affinity DataEC50:  13nMAssay Description:Agonist activity at alpha4beta1 integrin receptor in human Jurkat E6.1 cells assessed as increase in VCAM1-induced cell adhesion pre-incubated for 30...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50550223(CHEMBL4794300)copy SMILES
Affinity DataEC50:  45nMAssay Description:Agonist activity at alpha5beta1 in human K562 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50550225(CHEMBL4764510)copy SMILES
Affinity DataEC50:  49nMAssay Description:Agonist activity at alpha5beta1 in human K562 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-2/beta-1(Homo sapiens (Human))
Pliant Therapeutics

Curated by ChEMBL
LigandPNGBDBM50538004(CHEMBL4303254)copy SMILEScopy InChI
Affinity DataEC50:  130nMAssay Description:Inhibition of human alpha2 beta1 expressed in CHO cells assessed as reduction in cell adhesion to collagen type 1 incubated for 5 mins by DiOC6 dye b...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR302ZPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50505775(CHEMBL4442651)copy SMILEScopy InChI
Affinity DataEC50:  140nMAssay Description:Agonist activity at alpha5beta1 integrin receptor in human K562 cells assessed as increase in fibronectin-induced cell adhesion pre-incubated for 30 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-2/beta-1(Homo sapiens (Human))
Pliant Therapeutics

Curated by ChEMBL
LigandPNGBDBM50538003(CHEMBL4649149)copy SMILEScopy InChI
Affinity DataEC50:  160nMAssay Description:Inhibition of human alpha2 beta1 expressed in CHO cells assessed as reduction in cell adhesion to collagen type 1 incubated for 5 mins by DiOC6 dye b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2DR302ZPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50505770(CHEMBL4446073)copy SMILEScopy InChI
Affinity DataEC50:  255nMAssay Description:Agonist activity at alpha4beta1 integrin receptor in human Jurkat E6.1 cells assessed as increase in VCAM1-induced cell adhesion pre-incubated for 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50021395(CHEMBL3289606)copy SMILEScopy InChI
Affinity DataEC50:  365nMAssay Description:Agonist activity at alpha5beta1 integrin receptor in human K562 cells assessed as increase in fibronectin-induced cell adhesion pre-incubated for 30 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50021395(CHEMBL3289606)copy SMILEScopy InChI
Affinity DataEC50:  365nMAssay Description:Agonist activity at alpha5beta1 integrin in human K562 cells assessed as increase of fibronectin-mediated cell adhesion after 30 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75HWXPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50021395(CHEMBL3289606)copy SMILEScopy InChI
Affinity DataEC50:  365nMAssay Description:Agonist activity at alpha5beta1 in human K562 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50021394(CHEMBL3289605)copy SMILEScopy InChI
Affinity DataEC50:  763nMAssay Description:Agonist activity at alpha5beta1 in human K562 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50021394(CHEMBL3289605)copy SMILEScopy InChI
Affinity DataEC50:  763nMAssay Description:Agonist activity at alpha5beta1 integrin in human K562 cells assessed as increase of fibronectin-mediated cell adhesion after 30 mins by fluorescence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75HWXPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50505778(CHEMBL4447762)copy SMILEScopy InChI
Affinity DataEC50:  976nMAssay Description:Agonist activity at alpha4beta1 integrin receptor in human Jurkat E6.1 cells assessed as increase in VCAM1-induced cell adhesion pre-incubated for 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50505779(CHEMBL4461771)copy SMILEScopy InChI
Affinity DataEC50:  1.03E+3nMAssay Description:Agonist activity at alpha5beta1 in human K562 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50505779(CHEMBL4461771)copy SMILEScopy InChI
Affinity DataEC50:  1.03E+3nMAssay Description:Agonist activity at alpha5beta1 integrin receptor in human K562 cells assessed as increase in fibronectin-induced cell adhesion pre-incubated for 30 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50222360(Ac-Asp-Arg-Leu-Asp-Ser-OH | CHEMBL238484)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha5beta1 in human K562 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50505772(CHEMBL4589062)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha5beta1 in human K562 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50550228(CHEMBL4743438)copy SMILES
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha5beta1 in human K562 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibronectin...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50505782(CHEMBL4586928)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as increase in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50021393(CHEMBL3289604)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as increase in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50550228(CHEMBL4743438)copy SMILES
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as increase in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50021394(CHEMBL3289605)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as increase in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50021395(CHEMBL3289606)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as increase in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50550226(CHEMBL4782288)copy SMILES
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as increase in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50550224(CHEMBL4797755)copy SMILES
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as increase in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50505779(CHEMBL4461771)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as increase in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50550227(CHEMBL4755971)copy SMILES
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as increase in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50139204(3-[4-(3-Guanidino-benzoylamino)-phenylsulfanyl]-3-...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:CEMD9 cell adhesion via integrin alpha4-beta1 to VCAM1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0N4QPubMed
TargetIntegrin alpha-5/beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50139204(3-[4-(3-Guanidino-benzoylamino)-phenylsulfanyl]-3-...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:K562 cell adhesion via integrin alpha5-beta1 to fibrinogenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0N4QPubMed