Affinity DataIC50: 0.00130nMAssay Description:Inhibition of beta-adrenergic receptor in rat portal veinMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0450nMAssay Description:Inhibition of beta-adrenergic receptor in rat portal veinMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0510nMAssay Description:Inhibition of beta-adrenergic receptor in rat portal veinMore data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Rattus norvegicus)
Kissei Pharmaceutical Company Ltd.
Curated by ChEMBL
Kissei Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of spontaneous contractions in isolated rat uterusMore data for this Ligand-Target Pair
Affinity DataIC50: 0.440nMAssay Description:Inhibition of beta-adrenergic receptor in rat portal veinMore data for this Ligand-Target Pair
Affinity DataIC50: 0.460nMAssay Description:Inhibition of beta-adrenergic receptor in rat portal veinMore data for this Ligand-Target Pair
Affinity DataIC50: 0.780nMAssay Description:Inhibition of beta-adrenergic receptor in rat portal veinMore data for this Ligand-Target Pair
Affinity DataIC50: 0.900nMAssay Description:Beta-adrenergic agonistic activity in rat proximal colon in presence of phentolamine (10 uM), desmethylimipramine (0.5 uM) and hydrocortisone (30 uM)More data for this Ligand-Target Pair
Affinity DataIC50: 1.10nMAssay Description:Beta-adrenergic agonistic activity in rat proximal colon in presence of phentolamine (10 uM), desmethylimipramine (0.5 uM) and hydrocortisone (30 uM)More data for this Ligand-Target Pair
Affinity DataIC50: 1.5nMAssay Description:Inhibition of beta-adrenergic receptor in rat portal veinMore data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Rattus norvegicus)
Kissei Pharmaceutical Company Ltd.
Curated by ChEMBL
Kissei Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECAMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:The compound was evaluated for the inhibition of [125I]cyanopindolol binding to beta adrenergic receptor in rat reticulocyte membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 3.5nMAssay Description:Beta-adrenergic agonistic activity in rat proximal colon in presence of phentolamine (10 uM), desmethylimipramine (0.5 uM) and hydrocortisone (30 uM)More data for this Ligand-Target Pair
Affinity DataIC50: 5.30nMAssay Description:The compound was evaluated for the inhibition of [125I]cyanopindolol binding to beta adrenergic receptor in rat reticulocyte membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:The compound was evaluated for the inhibition of [125I]cyanopindolol binding to beta adrenergic receptor in rat reticulocyte membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of beta-adrenergic receptor in rat portal veinMore data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Rattus norvegicus)
Kissei Pharmaceutical Company Ltd.
Curated by ChEMBL
Kissei Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 9.10nMAssay Description:Inhibition of spontaneous contractions in isolated rat uterusMore data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Rattus norvegicus)
Kissei Pharmaceutical Company Ltd.
Curated by ChEMBL
Kissei Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 9.12nMAssay Description:Agonistic activity towards beta-2 adrenoceptor. Mean concentration required to produce 50% inhibition of uterine contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 19nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Beta-adrenergic agonistic activity in rat proximal colonMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:The compound was evaluated for the inhibition of [125I]cyanopindolol binding to beta adrenergic receptor in rat reticulocyte membrane.More data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Rattus norvegicus)
Kissei Pharmaceutical Company Ltd.
Curated by ChEMBL
Kissei Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 24.0nMAssay Description:Agonistic activity towards beta-2 adrenoceptor. Mean concentration required to produce 50% inhibition of uterine contractionMore data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Rattus norvegicus)
Kissei Pharmaceutical Company Ltd.
Curated by ChEMBL
Kissei Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Compound was evaluated for its binding affinity towards Beta-2 adrenergic receptor in rat soleus membrane by displacing (-)-isoproterenol (50 microM)More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of Rap1A-mediated geranylgeranylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair
Affinity DataIC50: 47nMAssay Description:Beta-adrenergic agonistic activity in rat proximal colonMore data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Rattus norvegicus)
Kissei Pharmaceutical Company Ltd.
Curated by ChEMBL
Kissei Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 61.7nMAssay Description:Agonistic activity towards beta-2 adrenoceptor. Mean concentration required to produce 50% inhibition of uterine contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Beta-adrenergic agonistic activity in rat proximal colonMore data for this Ligand-Target Pair
Affinity DataIC50: 97nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of H-Ras-mediated farnesylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair
Affinity DataIC50: 185nMAssay Description:Beta-adrenergic agonistic activity in rat uterus preincubated with phenoxybenzamine (12 uM) for 30 minMore data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Rattus norvegicus)
Kissei Pharmaceutical Company Ltd.
Curated by ChEMBL
Kissei Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 251nMAssay Description:Agonistic activity towards beta-2 adrenoceptor. Mean concentration required to produce 50% inhibition of uterine contractionMore data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Rattus norvegicus)
Kissei Pharmaceutical Company Ltd.
Curated by ChEMBL
Kissei Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 282nMAssay Description:Agonistic activity towards beta-2 adrenoceptor. Mean concentration required to produce 50% inhibition of uterine contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 319nMAssay Description:Beta-adrenergic agonistic activity in rat uterus preincubated with phenoxybenzamine (12 uM) for 30 minMore data for this Ligand-Target Pair
Affinity DataIC50: 325nMAssay Description:The compound was evaluated for the inhibition of [125I]cyanopindolol binding to beta adrenergic receptor in rat reticulocyte membrane.More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Beta-adrenergic agonistic activity in rat uterus preincubated with phenoxybenzamine (12 uM) for 30 minMore data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Beta-adrenergic agonistic activity in rat uterus preincubated with phenoxybenzamine (12 uM) for 30 minMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Tested for beta2-adrenergic blocking effect by measuring the ability to inhibit the relaxing effect of epinephrine on the isolated tracheal muscle of...More data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of Rap1A-mediated geranylgeranylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Rattus norvegicus)
Kissei Pharmaceutical Company Ltd.
Curated by ChEMBL
Kissei Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 520nMAssay Description:Inhibition of spontaneous contractions in isolated rat uterusMore data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of H-Ras-mediated farnesylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Rattus norvegicus)
Kissei Pharmaceutical Company Ltd.
Curated by ChEMBL
Kissei Pharmaceutical Company Ltd.
Curated by ChEMBL
Affinity DataIC50: 646nMAssay Description:Agonistic activity towards beta-2 adrenoceptor. Mean concentration required to produce 50% inhibition of uterine contractionMore data for this Ligand-Target Pair
Affinity DataIC50: 660nMAssay Description:Effect on synaptosomal uptake inhibition of Noradrenaline (NA)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [125I]pindolol from beta-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [125I]pindolol from beta-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory activity by measuring its ability to displace [125I]pindolol from beta-adrenergic receptor in rat brainMore data for this Ligand-Target Pair
