Compile Data Set for Download or QSAR
Found 39 of ic50 for UniProtKB: P25322
LigandPNGBDBM139540(US10189849, staurosporine | US10307427, Staurospor...)copy SMILEScopy InChI
Affinity DataIC50: 6.18nMMore data for this Ligand-Target Pair
In DepthDetails
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Human BioMolecular Research Institute

LigandPNGBDBM395789(US10308654, Example 17)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The test compound was dissolved in dimethyl sulfoxide and the solution was diluted to each concentration gradient with a buffer (50 mM HEPES, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70J5JUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Human BioMolecular Research Institute

LigandPNGBDBM395801(US10308654, Example 29)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The test compound was dissolved in dimethyl sulfoxide and the solution was diluted to each concentration gradient with a buffer (50 mM HEPES, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70J5JUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Human BioMolecular Research Institute

LigandPNGBDBM395784(US10308654, Example 12)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The test compound was dissolved in dimethyl sulfoxide and the solution was diluted to each concentration gradient with a buffer (50 mM HEPES, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70J5JUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Human BioMolecular Research Institute

LigandPNGBDBM395785(US10308654, Example 13)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The test compound was dissolved in dimethyl sulfoxide and the solution was diluted to each concentration gradient with a buffer (50 mM HEPES, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70J5JUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Human BioMolecular Research Institute

LigandPNGBDBM395786(US10308654, Example 14)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The test compound was dissolved in dimethyl sulfoxide and the solution was diluted to each concentration gradient with a buffer (50 mM HEPES, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70J5JUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Human BioMolecular Research Institute

LigandPNGBDBM395787(US10308654, Example 15)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The test compound was dissolved in dimethyl sulfoxide and the solution was diluted to each concentration gradient with a buffer (50 mM HEPES, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70J5JUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Human BioMolecular Research Institute

LigandPNGBDBM395788(US10308654, Example 16)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The test compound was dissolved in dimethyl sulfoxide and the solution was diluted to each concentration gradient with a buffer (50 mM HEPES, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70J5JUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Human BioMolecular Research Institute

LigandPNGBDBM395798(US10308654, Example 26)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The test compound was dissolved in dimethyl sulfoxide and the solution was diluted to each concentration gradient with a buffer (50 mM HEPES, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70J5JUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Human BioMolecular Research Institute

LigandPNGBDBM395790(US10308654, Example 18)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The test compound was dissolved in dimethyl sulfoxide and the solution was diluted to each concentration gradient with a buffer (50 mM HEPES, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70J5JUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Human BioMolecular Research Institute

LigandPNGBDBM395791(US10308654, Example 19)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The test compound was dissolved in dimethyl sulfoxide and the solution was diluted to each concentration gradient with a buffer (50 mM HEPES, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70J5JUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Human BioMolecular Research Institute

LigandPNGBDBM395792(US10308654, Example 20)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The test compound was dissolved in dimethyl sulfoxide and the solution was diluted to each concentration gradient with a buffer (50 mM HEPES, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70J5JUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Human BioMolecular Research Institute

LigandPNGBDBM395793(US10308654, Example 21)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The test compound was dissolved in dimethyl sulfoxide and the solution was diluted to each concentration gradient with a buffer (50 mM HEPES, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70J5JUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Human BioMolecular Research Institute

LigandPNGBDBM395799(US10308654, Example 27)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The test compound was dissolved in dimethyl sulfoxide and the solution was diluted to each concentration gradient with a buffer (50 mM HEPES, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70J5JUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Human BioMolecular Research Institute

LigandPNGBDBM395795(US10308654, Example 23)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The test compound was dissolved in dimethyl sulfoxide and the solution was diluted to each concentration gradient with a buffer (50 mM HEPES, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70J5JUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Human BioMolecular Research Institute

LigandPNGBDBM395796(US10308654, Example 24)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The test compound was dissolved in dimethyl sulfoxide and the solution was diluted to each concentration gradient with a buffer (50 mM HEPES, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70J5JUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Human BioMolecular Research Institute

LigandPNGBDBM395797(US10308654, Example 25)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:The test compound was dissolved in dimethyl sulfoxide and the solution was diluted to each concentration gradient with a buffer (50 mM HEPES, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70J5JUS Patent
LigandPNGBDBM622518(US20230312583, Compound I-14)copy SMILES
Affinity DataIC50: 23.9nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Human BioMolecular Research Institute

LigandPNGBDBM395800(US10308654, Example 28)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:The test compound was dissolved in dimethyl sulfoxide and the solution was diluted to each concentration gradient with a buffer (50 mM HEPES, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70J5JUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
Human BioMolecular Research Institute

LigandPNGBDBM395794(US10308654, Example 22)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:The test compound was dissolved in dimethyl sulfoxide and the solution was diluted to each concentration gradient with a buffer (50 mM HEPES, 10 mM M...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2H70J5JUS Patent
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Mus musculus (mouse))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6866(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b ...)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 10 uM ATP/[gamma-33P]ATP in a streptavidin coated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7KNXPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Mus musculus (mouse))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6870(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3f ...)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 10 uM ATP/[gamma-33P]ATP in a streptavidin coated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7KNXPubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Mus musculus (mouse))
Johnson & Johnson Pharmaceutical

LigandPNGBDBM6867(1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3c ...)copy SMILEScopy InChI
Affinity DataIC50: 190nMAssay Description:The enzyme was assayed with a biotinylated peptide substrate and test compounds in the presence of 10 uM ATP/[gamma-33P]ATP in a streptavidin coated...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7KNXPubMed