Compile Data Set for Download or QSAR
Found 47 of ec50 for UniProtKB: P28472
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50065229(4-Ethyl-6,7-dimethoxy-9H-beta-carboline-3-carboxyl...)copy SMILEScopy InChI
Affinity DataEC50:  10nMAssay Description:Binding affinity to human alpha3beta3gamma2 GABA receptor expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB536XPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50259825(CHEMBL4089504)copy SMILEScopy InChI
Affinity DataEC50:  11nMAssay Description:Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ92T0PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50259822(CHEMBL514974)copy SMILEScopy InChI
Affinity DataEC50:  29nMAssay Description:Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ92T0PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Homo sapiens (Human))
Sage Therapeutics, Inc. 215 First Street, Cambridge, Massachusetts 02142, United States.

Curated by ChEMBL
LigandPNGBDBM50191342(3alpha-hydroxy-5alpha-pregnan-20-one | CHEMBL20753...)copy SMILEScopy InChI
Affinity DataEC50:  76nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332374(9-Amino-2-cyclobutyl-5-(pyrimidin-2-yl)-2,3-dihydr...)copy SMILEScopy InChI
Affinity DataEC50:  77nMAssay Description:Binding affinity to human alpha3beta3gamma2 GABA receptor expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB536XPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Homo sapiens (Human))
Sage Therapeutics, Inc. 215 First Street, Cambridge, Massachusetts 02142, United States.

Curated by ChEMBL
LigandPNGBDBM50258254(CHEMBL4073780)copy SMILEScopy InChI
Affinity DataEC50:  110nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5K4WPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000766(CHEMBL12 | DIAZEPAM | US9271961, Diazepam)copy SMILEScopy InChI
Affinity DataEC50:  131nMAssay Description:Binding affinity to human alpha3beta3gamma2 GABA receptor expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM25883(ethyl 12-ethynyl-9-phenyl-2,4,8-triazatricyclo[8.4...)copy SMILEScopy InChI
Affinity DataEC50:  146nMAssay Description:Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ92T0PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332375(4-Amino-8-(5-(azetidine-1-carbonyl)pyridin-3-yl)-N...)copy SMILEScopy InChI
Affinity DataEC50:  174nMAssay Description:Binding affinity to human alpha3beta3gamma2 GABA receptor expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB536XPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Homo sapiens (Human))
Sage Therapeutics, Inc. 215 First Street, Cambridge, Massachusetts 02142, United States.

Curated by ChEMBL
LigandPNGBDBM50258255(CHEMBL4062424)copy SMILEScopy InChI
Affinity DataEC50:  192nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5K4WPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50259814(CHEMBL4062225)copy SMILEScopy InChI
Affinity DataEC50:  205nMAssay Description:Modulation of recombinant human GABA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as change in GABA-induced current at -80 mV holdin...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ92T0PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Homo sapiens (Human))
Sage Therapeutics, Inc. 215 First Street, Cambridge, Massachusetts 02142, United States.

Curated by ChEMBL
LigandPNGBDBM50258256(CHEMBL3427532)copy SMILEScopy InChI
Affinity DataEC50:  240nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5K4WPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Homo sapiens (Human))
Sage Therapeutics, Inc. 215 First Street, Cambridge, Massachusetts 02142, United States.

Curated by ChEMBL
LigandPNGBDBM50258216(CHEMBL4105630)copy SMILEScopy InChI
Affinity DataEC50:  299nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5K4WPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50259815(CHEMBL4090978)copy SMILEScopy InChI
Affinity DataEC50:  321nMAssay Description:Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ92T0PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50332376(4-Amino-N-propyl-8-(pyrimidin-2-yl)cinnoline-3-car...)copy SMILEScopy InChI
Affinity DataEC50:  379nMAssay Description:Binding affinity to human alpha3beta3gamma2 GABA receptor expressed in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB536XPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50259821(CHEMBL2332214)copy SMILEScopy InChI
Affinity DataEC50:  470nMAssay Description:Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ92T0PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Homo sapiens (Human))
Sage Therapeutics, Inc. 215 First Street, Cambridge, Massachusetts 02142, United States.

Curated by ChEMBL
LigandPNGBDBM50258248(CHEMBL4084134)copy SMILEScopy InChI
Affinity DataEC50:  577nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5K4WPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Homo sapiens (Human))
Sage Therapeutics, Inc. 215 First Street, Cambridge, Massachusetts 02142, United States.

Curated by ChEMBL
LigandPNGBDBM50258253(CHEMBL4085062)copy SMILEScopy InChI
Affinity DataEC50:  744nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5K4WPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50259824(CHEMBL475022)copy SMILEScopy InChI
Affinity DataEC50:  844nMAssay Description:Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ92T0PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50259814(CHEMBL4062225)copy SMILEScopy InChI
Affinity DataEC50:  937nMAssay Description:Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ92T0PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM86521(CAS_5719 | NSC_5719 | Zaleplon)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+3nMAssay Description:Modulation of human GABAA alpha3beta3gamma2 expressed in xenopus oocytes assessed as potentiation of GABA-evoked chloride currentsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61GZPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50259824(CHEMBL475022)copy SMILEScopy InChI
Affinity DataEC50:  1.17E+3nMAssay Description:Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ92T0PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Homo sapiens (Human))
Sage Therapeutics, Inc. 215 First Street, Cambridge, Massachusetts 02142, United States.

Curated by ChEMBL
LigandPNGBDBM50258217(CHEMBL3427530)copy SMILEScopy InChI
Affinity DataEC50:  1.24E+3nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5K4WPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Homo sapiens (Human))
Sage Therapeutics, Inc. 215 First Street, Cambridge, Massachusetts 02142, United States.

Curated by ChEMBL
LigandPNGBDBM50258252(CHEMBL4073679)copy SMILEScopy InChI
Affinity DataEC50:  1.36E+3nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5K4WPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)copy SMILEScopy InChI
Affinity DataEC50:  1.50E+3nMAssay Description:Antagonistic potency against human Gamma-aminobutyric-acid A receptor alpha2-beta3-gamma2 expressed in Xenopus oocytes at 1 mMMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Homo sapiens (Human))
Sage Therapeutics, Inc. 215 First Street, Cambridge, Massachusetts 02142, United States.

Curated by ChEMBL
LigandPNGBDBM50258229(CHEMBL4103751)copy SMILEScopy InChI
Affinity DataEC50:  1.60E+3nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5K4WPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Homo sapiens (Human))
Sage Therapeutics, Inc. 215 First Street, Cambridge, Massachusetts 02142, United States.

Curated by ChEMBL
LigandPNGBDBM50258249(CHEMBL4080678)copy SMILEScopy InChI
Affinity DataEC50:  2.01E+3nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5K4WPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Homo sapiens (Human))
Sage Therapeutics, Inc. 215 First Street, Cambridge, Massachusetts 02142, United States.

Curated by ChEMBL
LigandPNGBDBM50258243(CHEMBL4081622)copy SMILEScopy InChI
Affinity DataEC50:  2.05E+3nMAssay Description:Positive allosteric modulation of GABAA receptor alpha4beta3delta (unknown origin) expressed in CHO cells assessed as potentiation of GABA-mediated i...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ZK5K4WPubMed
LigandPNGBDBM50551942(CHEMBL4748423)copy SMILES
Affinity DataEC50:  2.90E+3nMAssay Description:Positive allosteric modulation of GABAA alpha1beta3 in HEK cell plasma membrane assessed as increase in [3H]muscimol binding measured after 10 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78JT8PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50259816(CHEMBL4063081)copy SMILEScopy InChI
Affinity DataEC50:  3.02E+3nMAssay Description:Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ92T0PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50259820(CHEMBL4098713)copy SMILEScopy InChI
Affinity DataEC50:  5.15E+3nMAssay Description:Binding affinity to human GABAA alpha3beta3gamma2 receptor expressed in HEK293 cells assessed as GABA-induced membrane potential change preincubated ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ92T0PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50087272(CHEMBL34155 | P4S | Piperidine-4-sulfonic acid | P...)copy SMILEScopy InChI
Affinity DataEC50:  2.00E+4nMAssay Description:Effective agonist dose for human Gamma-aminobutyric-acid A receptor alpha4-beta3-gamma2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DDQPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50032955(1,2,3,6-Tetrahydro-pyridine-4-carboxylic acid | 1,...)copy SMILEScopy InChI
Affinity DataEC50:  2.00E+4nMAssay Description:Effective agonist dose for human Gamma-aminobutyric-acid A receptor alpha4-beta3-gamma2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DDQPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50452383(CHEMBL4218339)copy SMILEScopy InChI
Affinity DataEC50: >2.40E+4nMAssay Description:Displacement of [3H]-flumazenil from human GABA-A receptor alpha3beta3gamma2 expressed in HEK293 cells by electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27D2XQ8PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM24183(4-amino-n-[2,3-3H]butyric acid | 4-aminobutanoic a...)copy SMILEScopy InChI
Affinity DataEC50:  2.80E+4nMAssay Description:Effective agonist dose for human Gamma-aminobutyric-acid A receptor alpha6-beta3-gamma2More data for this Ligand-Target Pair
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50032955(1,2,3,6-Tetrahydro-pyridine-4-carboxylic acid | 1,...)copy SMILEScopy InChI
Affinity DataEC50:  5.50E+4nMAssay Description:Antagonistic potency against human Gamma-aminobutyric-acid A receptor alpha2-beta3-gamma2 expressed in Xenopus oocytes at 1 mMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DDQPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50087272(CHEMBL34155 | P4S | Piperidine-4-sulfonic acid | P...)copy SMILEScopy InChI
Affinity DataEC50:  6.50E+4nMAssay Description:Agonist activity on human Gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DDQPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50100944(CHEMBL291079 | Piperidin-4-yl-phosphinic acid)copy SMILEScopy InChI
Affinity DataEC50:  1.40E+5nMAssay Description:Agonist activity on human Gamma-aminobutyric-acid A receptor alpha2-beta3-gamma2 expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DDQPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50000106(4-CARBOXYPIPERIDINE | CHEMBL279998 | Piperidine-4-...)copy SMILEScopy InChI
Affinity DataEC50:  1.60E+5nMAssay Description:Effective agonist dose for human Gamma-aminobutyric-acid A receptor alpha6-beta3-gamma2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DDQPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50100944(CHEMBL291079 | Piperidin-4-yl-phosphinic acid)copy SMILEScopy InChI
Affinity DataEC50:  1.60E+5nMAssay Description:Agonist activity on human Gamma-aminobutyric-acid A receptor alpha2-beta3-gamma2 expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DDQPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50100946(CHEMBL290961 | Piperidine-4-selenic acid | piperid...)copy SMILEScopy InChI
Affinity DataEC50:  1.80E+5nMAssay Description:Effective agonist dose for human Gamma-aminobutyric-acid A receptor alpha1-beta3-gamma2 expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DDQPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50100946(CHEMBL290961 | Piperidine-4-selenic acid | piperid...)copy SMILEScopy InChI
Affinity DataEC50:  2.40E+5nMAssay Description:Effective agonist dose for human Gamma-aminobutyric-acid A receptor alpha1-beta3-gamma2 expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DDQPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM85712(1H-imidazol-4-ylacetic acid | CAS_645-65-8 | CHEMB...)copy SMILEScopy InChI
Affinity DataEC50:  3.00E+5nMAssay Description:Antagonistic potency against human Gamma-aminobutyric-acid A receptor alpha1-beta3-gamma2 expressed in Xenopus oocytes at 1 mMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DDQPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50000106(4-CARBOXYPIPERIDINE | CHEMBL279998 | Piperidine-4-...)copy SMILEScopy InChI
Affinity DataEC50:  3.70E+5nMAssay Description:Effective agonist dose for human Gamma-aminobutyric-acid A receptor alpha6-beta3-gamma2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DDQPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM85712(1H-imidazol-4-ylacetic acid | CAS_645-65-8 | CHEMB...)copy SMILEScopy InChI
Affinity DataEC50:  4.60E+5nMAssay Description:Antagonistic potency against human Gamma-aminobutyric-acid A receptor alpha2-beta3-gamma2 expressed in Xenopus oocytes at 1 mMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DDQPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50100943(3-Amino-propane-1-selenic acid | CHEMBL41065)copy SMILEScopy InChI
Affinity DataEC50:  3.00E+6nMAssay Description:Agonist activity on human Gamma-aminobutyric-acid A receptor alpha3-beta3-gamma2 expressed in Xenopus oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DDQPubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50100943(3-Amino-propane-1-selenic acid | CHEMBL41065)copy SMILEScopy InChI
Affinity DataEC50:  4.90E+6nMAssay Description:Effective agonist dose for human Gamma-aminobutyric-acid A receptor alpha6-beta3-gamma2More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24J0DDQPubMed