Compile Data Set for Download or QSAR
Found 524 of ic50 for UniProtKB: P30729
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.280nMAssay Description:Ability to inhibit [3H]haloperidol binding to dopamine receptor in rat striatal homogenateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KW5J7HPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50020220(3-Dipropylamino-chroman-8-ol | CHEMBL38428)copy SMILEScopy InChI
Affinity DataIC50: 0.320nMAssay Description:In vitro affinity to dopamine receptor using [3H]NPAD as radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2KD2140PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50334150(1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of [3H]haloperidol binding to dopamine receptors in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TB193ZPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50334150(1-(1-(4,4-bis(4-fluorophenyl)butyl)piperidin-4-yl)...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Inhibition of [3H]haloperidol binding to dopamine receptors in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TB193ZPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.400nMAssay Description:Binding affinity against dopamine receptor in rat striatal membrane using [3H]haloperidolMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2319TVFPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50225369(CHEMBL295712)copy SMILEScopy InChI
Affinity DataIC50: 0.610nMAssay Description:Inhibition of [3H]haloperidol binding to dopamine receptors in rat striatal membranes.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2TB193ZPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50007518((S)-3-chloro-5-ethyl-N-((1-ethylpyrrolidin-2-yl)me...)copy SMILEScopy InChI
Affinity DataIC50: 0.920nMAssay Description:Antidopamine activity in vitro by ability to displace [3H]spiperone from rat brain striatal preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZCHPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:Inhibition of [3H]apomorphine binding to calf caudate membrane preparation (p4)More data for this Ligand-Target Pair
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)copy SMILEScopy InChI
Affinity DataIC50: 1.10nMAssay Description:Dopaminergic activity assessed in vitro for displacement of [3H]apomorphine from specific binding sites on rat striatal membranesMore data for this Ligand-Target Pair
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)copy SMILEScopy InChI
Affinity DataIC50: 1.40nMAssay Description:Inhibitory concentration for half-maximal displacement of 1.0 nM [3H]ADTN specific binding from rat striatal membranes using 10E-5 sulpirideMore data for this Ligand-Target Pair
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50225774(CHEMBL161122)copy SMILEScopy InChI
Affinity DataIC50: 1.5nMAssay Description:Antidopamine activity in vitro by ability to displace [3H]spiperone from rat brain striatal preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZCHPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50017543((6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Inhibition of [3H]apomorphine binding to dopamine receptor of rat corpus striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5Q18PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM81195((+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaph...)copy SMILEScopy InChI
Affinity DataIC50: 1.70nMAssay Description:Inhibitory concentration for half-maximal displacement of 1.0 nM [3H]ADTN specific binding from rat striatal membranes using 10E-5 sulpirideMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J67K44PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Inhibitory concentration half-maximal displacement of 1.0 nM [3H]NPA specific binding from rat striatal membranes using 10e-5 (+/-)ADTNMore data for this Ligand-Target Pair
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026051(3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-h...)copy SMILEScopy InChI
Affinity DataIC50: 1.80nMAssay Description:Antidopamine activity in vitro by ability to displace [3H]spiperone from rat brain striatal preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZCHPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50225247(CHEMBL44558)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Dopaminergic activity assessed in vitro for displacement of [3H]apomorphine from specific binding sites on rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NT8PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50224790(CHEMBL333794)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:In vitro affinity for dopamine receptor by displacement of [3H]- apomorphine in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BG2R63PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibitory concentration half-maximal displacement of 1.0 nM [3H]NPA specific binding from rat striatal membranes using 10e-5 (+/-)ADTNMore data for this Ligand-Target Pair
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50366495((+)butaclamol | CHEMBL1255588)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Concentration inhibiting the specific binding of [3H]spiroperidol by 50%More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6MMXPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50008735((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...)copy SMILEScopy InChI
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]spiperone binding to dopamine receptor from rat corpus striatal membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73GXDPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM55121(3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...)copy SMILEScopy InChI
Affinity DataIC50: 2.10nMAssay Description:Inhibitory concentration for half-maximal displacement of 1.0 nM [3H]ADTN specific binding from rat striatal membranes using 10E-5 sulpirideMore data for this Ligand-Target Pair
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50224791(CHEMBL333795 | RU-29717)copy SMILEScopy InChI
Affinity DataIC50: 2.20nMAssay Description:In vitro affinity for dopamine receptor by displacement of [3H]- apomorphine in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BG2R63PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Effect on synaptosomal uptake inhibition of Dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3MR6PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50225894(CHEMBL63789)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Affinity for Dopamine receptors in the rat striatum using [3H]spiroperidol displacement.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W66NZFPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026044(3-Bromo-5-ethyl-N-(1-ethyl-pyrrolidin-2-ylmethyl)-...)copy SMILEScopy InChI
Affinity DataIC50: 2.30nMAssay Description:Antidopamine activity in vitro by ability to displace [3H]spiperone from rat brain striatal preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZCHPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026553((+)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibitory activity against [3H]NPA binding (0.45) to dopamine receptor in striata of female wistar ratsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H4KPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026553((+)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibitory activity against [3H]NPA binding (0.45) to dopamine receptor in striata of female wistar ratsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H4KPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50007422((+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...)copy SMILEScopy InChI
Affinity DataIC50: 2.5nMAssay Description:Inhibition of [3H]apomorphine binding to calf caudate membrane preparation (p4)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QV3PQKPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50225762(CHEMBL161973)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:Antidopamine activity in vitro by ability to displace [3H]spiperone from rat brain striatal preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZCHPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50001955((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...)copy SMILEScopy InChI
Affinity DataIC50: 2.60nMAssay Description:In vitro affinity to dopamine receptor using [3H]NPAD as radioligand in rat striatal membranesMore data for this Ligand-Target Pair
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50327157((R)-methyl 2-(3,4-dichlorophenyl)-2-((R)-piperidin...)copy SMILEScopy InChI
Affinity DataIC50: 2.70nMAssay Description:Potency of inhibiting 10 pM [125I]-RTI-55 binding to dopamine receptor in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43SJ8PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026958((cis) 2-{4-[3-(3,4-Dichloro-phenyl)-indan-1-yl]-pi...)copy SMILEScopy InChI
Affinity DataIC50: 2.80nMAssay Description:Effect on synaptosomal uptake inhibition of Dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3MR6PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM22872(1-(3-chloro-5,6-dihydrobenzo[b][1]benzothiepin-5-y...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Ability to displace [3H]haloperidol from rat striatal membranes, in order to measure its intrinsic affinity for the dopamine (DA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3MR6PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM79172(2-[4-[(3Z)-3-[2-(trifluoromethyl)-9-thioxanthenyli...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Ability to displace [3H]haloperidol from rat striatal membranes, in order to measure its intrinsic affinity for the dopamine (DA) receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3MR6PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50225771(CHEMBL350287)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Antidopamine activity in vitro by ability to displace [3H]spiperone from rat brain striatal preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZCHPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM81195((+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaph...)copy SMILEScopy InChI
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration half-maximal displacement of 1.0 nM [3H]NPA specific binding from rat striatal membranes using 10e-5 (+/-)ADTNMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2J67K44PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50017543((6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:In vitro affinity for dopamine receptor by displacement of [3H]- apomorphine in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BG2R63PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM81195((+/-)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaph...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Evaluated for the inhibition of binding of [3H]DA (dopamine) to dopamine receptor in rat brain homogenateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RR21GGPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50017543((6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Dopaminergic activity assessed in vitro for displacement of [3H]apomorphine from specific binding sites on rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NT8PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50225267(CHEMBL48264)copy SMILEScopy InChI
Affinity DataIC50: 3.20nMAssay Description:Concentration inhibiting the specific binding of [3H]naloxone by 50% in the absence of NaClMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6MMXPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50225241(CHEMBL42242)copy SMILEScopy InChI
Affinity DataIC50: 3.30nMAssay Description:Dopaminergic activity assessed in vitro for displacement of [3H]apomorphine from specific binding sites on rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SJ1NT8PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026553((+)-6-Dipropylamino-5,6,7,8-tetrahydro-naphthalene...)copy SMILEScopy InChI
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against [3H]NPA binding (0.45) to dopamine receptors in striata of female wistar ratsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JW8H4KPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50017543((6aR,9R,10aR)-9-Methylsulfanylmethyl-7-propyl-4,6,...)copy SMILEScopy InChI
Affinity DataIC50: 4.10nMAssay Description:Inhibition of [3H]dopamine binding to dopamine receptor of rat corpus striatumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29G5Q18PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50021224((+) (trans) 1-[3-(3,4-Dichloro-phenyl)-indan-1-yl]...)copy SMILEScopy InChI
Affinity DataIC50: 4.40nMAssay Description:Effect on synaptosomal uptake inhibition of Dopamine receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JH3MR6PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50026059(3,5-Dichloro-N-(1-ethyl-pyrrolidin-2-ylmethyl)-2-h...)copy SMILEScopy InChI
Affinity DataIC50: 4.70nMAssay Description:Antidopamine activity in vitro by ability to displace [3H]spiperone from rat brain striatal preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZCHPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50225266(CHEMBL555325)copy SMILEScopy InChI
Affinity DataIC50: 4.80nMAssay Description:Concentration inhibiting the specific binding of [3H]naloxone by 50% in the absence of NaClMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6MMXPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50007422((+)-6-Propyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]q...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of [3H]apomorphine binding to calf caudate membrane preparation (p4)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QV3PQKPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50225770(CHEMBL345223)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Antidopamine activity in vitro by ability to displace [3H]spiperone from rat brain striatal preparations.More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2SF2ZCHPubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50327157((R)-methyl 2-(3,4-dichlorophenyl)-2-((R)-piperidin...)copy SMILEScopy InChI
Affinity DataIC50: 5.30nMAssay Description:Potency of inhibiting 10 pM [125I]-RTI-55 binding to dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T43SJ8PubMed
TargetD(1A)/D(1B)/D(2)/D(3)/D(4) dopamine receptor(Rattus norvegicus (rat))
TBA

Curated by ChEMBL
LigandPNGBDBM50000092((-)-(etorphine) | (-)-morphine | (1S,5R,13R,14S)-1...)copy SMILEScopy InChI
Affinity DataIC50: 5.40nMAssay Description:Concentration inhibiting the specific binding of [3H]naloxone by 50% in the absence of NaClMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24T6MMXPubMed
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