Compile Data Set for Download or QSAR
Found 147 of ic50 for UniProtKB: P35222
TargetCatenin beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50408050(CHEMBL5282944)copy SMILEScopy InChI
Affinity DataIC50: 4.20nMAssay Description:Affinity for CCK2 receptor assessed by inhibition of pentagastrin-stimulated acid secretion in perfused rat stomachMore data for this Ligand-Target Pair
In DepthDetails
TargetCatenin beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM396286(US10314832, Compound 2)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M047TCUS Patent
TargetCatenin beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM396284(US10314832, Compound 1)copy SMILEScopy InChI
Affinity DataIC50: 28.5nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M047TCUS Patent
TargetCatenin beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM396287(US10314832, Compound 3)copy SMILEScopy InChI
Affinity DataIC50: 38.5nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M047TCUS Patent
TargetCatenin beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM396292(US10314832, Compound 8)copy SMILEScopy InChI
Affinity DataIC50: 83nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M047TCUS Patent
TargetCatenin beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM396291(US10314832, Compound 7)copy SMILEScopy InChI
Affinity DataIC50: 183nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M047TCUS Patent
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148380(US9682961, 29)copy SMILES
Affinity DataIC50: 300nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM143712(US9682961, 1)copy SMILES
Affinity DataIC50: 300nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148359(US9682961, 13)copy SMILES
Affinity DataIC50: 300nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1/Transcription factor 7-like 2(Homo sapiens (Human))
University of Michigan

Curated by ChEMBL
LigandPNGBDBM40314(3-(4-Chloro-phenyl)-1,6-dimethyl-1H-pyrimido[5,4-e...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Inhibition of human TCF4/ flag epitope-tagged beta-catenin (unknown origin) interaction transfected in human HCT116 cells after 24 hrs by beta-galact...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RV0Q4JPubMed
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148402(US9682961, 44)copy SMILES
Affinity DataIC50: 300nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148401(US9682961, 43)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148400(US9682961, 42)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148391(US9682961, 37)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148390(US9682961, 36)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148385(US9682961, 31)copy SMILES
Affinity DataIC50: 300nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50014132(CHEMBL2323032)copy SMILEScopy InChI
Affinity DataIC50: 500nMAssay Description:Affinity for CCK2 receptor assessed by inhibition of pentagastrin-stimulated acid secretion in perfused rat stomachMore data for this Ligand-Target Pair
In DepthDetails
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148399(US9682961, 41)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148360(US9682961, 14)copy SMILES
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148364(US9682961, 17)copy SMILES
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148384(US9682961, 30)copy SMILES
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148365(US9682961, 18)copy SMILES
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148378(US9682961, 27)copy SMILES
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148396(US9682961, 39)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148393(US9682961, 38)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148386(US9682961, 32)copy SMILES
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148389(US9682961, 35)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148403(US9682961, 45)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148404(US9682961, 46)copy SMILEScopy InChI
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148368(US9682961, 20)copy SMILES
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148376(US9682961, 25)copy SMILES
Affinity DataIC50: 650nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM396288(US10314832, Compound 11 | US10314832, Compound 4)copy SMILEScopy InChI
Affinity DataIC50: 805nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M047TCUS Patent
TargetCatenin beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM396289(US10314832, Compound 5)copy SMILEScopy InChI
Affinity DataIC50: 1.27E+3nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M047TCUS Patent
TargetCatenin beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM396298(US10314832, Compound 15)copy SMILEScopy InChI
Affinity DataIC50: 1.39E+3nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M047TCUS Patent
TargetCatenin beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50509812(CHEMBL4548532)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP85G5PubMed
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148366(US9682961, 19)copy SMILES
Affinity DataIC50: 2.00E+3nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148397(US9682961, 40)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+3nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50589223(CHEMBL5185515)copy SMILES
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ72Q3PubMed
TargetCatenin beta-1/Protein Wnt-3a(Homo sapiens (Human))
CARNA BIOSCIENCES, INC.; NATIONAL CANCER CENTER

US Patent
LigandPNGBDBM148377(US9682961, 26)copy SMILES
Affinity DataIC50: 2.00E+3nMAssay Description:Using ONE-Glo Luciferase Assay System (Promega Corporation, No. E6110), the luciferase activity of the cells in the wells was measured by a microplat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K935P5US Patent
TargetCatenin beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM396290(US10314832, Compound 6)copy SMILEScopy InChI
Affinity DataIC50: 2.10E+3nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M047TCUS Patent
TargetCatenin beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50509813(CHEMBL4451478)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP85G5PubMed
TargetCatenin beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM396299(US10314832, Compound 16)copy SMILEScopy InChI
Affinity DataIC50: 2.57E+3nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M047TCUS Patent
TargetCatenin beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM396302(US10314832, Compound 19)copy SMILEScopy InChI
Affinity DataIC50: 3.90E+3nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M047TCUS Patent
TargetCatenin beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50436055(CHEMBL2397076)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of beta-catenin-mediated transcriptional activity in Wnt3a-stimulated human HeLa cells after 24 hrs by Dual-Glo luciferase reporter gene a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP046ZPubMed
TargetCatenin beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50436054(CHEMBL2397077)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of beta-catenin-mediated transcriptional activity in Wnt3a-stimulated human HeLa cells after 24 hrs by Dual-Glo luciferase reporter gene a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BP046ZPubMed
TargetCatenin beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50509810(CHEMBL4464142)copy SMILEScopy InChI
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP85G5PubMed
TargetCatenin beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM396301(US10314832, Compound 18)copy SMILEScopy InChI
Affinity DataIC50: 6.00E+3nMAssay Description:Compounds that enhance the Wnt activity, or Activators, were assayed as follows. Reporter cell lines were generated by stably transducing cells of ca...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M047TCUS Patent
TargetCatenin beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50014148(CHEMBL3260853)copy SMILEScopy InChI
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of human wild-type beta-catenin (residues 138-686)/C-terminally fluorescein labeled human wild-type Tcf4 (residues 7-51) interaction after...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G44S28PubMed
TargetCatenin beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50509801(CHEMBL4464433)copy SMILEScopy InChI
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP85G5PubMed
TargetCatenin beta-1(Homo sapiens (Human))TBA
LigandPNGBDBM50509781(CHEMBL4450852)copy SMILEScopy InChI
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of C-terminal fluorescein-labeled human TCF4 (7 to 51 residues) binding to wild-type C-terminal His6-tagged beta-catenin (138 to 781 resid...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP85G5PubMed
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