Compile Data Set for Download or QSAR
Found 6 of ic50 for UniProtKB: P70579
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50372868(CHEMBL404886)copy SMILEScopy InChI
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of [3H]-L-AP4 from rat mGluR8More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VD7096PubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50280368(CHEMBL4176971)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat mGlu8 expressed in HEK cells co-expressing Galpha15 assessed as reduction in L-AP4-induced intracellular calcium flux pret...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CG2PubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50280374(CHEMBL4174742)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu8 receptor expressed in HEK cells co-expressing Galphai5 assessed as decrease in glutamate-induced thallium...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2B85BN1PubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50503456(CHEMBL4435396)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu8 receptor expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium flux p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125WWXPubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50503462(CHEMBL4527834)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Negative allosteric modulation of rat mGlu8 receptor expressed in HEK cells harboring GIRK assessed as reduction in glutamate-induced thallium flux p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2125WWXPubMed
TargetMetabotropic glutamate receptor 8(Rattus norvegicus (Rat))
F. Hoffmann-La Roche Ltd

Curated by ChEMBL
LigandPNGBDBM50280371(CHEMBL4160779)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro inhibitory activity against angiotensin I converting enzyme of rats.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25X2CG2PubMed