Compile Data Set for Download or QSAR
Found 23 of ec50 for UniProtKB: P05106
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of New Mexico School of Medicine

Curated by ChEMBL
LigandPNGBDBM50332898(2-(benzo[d]thiazol-2-yl)-5-((4-chlorophenylthio)me...)copy SMILEScopy InChI
Affinity DataEC50:  1.30nMAssay Description:Inhibition of human alphaVbeta3 receptor expressed in african green monkey Vero E6 cells assessed as inhibition of SNV infection in cells by immunofl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PB4PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of New Mexico School of Medicine

Curated by ChEMBL
LigandPNGBDBM50332896(CHEMBL1630982 | rac-N-(benzo[d][1,3]dioxol-5-ylmet...)copy SMILEScopy InChI
Affinity DataEC50:  1.60nMAssay Description:Inhibition of human alphaVbeta3 receptor expressed in african green monkey Vero E6 cells assessed as inhibition of SNV infection in cells by immunofl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PB4PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of New Mexico School of Medicine

Curated by ChEMBL
LigandPNGBDBM50332897(CHEMBL1631618 | rac-2-(benzo[c][1,2,5]thiadiazole-...)copy SMILEScopy InChI
Affinity DataEC50:  2.5nMAssay Description:Inhibition of human alphaVbeta3 receptor expressed in african green monkey Vero E6 cells assessed as inhibition of SNV infection in cells by immunofl...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2Z60PB4PubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of New Mexico School of Medicine

Curated by ChEMBL
LigandPNGBDBM50021394(CHEMBL3289605)copy SMILEScopy InChI
Affinity DataEC50:  11nMAssay Description:Agonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibron...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of New Mexico School of Medicine

Curated by ChEMBL
LigandPNGBDBM50021394(CHEMBL3289605)copy SMILEScopy InChI
Affinity DataEC50:  11nMAssay Description:Agonist activity at alphavbeta3 integrin in human SK-MEL-24 cells assessed as increase of fibronectin-mediated cell adhesion after 30 mins by fluores...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75HWXPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of New Mexico School of Medicine

Curated by ChEMBL
LigandPNGBDBM50505774(CHEMBL4469125)copy SMILEScopy InChI
Affinity DataEC50:  30nMAssay Description:Agonist activity at alphaVbeta3 integrin receptor in human SK-MEL-24 cells assessed as increase in fibronectin-induced cell adhesion pre-incubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of New Mexico School of Medicine

Curated by ChEMBL
LigandPNGBDBM50021393(CHEMBL3289604)copy SMILEScopy InChI
Affinity DataEC50:  55nMAssay Description:Agonist activity at alphavbeta3 integrin in human SK-MEL-24 cells assessed as increase of fibronectin-mediated cell adhesion after 30 mins by fluores...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75HWXPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of New Mexico School of Medicine

Curated by ChEMBL
LigandPNGBDBM50021393(CHEMBL3289604)copy SMILEScopy InChI
Affinity DataEC50:  55nMAssay Description:Agonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibron...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of New Mexico School of Medicine

Curated by ChEMBL
LigandPNGBDBM50505770(CHEMBL4446073)copy SMILEScopy InChI
Affinity DataEC50:  76nMAssay Description:Agonist activity at alphaVbeta3 integrin receptor in human SK-MEL-24 cells assessed as increase in fibronectin-induced cell adhesion pre-incubated fo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of New Mexico School of Medicine

Curated by ChEMBL
LigandPNGBDBM50505776(CHEMBL4454796)copy SMILEScopy InChI
Affinity DataEC50:  85nMAssay Description:Agonist activity at alphaVbeta3 integrin receptor in human SK-MEL-24 cells assessed as increase in fibronectin-induced cell adhesion pre-incubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of New Mexico School of Medicine

Curated by ChEMBL
LigandPNGBDBM50505770(CHEMBL4446073)copy SMILEScopy InChI
Affinity DataEC50:  154nMAssay Description:Agonist activity at alphaVbeta3 integrin receptor in human Saos-2 cells assessed as increase in fibronectin-induced cell adhesion pre-incubated for 3...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of New Mexico School of Medicine

Curated by ChEMBL
LigandPNGBDBM50550225(CHEMBL4764510)copy SMILES
Affinity DataEC50:  187nMAssay Description:Agonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibron...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of New Mexico School of Medicine

Curated by ChEMBL
LigandPNGBDBM50505776(CHEMBL4454796)copy SMILEScopy InChI
Affinity DataEC50:  299nMAssay Description:Agonist activity at alphaVbeta3 integrin receptor in human Saos-2 cells assessed as increase in fibronectin-induced cell adhesion pre-incubated for 3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of New Mexico School of Medicine

Curated by ChEMBL
LigandPNGBDBM50505774(CHEMBL4469125)copy SMILEScopy InChI
Affinity DataEC50:  984nMAssay Description:Agonist activity at alphaVbeta3 integrin receptor in human Saos-2 cells assessed as increase in fibronectin-induced cell adhesion pre-incubated for 3...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of New Mexico School of Medicine

Curated by ChEMBL
LigandPNGBDBM50505775(CHEMBL4442651)copy SMILEScopy InChI
Affinity DataEC50:  2.88E+3nMAssay Description:Agonist activity at alphaVbeta3 integrin receptor in human SK-MEL-24 cells assessed as increase in fibronectin-induced cell adhesion pre-incubated fo...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of New Mexico School of Medicine

Curated by ChEMBL
LigandPNGBDBM50021395(CHEMBL3289606)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibron...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of New Mexico School of Medicine

Curated by ChEMBL
LigandPNGBDBM50550222(CHEMBL4777693)copy SMILES
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibron...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of New Mexico School of Medicine

Curated by ChEMBL
LigandPNGBDBM50550226(CHEMBL4782288)copy SMILES
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibron...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of New Mexico School of Medicine

Curated by ChEMBL
LigandPNGBDBM50550224(CHEMBL4797755)copy SMILES
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibron...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of New Mexico School of Medicine

Curated by ChEMBL
LigandPNGBDBM50550227(CHEMBL4755971)copy SMILES
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibron...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of New Mexico School of Medicine

Curated by ChEMBL
LigandPNGBDBM50505772(CHEMBL4589062)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibron...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of New Mexico School of Medicine

Curated by ChEMBL
LigandPNGBDBM50505782(CHEMBL4586928)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alphaVbeta3 in human SK-MEL-24 cells assessed as increase in cell adhesion to fibronectin pre-incubated for 30 mins before fibron...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-V/beta-3(Homo sapiens (Human))
University of New Mexico School of Medicine

Curated by ChEMBL
LigandPNGBDBM50021395(CHEMBL3289606)copy SMILEScopy InChI
Affinity DataEC50:  1.04E+4nMAssay Description:Agonist activity at alphavbeta3 integrin in human SK-MEL-24 cells assessed as increase of fibronectin-mediated cell adhesion after 30 mins by fluores...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S75HWXPubMed