Compile Data Set for Download or QSAR
Found 21 of ec50 for UniProtKB: P05106
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50365354(CHEMBL1956150)copy SMILEScopy InChI
Affinity DataEC50:  7.80nMAssay Description:Inhibition of integrin alpha2bbeta3-mediated platelet aggregation in human TRAP-6-activated whole blood for 6 mins by impedence-based aggregometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90H4PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50004058((2S)-2-(butylsulfonylamino)-3-[4-(4-piperidin-4-yl...)copy SMILEScopy InChI
Affinity DataEC50:  13.6nMAssay Description:Inhibition of integrin alpha2bbeta3-mediated platelet aggregation in human TRAP-6-activated whole blood for 6 mins by impedence-based aggregometryMore data for this Ligand-Target Pair
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50365350(CHEMBL1956154)copy SMILEScopy InChI
Affinity DataEC50:  40.8nMAssay Description:Inhibition of integrin alpha2bbeta3-mediated platelet aggregation in human TRAP-6-activated whole blood for 6 mins by impedence-based aggregometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90H4PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50365352(CHEMBL1956152)copy SMILEScopy InChI
Affinity DataEC50:  276nMAssay Description:Inhibition of integrin alpha2bbeta3-mediated platelet aggregation in human TRAP-6-activated whole blood for 6 mins by impedence-based aggregometryMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MC90H4PubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50505779(CHEMBL4461771)copy SMILEScopy InChI
Affinity DataEC50:  311nMAssay Description:Agonist activity at alpha2bbeta3 in human HEL cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen a...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50550224(CHEMBL4797755)copy SMILES
Affinity DataEC50:  1.56E+3nMAssay Description:Agonist activity at alpha2bbeta3 in human HEL cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50222360(Ac-Asp-Arg-Leu-Asp-Ser-OH | CHEMBL238484)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha2bbeta3 in human HEL cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen a...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50550223(CHEMBL4794300)copy SMILES
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha2bbeta3 in human HEL cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50550222(CHEMBL4777693)copy SMILES
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha2bbeta3 in human HEL cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50021395(CHEMBL3289606)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha2bbeta3 in human HEL cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen a...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50021394(CHEMBL3289605)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha2bbeta3 in human HEL cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen a...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50021393(CHEMBL3289604)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha2bbeta3 in human HEL cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen a...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50550226(CHEMBL4782288)copy SMILES
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha2bbeta3 in human HEL cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50550227(CHEMBL4755971)copy SMILES
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha2bbeta3 in human HEL cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50505781(CHEMBL4461668)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha2bbeta3 in human HEL cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50550228(CHEMBL4743438)copy SMILES
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha2bbeta3 in human HEL cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50505772(CHEMBL4589062)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha2bbeta3 in human HEL cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen a...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50505782(CHEMBL4586928)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha2bbeta3 in human HEL cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50550225(CHEMBL4764510)copy SMILES
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha2bbeta3 in human HEL cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50439683(CHEMBL2418221)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha2bbeta3 in human HEL cells assessed as increase in cell adhesion to fibrinogen pre-incubated for 30 mins before fibrinogen a...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-IIb/beta-3(Homo sapiens (Human))
Technische Universit£t M£nchen

Curated by ChEMBL
LigandPNGBDBM50139204(3-[4-(3-Guanidino-benzoylamino)-phenylsulfanyl]-3-...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:Cell adhesion via integrin alphaIIb-beta3 expressed in CHO cells to fibrinogenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0N4QPubMed