Compile Data Set for Download or QSAR
Found 16 of ec50 for UniProtKB: P05556
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50535742(CHEMBL4592659)copy SMILEScopy InChI
Affinity DataEC50:  5.40nMAssay Description:Antagonist activity at integrin alpha4beta1 expressed in human Jurkat cells assessed as reduction in cell adhesion to human VCAM-1 incubated for 40 t...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70KB6PubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50505775(CHEMBL4442651)copy SMILEScopy InChI
Affinity DataEC50:  10nMAssay Description:Agonist activity at alpha4beta1 integrin receptor in human Jurkat E6.1 cells assessed as increase in VCAM1-induced cell adhesion pre-incubated for 30...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50505772(CHEMBL4589062)copy SMILEScopy InChI
Affinity DataEC50:  13nMAssay Description:Agonist activity at alpha4beta1 integrin receptor in human Jurkat E6.1 cells assessed as increase in VCAM1-induced cell adhesion pre-incubated for 30...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50505772(CHEMBL4589062)copy SMILEScopy InChI
Affinity DataEC50:  13nMAssay Description:Agonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as increase in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50505770(CHEMBL4446073)copy SMILEScopy InChI
Affinity DataEC50:  255nMAssay Description:Agonist activity at alpha4beta1 integrin receptor in human Jurkat E6.1 cells assessed as increase in VCAM1-induced cell adhesion pre-incubated for 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50505778(CHEMBL4447762)copy SMILEScopy InChI
Affinity DataEC50:  976nMAssay Description:Agonist activity at alpha4beta1 integrin receptor in human Jurkat E6.1 cells assessed as increase in VCAM1-induced cell adhesion pre-incubated for 30...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB567MPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50021395(CHEMBL3289606)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as increase in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50505782(CHEMBL4586928)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as increase in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50550224(CHEMBL4797755)copy SMILES
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as increase in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50505779(CHEMBL4461771)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as increase in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50550227(CHEMBL4755971)copy SMILES
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as increase in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50550228(CHEMBL4743438)copy SMILES
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as increase in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50021394(CHEMBL3289605)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as increase in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50021393(CHEMBL3289604)copy SMILEScopy InChI
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as increase in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and ...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50550226(CHEMBL4782288)copy SMILES
Affinity DataEC50: >5.00E+3nMAssay Description:Agonist activity at alpha4beta1 in human Jurkat E6.1 cells assessed as increase in cell adhesion to VCAM1 pre-incubated for 30 mins before VCAM1 and ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2154MPKPubMed
TargetIntegrin alpha-4/beta-1(Homo sapiens (Human))
Gilead Sciences

Curated by ChEMBL
LigandPNGBDBM50139204(3-[4-(3-Guanidino-benzoylamino)-phenylsulfanyl]-3-...)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+5nMAssay Description:CEMD9 cell adhesion via integrin alpha4-beta1 to VCAM1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RV0N4QPubMed