Compile Data Set for Download or QSAR
Found 23 of ec50 for UniProtKB: P56696
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50465773(CHEMBL4277250)copy SMILEScopy InChI
Affinity DataEC50:  20nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3H0DPubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50526876(CHEMBL4457044)copy SMILEScopy InChI
Affinity DataEC50:  80nMAssay Description:Activation of human Kv7.4 expressed in CHO cells assessed as increase in channel current amplitude by whole cell patch clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5KG2PubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50592357(CHEMBL5185685)copy SMILES
Affinity DataEC50:  87nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571H05PubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50526877(CHEMBL4545892)copy SMILEScopy InChI
Affinity DataEC50:  100nMAssay Description:Activation of human Kv7.4 expressed in CHO cells assessed as increase in channel current amplitude by whole cell patch clamp electrophysiology assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KW5KG2PubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50465774(CHEMBL4287894)copy SMILEScopy InChI
Affinity DataEC50:  100nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3H0DPubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50465777(CHEMBL4288707)copy SMILEScopy InChI
Affinity DataEC50:  160nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3H0DPubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50592355(CHEMBL5200636)copy SMILES
Affinity DataEC50:  320nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571H05PubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50121051(CHEMBL3621437)copy SMILEScopy InChI
Affinity DataEC50:  625nMAssay Description:Activation of human Kv7.4 expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28054FGPubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50592360(CHEMBL4549229)copy SMILES
Affinity DataEC50:  660nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571H05PubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50521289(CHEMBL4588394)copy SMILEScopy InChI
Affinity DataEC50:  780nMAssay Description:Agonist activity at human KCNQ4 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP27TTPubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50521287(CHEMBL4448132)copy SMILEScopy InChI
Affinity DataEC50:  890nMAssay Description:Activation of human homomeric KCNQ4 expressed in CHOK1 cells at -10 mV by whole cell patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP27TTPubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50592356(CHEMBL4458793)copy SMILES
Affinity DataEC50:  910nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2571H05PubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50521288(CHEMBL4438770)copy SMILEScopy InChI
Affinity DataEC50:  1.42E+3nMAssay Description:Agonist activity at human KCNQ4 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP27TTPubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50465775(CHEMBL1703636)copy SMILEScopy InChI
Affinity DataEC50:  1.60E+3nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50143558(CHEMBL41355 | EZOGABINE | N-(2-amino-4-(4-fluorobe...)copy SMILEScopy InChI
Affinity DataEC50:  1.98E+3nMAssay Description:Activation of human Kv7.4 expressed in CHO cells assessed as increase in channel current amplitude by whole cell patch clamp electrophysiology assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50521286(CHEMBL4450214)copy SMILEScopy InChI
Affinity DataEC50:  2.03E+3nMAssay Description:Agonist activity at human KCNQ4 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NP27TTPubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50426567(BMS-204352 | FLINDOKALNER | MaxiPost)copy SMILEScopy InChI
Affinity DataEC50:  2.40E+3nMAssay Description:Positive modulatory activity at voltage-gated K channel 7.4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B61GZPubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50465778(CHEMBL4287478)copy SMILEScopy InChI
Affinity DataEC50:  4.00E+3nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3H0DPubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50143558(CHEMBL41355 | EZOGABINE | N-(2-amino-4-(4-fluorobe...)copy SMILEScopy InChI
Affinity DataEC50:  5.90E+3nMAssay Description:Agonist activity at human KCNQ4 expressed in CHOK1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50594442(CHEMBL5178988)copy SMILES
Affinity DataEC50:  6.40E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GQ72RJPubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50465779(CHEMBL4278049)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3H0DPubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50420049(CHEMBL402146)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of human Kv7.4 by patch clamp methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28W3H0DPubMed
TargetPotassium voltage-gated channel subfamily KQT member 4(Homo sapiens (Human))
GlaxoSmithKline

Curated by ChEMBL
LigandPNGBDBM50390916(CHEMBL2070953)copy SMILEScopy InChI
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of KCNQ4 channel expressed in CHO cells assessed as depolarization-induced thallium influx after 3 mins by patch clamp assay relative to c...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q25T3MKNPubMed