Compile Data Set for Download or QSAR
Found 60 of ec50 for UniProtKB: P48775
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511728(CHEMBL4577396)copy SMILEScopy InChI
Affinity DataEC50:  32nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511724(CHEMBL4468203)copy SMILEScopy InChI
Affinity DataEC50:  33nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511731(CHEMBL4544695)copy SMILEScopy InChI
Affinity DataEC50:  35nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511709(CHEMBL4555603)copy SMILEScopy InChI
Affinity DataEC50:  36nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511714(CHEMBL4520696)copy SMILEScopy InChI
Affinity DataEC50:  39nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511717(CHEMBL4437257)copy SMILEScopy InChI
Affinity DataEC50:  48nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511723(CHEMBL4445816)copy SMILEScopy InChI
Affinity DataEC50:  50nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511727(CHEMBL4447185)copy SMILEScopy InChI
Affinity DataEC50:  50nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511730(CHEMBL4590789)copy SMILEScopy InChI
Affinity DataEC50:  54nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511710(CHEMBL4541824)copy SMILEScopy InChI
Affinity DataEC50:  60nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511725(CHEMBL4593111)copy SMILEScopy InChI
Affinity DataEC50:  62nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511716(CHEMBL4539108)copy SMILEScopy InChI
Affinity DataEC50:  65nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511722(CHEMBL4531114)copy SMILEScopy InChI
Affinity DataEC50:  70nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511713(CHEMBL4467673)copy SMILEScopy InChI
Affinity DataEC50:  71nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511719(CHEMBL4548068)copy SMILEScopy InChI
Affinity DataEC50:  72nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50321330(CHEMBL4166624)copy SMILEScopy InChI
Affinity DataEC50:  77nMAssay Description:Inhibition of TDO2 in human SW48 cells assessed as decrease in conversion of tryptophan to N-formylkynurenine after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0481GPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50321330(CHEMBL4166624)copy SMILEScopy InChI
Affinity DataEC50:  77nMAssay Description:Inhibition of TDO (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73J3GPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50321318(CHEMBL4166415)copy SMILEScopy InChI
Affinity DataEC50:  85nMAssay Description:Inhibition of TDO2 in human SW48 cells assessed as decrease in conversion of tryptophan to N-formylkynurenine after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0481GPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511718(CHEMBL4542307)copy SMILEScopy InChI
Affinity DataEC50:  87nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50321325(CHEMBL4173485)copy SMILEScopy InChI
Affinity DataEC50:  99nMAssay Description:Inhibition of TDO2 in human SW48 cells assessed as decrease in conversion of tryptophan to N-formylkynurenine after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0481GPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511711(CHEMBL4439294)copy SMILEScopy InChI
Affinity DataEC50:  130nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511729(CHEMBL4589215)copy SMILEScopy InChI
Affinity DataEC50:  130nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511715(CHEMBL4540245)copy SMILEScopy InChI
Affinity DataEC50:  210nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50321942(CHEMBL4170773)copy SMILEScopy InChI
Affinity DataEC50:  210nMAssay Description:Inhibition of TDO2 in human SW48 cells assessed as decrease in conversion of tryptophan to N-formylkynurenine after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0481GPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50321319(CHEMBL4168975)copy SMILEScopy InChI
Affinity DataEC50:  230nMAssay Description:Inhibition of TDO2 in human SW48 cells assessed as decrease in conversion of tryptophan to N-formylkynurenine after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0481GPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50321386(CHEMBL4170344)copy SMILEScopy InChI
Affinity DataEC50:  250nMAssay Description:Inhibition of TDO2 in human SW48 cells assessed as decrease in conversion of tryptophan to N-formylkynurenine after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0481GPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50138828(CHEMBL3752060 | US10233190, Example 1417)copy SMILEScopy InChI
Affinity DataEC50:  250nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50321329(CHEMBL4177244)copy SMILEScopy InChI
Affinity DataEC50:  340nMAssay Description:Inhibition of TDO2 in human SW48 cells assessed as decrease in conversion of tryptophan to N-formylkynurenine after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0481GPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50321331(CHEMBL4166941)copy SMILEScopy InChI
Affinity DataEC50:  360nMAssay Description:Inhibition of TDO2 in human SW48 cells assessed as decrease in conversion of tryptophan to N-formylkynurenine after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0481GPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511726(CHEMBL4440730)copy SMILEScopy InChI
Affinity DataEC50:  380nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50321436(CHEMBL4162962)copy SMILEScopy InChI
Affinity DataEC50:  670nMAssay Description:Inhibition of TDO2 in human SW48 cells assessed as decrease in conversion of tryptophan to N-formylkynurenine after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0481GPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50321332(CHEMBL4165554)copy SMILEScopy InChI
Affinity DataEC50:  810nMAssay Description:Inhibition of TDO2 in human SW48 cells assessed as decrease in conversion of tryptophan to N-formylkynurenine after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0481GPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50335565(CHEMBL4176841)copy SMILEScopy InChI
Affinity DataEC50:  810nMAssay Description:Inhibition of TDO2 in human SW48 cells assessed as decrease in conversion of tryptophan to N-formylkynurenine after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0481GPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50321321(CHEMBL4165043)copy SMILEScopy InChI
Affinity DataEC50:  820nMAssay Description:Inhibition of TDO2 in human SW48 cells assessed as decrease in conversion of tryptophan to N-formylkynurenine after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0481GPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50321335(CHEMBL4160126)copy SMILEScopy InChI
Affinity DataEC50:  950nMAssay Description:Inhibition of TDO2 in human SW48 cells assessed as decrease in conversion of tryptophan to N-formylkynurenine after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0481GPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50606613(CHEMBL5219865)copy SMILES
Affinity DataEC50:  1.07E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474G0KPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50321323(CHEMBL4177147)copy SMILEScopy InChI
Affinity DataEC50:  1.40E+3nMAssay Description:Inhibition of TDO2 in human SW48 cells assessed as decrease in conversion of tryptophan to N-formylkynurenine after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0481GPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511720(CHEMBL4558670)copy SMILEScopy InChI
Affinity DataEC50:  1.40E+3nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50335520(CHEMBL4162432)copy SMILEScopy InChI
Affinity DataEC50:  1.50E+3nMAssay Description:Inhibition of TDO2 in human SW48 cells assessed as decrease in conversion of tryptophan to N-formylkynurenine after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0481GPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50335521(CHEMBL4159044)copy SMILEScopy InChI
Affinity DataEC50:  1.50E+3nMAssay Description:Inhibition of TDO2 in human SW48 cells assessed as decrease in conversion of tryptophan to N-formylkynurenine after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0481GPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM370555((1R,4r)-4-((R)-2-((S)-6-fluoro-5H-imidazo[5,1- a]i...)copy SMILEScopy InChI
Affinity DataEC50:  1.51E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474G0KPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM370555((1R,4r)-4-((R)-2-((S)-6-fluoro-5H-imidazo[5,1- a]i...)copy SMILEScopy InChI
Affinity DataEC50:  2.00E+3nMAssay Description:Inhibition of TDO (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511721(CHEMBL4473543)copy SMILEScopy InChI
Affinity DataEC50:  3.00E+3nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM370555((1R,4r)-4-((R)-2-((S)-6-fluoro-5H-imidazo[5,1- a]i...)copy SMILEScopy InChI
Affinity DataEC50:  3.00E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474G0KPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50606613(CHEMBL5219865)copy SMILES
Affinity DataEC50:  3.03E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474G0KPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50511712(CHEMBL4529817)copy SMILEScopy InChI
Affinity DataEC50:  7.40E+3nMAssay Description:Inhibition of TDO in human SW48 cells after 24 hrs by NFK green reagent based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RR22JSPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50440736(CHEMBL2431088)copy SMILEScopy InChI
Affinity DataEC50:  9.70E+3nMAssay Description:Inhibition of TDO2 in human SW48 cells assessed as decrease in conversion of tryptophan to N-formylkynurenine after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0481GPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50321328(CHEMBL4163495)copy SMILEScopy InChI
Affinity DataEC50:  1.80E+4nMAssay Description:Inhibition of TDO2 in human SW48 cells assessed as decrease in conversion of tryptophan to N-formylkynurenine after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0481GPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50335922(CHEMBL4163311)copy SMILEScopy InChI
Affinity DataEC50: >2.50E+4nMAssay Description:Inhibition of TDO2 in human SW48 cells assessed as decrease in conversion of tryptophan to N-formylkynurenine after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0481GPubMed
TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50321320(CHEMBL4168362)copy SMILEScopy InChI
Affinity DataEC50: >2.50E+4nMAssay Description:Inhibition of TDO2 in human SW48 cells assessed as decrease in conversion of tryptophan to N-formylkynurenine after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M0481GPubMed
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