Compile Data Set for Download or QSAR
Found 4 of ec50 for UniProtKB: P25025
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Syntrix Biosystems, Inc.

US Patent
LigandPNGBDBM150812(US8981106, 2 (SX-576) | USRE47267, Compound 2)copy SMILEScopy InChI
Affinity DataEC50:  1.25E+3nMAssay Description:The assay is a Ca2+ mobilization assay that measures changes in intracellular Ca2+ with a FlexStation II scanning fluorometer using a FLIPR-3 Calcium...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GF0WSHUS Patent
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Syntrix Biosystems, Inc.

US Patent
LigandPNGBDBM150824(US8981106, 14 (SX-585) | USRE47267, Compound 14)copy SMILEScopy InChI
Affinity DataEC50:  1.81E+3nMAssay Description:The assay is a Ca2+ mobilization assay that measures changes in intracellular Ca2+ with a FlexStation II scanning fluorometer using a FLIPR-3 Calcium...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GF0WSHUS Patent
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Syntrix Biosystems, Inc.

US Patent
LigandPNGBDBM150822(US8981106, 13 (SX-578) | USRE47267, Compound 13)copy SMILEScopy InChI
Affinity DataEC50:  2.40E+3nMAssay Description:The assay is a Ca2+ mobilization assay that measures changes in intracellular Ca2+ with a FlexStation II scanning fluorometer using a FLIPR-3 Calcium...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GF0WSHUS Patent
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Syntrix Biosystems, Inc.

US Patent
LigandPNGBDBM50255479(CHEMBL4067429)copy SMILEScopy InChI
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at TEV protease cleavage site linked GAL4-VP16-fused recombinant human CXCR2 expressed in cells assessed as induction of beta-arrest...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2959M1FPubMed